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Japan’s problem of vacant homes has drawn global media attention, but the situation may not be as dire as once predicted. While a 2015 report estimated a vacancy rate of 20.1 per cent by 2023, the actual figure was 13.8 per cent, thanks in part to policy reforms, awareness campaigns and grassroots efforts. Yet challenges remain amid an ageing population. Japan’s evolving approach offers valuable l
This study presents an example of when the government introduced a regulation that did not coincide research, professional ethics, responsibility or commitments, and led to a conflict between professionals and rulers.In the Swedish statutes regulating opioid maintenance treatment (OMT), a unique definition of the term opiate-dependency, the opiate rule, was introduced in 2010—restricting the targe
Pulmonary fibrosis remains a devastating and often fatal condition due to the lack of effective treatments that halt disease progression. Rodent models of pulmonary fibrosis are crucial to identify candidate targets and novel therapeutic agents. However, the attrition rate of novel drug candidates in clinical trials remains high. This review suggests complementing traditional methods used to evalu
Particle induced oxidative stress is a probable pathway for many of the detrimental health-effects caused by particulate matter (PM). Recent studies on the exposure to oxidative potential (OP) in ambient fine and coarse PM suggest that anthropogenic particle pollutants, especially vehicular wear, anthropogenic primary and secondary organic aerosols (SOA) are more toxic on mass basis and more relev
Non-exhaust emissions from the wear of brakes, tyres, and roads have become an increasing concern in recent years, already surpassing exhaust emissions by mass in many countries. However, there is a lack of studies in the scientific literature on test methods that include both real tyre and road materials. This is crucial for accurately replicating the tribological mechanisms and resulting emissio
As found in the health studies literature, the levels of climate association between epidemiological diseases have been found to vary across regions. Therefore, it seems reasonable to allow for the possibility that relationships might vary spatially within regions. We implemented the geographically weighted random forest (GWRF) machine learning method to analyze ecological disease patterns caused
This detailed volume presents a diverse set of methodological approaches designed to improve our understanding of bacterial infections from a wide range of bacterial species. Beginning with biofilms and subcellular compartments, the book explores transcriptional analysis, methods for studying plasmid dynamics, and tools for phylogenetic analysis of bacterial genomes, as well as bacterial effector
Integration of fiber modification step with a modern pulp mill is a resource efficient way to produce functional fibers. Motivated by the need to integrate polymer adsorption with the current pulping system, anion-specific effects in carboxymethylcellulose (CMC) adsorption have been studied. The QCM-D adsorption experiments revealed that CMC adsorption to the cellulose model surface is prone to an
Older women make a significant contribution to the labour market yet still experiencenegative workplace impacts. We undertook a rapid review of literature to assess theexperiences of older female workers in the European labour market with the aim toidentify current research gaps. We discuss how current data and future research couldbe utilized to improve the working lives of older women in Europe.
AIMS: To describe the level of physical activity 6 months after an out-of-hospital cardiac arrest (OHCA) and to explore potential risk factors of a low level of physical activity.METHODS: Post-hoc analyses of the international multicentre Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac arrest (TTM2) trial. At 6 months, survivors at 61 sites in Europe, Australia and
The complex dynamics of protein expression in plasma during hyperacute HIV-1 infection and its relation to acute retroviral syndrome, viral control, and disease progression are largely unknown. Here, we quantify 1293 blood plasma proteins from 157 longitudinally linked plasma samples collected before, during, and after hyperacute HIV-1 infection of 54 participants from four sub-Saharan African cou
BACKGROUND: Melanoma is a highly heterogeneous disease, and a deeper molecular classification is essential for improving patient stratification and treatment approaches. Here, we describe the histopathology-driven proteogenomic landscape of 142 treatment-naïve metastatic melanoma samples to uncover molecular subtypes and clinically relevant biomarkers.METHODS: We performed an integrative proteogen
Background: Previous population-based studies investigating the relationship between physical activity and the gut microbiota have relied on self-reported activity, prone to reporting bias. Here, we investigated the associations of accelerometer-based sedentary (SED), moderate-intensity (MPA), and vigorous-intensity (VPA) physical activity with the gut microbiota using cross-sectional data from th
Objectives Better understanding of societal factors associated with COVID-19 vaccination can have important implications for public health policy to increase uptake.Methods This study investigated sociodemographic determinants of COVID-19 vaccine uptake with ≥2 doses vs 0 doses, and ≥3 doses vs 2 doses, among adults (≥18 years) in a general population from Sweden followed from 27 December 2020 (n=
Significant amount of studies have found evidence on the effects of land ownership on child labor suggesting that land-rich households tend to employ their children more than land-poor households, this phenomenon was labeled as “the wealth paradox”. In this study we include enterprise ownership in the empirical analysis to investigate the effect of ownership and the size of such assets on child la
Since the 1970s, the practice of conscripting, enlisting or recruiting children into armed groups or forces has become increasingly common, and many children are used for various tasks in conflicts around the globe. Children are easily persuaded or forced into such armed groups or forces, and they suffer great harm from exposure to violence. Girls are generally recruited in the same manner as boys
Responsibility and freedom : a study in managing copyright and trademark Avsikten med uppsatsen har varit att undersöka sambandet mellan författare och varumärke. Utifrån Moomin Characters Oy och Saltkråkan AB, vilka förvaltar Tove Janssons respektive Astrid Lindgrens rättigheter, har arbetet identifierat verksamheternas varumärken och mål. Varumärken som skiljer sig mellan verksamhet och förfat
