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BACKGROUND: The objective of the Swedish cleft lip and palate (CLP) registry is to promote quality control, research and improvement of treatment, by comparison of the long-term results of surgery, orthodontics and speech from all six Swedish CLP centres. The purpose of the study was to investigate the coverage and reporting degree of the Swedish CLP registry, and to describe the design of the reg
Groundwater (GW) resources provide a large share of the world's water demand for various sections such as agriculture, industry, and drinking water. Particularly in the arid and semi-arid regions, with surface water scarcity and high evaporation, GW is a valuable commodity. Yet, GW data are often incomplete or nonexistent. Therefore, it is a challenge to achieve a GW potential assessment. In this
Recent data resulting from studies of two-nucleon transfer reaction on 11Li, analyzed through a unified nuclear-structure-direct-reaction theory have provided strong direct as well as indirect confirmation, through the population of the first excited state of 9Li and of the observation of a strongly quenched ground state transition, of the prediction that phonon-mediated pairing interaction is the
BACKGROUND: The evaluation of lymph nodes (LN) by fine-needle aspiration cytology (FNAC) is routinely used in many institutions but it is not uniformly accepted mainly because of the lack of guidelines and a cytopathological diagnostic classification. A committee of cytopathologists has developed a system of performance, classification, and reporting for LN-FNAC. METHODS: The committee members pre
Difficulty in obtaining bone tissue is an obstacle to studying epigenetics to understand gene–environment interactions, and their role in disease pathogenesis. Blood is an obvious alternative and in this proof of principle study, our aim was to systematically investigate whether blood is a viable surrogate for bone. We measured epigenome-wide DNA methylation at 850 K CpG sites in matched trabecula
Background: While discontinuation of COPD maintenance medication is a known problem, the proportion of patients with discontinuation and its geographical and sociodemographic distribution are so far unknown in Sweden. Therefore, we analyse this question by applying an innovative approach called multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA). Patients and Metho
The proton linac of the European Spallation Source, under construction in Lund, Sweden, had beam commissioning of its ion source (IS) and the following low energy beam transport (LEBT) at their final locations from September 2018 to July 2019. This was first of several beam commissioning stages for the linac of ESS, towards the start of the user program in 2023. This paper presents highlights of c
Smart cyber-physical systems (S-CPSs) are complex engineered systems empowered by cyber-physical computing and equipped with the capability of reasoning, learning, adapting, and evolving. As an outcome of data-driven dynamic computing, reasoning capabilities, and the run-time obtained own knowledge, nonlinear and emergent behavior of S-CPSs whilst in operation is an open issue, not experienced in
Introduction: Post-traumatic stress disorder (PTSD) and substance use disorder frequently co-occur and tend to have their onset during adolescence. Although research has highlighted the importance of treating these disorders in an integrated fashion, there is a dearth of empirically validated integrated treatment options for adolescents with this comorbidity. This paper describes the study protoco
Objective: The authors aimed to clarify the sources of parent-child transmission for suicide attempt and death by suicide. Methods: Three sources of parent-child resemblance (genes plus rearing, genes only, and rearing only) were examined in parents and offspring from four family types from Swedish national samples: intact nuclear families, families with a not-lived-with biological father, familie
PURPOSE: To explore the frequency and outcomes of cataract surgery in eyes with previous vitrectomy. SETTING: Fifteen European countries. DESIGN: Retrospective cross-sectional register-based study. METHODS: The European Registry of Quality Outcomes of Cataract and Refractive Surgery (EUREQUO) contains data on baseline characteristics, surgery, and follow-up for cataract surgeries. Previous vitrect
Context. NGC 2264 is a young cluster whose accretion properties can be investigated in detail by taking advantage of the FLAMES data in the context of the Gaia-ESO Survey. In fact, the analysis of the Hα emission line profile can provide us with information about the accretion and ejection activity of young stars. However, a strong nebular emission that contributes to the Hα emission can alter the
The pharmaceutical and healthcare sector is a prime target for cybercriminals around the world. These cyber-attacks represent significant challenges in the context of data protection and data security. The General Data Protection Regulation (GDPR) imposes strict rules regarding the processing and analysis of personal data. In conventional approaches, data analysts request data from various sources
The comparative study of planetary systems is a unique source of new scientific insight: following the six “key science questions” of the “Planetary Exploration, Horizon 2061” long-term foresight exercise, it can reveal to us the diversity of their objects (Question 1) and of their architectures (Question 2), help us better understand their origins (Question 3) and how they work (Question 4), find
As climate models can be used to reproduce historical climates, the outcomes can be used to put climate extremes in to a proper historical perspective. This also allows investigation of nonlinear properties of hydrologic processes (e.g. precipitation, runoff) to better understand regional hydrologic dynamics. To this end, the present study uses results from a so-called 'paleosimulation' (i.e. simu
Children with bone marrow failure syndromes and severe aplastic anemia (SAA) are treated with allogeneic blood or marrow transplantation (BMT). However, there is a paucity of studies examining late mortality risk after allogeneic BMT performed in childhood for bone marrow failure syndromes and SAA and evaluating how this risk differs between these diseases. We investigated cause-specific late mort
This work investigates the stability of emulsions prepared by using octenyl succinic anhydride (OSA)-modified waxy maize starch in the form of granules, dissolved starch, and non-solvent precipitated starch as Pickering emulsion stabilisers. The aim of this study was to investigate the effects of different forms of starches on the stability of emulsion using light microscopy, light scattering, and
