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Background: Liver disease and dementia are both highly prevalent and share common pathological mechanisms. We aimed to investigate the associations between metabolic dysfunction-associated fatty liver disease (MAFLD), metabolic dysfunction-associated steatotic liver disease (MASLD) and the risk of all-cause and cause-specific dementia. Methods: We conducted a prospective study with 403,506 partici
BACKGROUND: Accumulating studies reported that several phosphodiesterases (PDEs) inhibitors might have cardiovascular benefits.OBJECTIVES: This study aimed to explore the relationship between genetically-predicted PDEs and ischemia heart disease via drug target Mendelian randomization (MR) approach, and then examine the effect of inhibitors of identified target on the outcomes by using real-world
Background: Little is known about whether the protective effect of marriage on alcohol use disorder (AUD) varies by cultural background. Aims: Using Swedish national data, we examined whether marriage is associated with a stronger reduction in AUD risk among Swedes of a Swedish background (i.e. those with two Swedish-born parents) compared to Swedes with a foreign background (i.e. one or two forei
Background: The Finnish Shaft of the Humerus (FISH) trial compared open reduction and internal plate fixation (ORIF) with functional bracing in adult patients with displaced, closed humeral shaft fractures. Here, we compare the results of the patients in the randomized clinical trial (RCT [the randomized cohort]) with those of the cohort of patients who were also eligible but declined randomizatio
Atrial fibrillation (AF) is a complex condition caused by various underlying pathophysiological disorders and is the most common heart arrhythmia worldwide, affecting 2 % of the European population. This prevalence increases with age, imposing significant financial, economic, and human burdens. In Europe, stroke is the second leading cause of death and the primary cause of disability, with numbers
Kultur och ekologi i Amazonas: GIS-bearbetning av historiska data om indianfolkens utbredning Love Eriksen D-uppsats i Humanekologi: Miljö, kultur och utveckling, IV (61-80 poäng) HEK254 Humanekologiska avdelningen Etnologiska institutionen Lunds universitet Handledare: Alf Hornborg Biträdande handledare: Andreas Persson Abstract This study deals with some contested issues regarding prehistoric cu
https://www.keg.lu.se/en/sites/keg.lu.se.en/files/_alf2.pdf - 2026-07-22
Mall för kursplaner på grundnivå och avancerad nivå inom naturvetenskapliga fakulteten GEON04 Kursplan för Kvartärgeologi: Global och regional maringeologi 15 högskolepoäng, Quaternary Geology: Global and Regional Marine Geology 15 higher education credits 1. Grundläggande uppgifter Fastställd av naturvetenskapliga fakultetens utbildningsnämnd 2012-01-24. Planen träder i kraft 2012-01-16. Kursen ä
https://www.geologi.lu.se/sites/geologi.lu.se/files/geon04-kursplan.pdf - 2026-07-22
ETHANOL FUEL PRODUCTION AND USE IN KENYA FOR SUSTAINABLE DEVELOPMENT LUND UNIVERSITY International Masters Programme in Environmental Science ETHANOL FUEL PRODUCTION AND USE IN KENYA FOR SUSTAINABLE DEVELOPMENT A Thesis Submitted in Partial Fulfilment for the Award of a Master of Science Degree in Environmental Science at Lund University, Sweden Author: Supervisor: Leah Wanambwa Barry Ness LUMES L
https://www.lumes.lu.se/sites/lumes.lu.se/files/leah_wanambwa.pdf - 2026-07-22
Microsoft Word - DRAFT 3 Master’s thesis Landscape planning from a child’s perspective A case study in the Vombsänkan in southernmost Sweden Lund, 25 May 2009 Lund University Master’s Programme in Environmental Studies and Sustainability Science “LUMES” Submitted by: Mirjam van der Hoek mirjamvanderhoek@hotmail.com Supervised by: Göran Ewald goran.ewald@lucsus.lu.se 2 Abstract Landscapes are mostl
https://www.lumes.lu.se/sites/lumes.lu.se/files/vanderhoek_mirjam_0.pdf - 2026-07-22
The importance of land-atmosphere biophysical interactions for regional climate and terrestrial ecosystem change Improved understanding to inform Swedish national climate action CEC SYNTHESIS NO 05 | 2020 | LUND UNIVERSITY Centre for Environmental and Climate Research Lund University CEC Synthesis No 05 ISBN 978-91-984349-3-4 (print) ISBN 978-91-984349-4-1 (pdf) The synthesis aims to lay the found
Objectives The aim of this study was to confirm the influence of TNFSF4 polymorphisms on systemic sclerosis (SSc) susceptibility and phenotypic features. Methods A total of 8 European populations of Caucasian ancestry were included, comprising 3014 patients with SSc and 3125 healthy controls. Four genetic variants of TNFSF4 gene promoter (rs1234314, rs844644, rs844648 and rs12039904) were selected
BACKGROUND: There is an increasing interest in cognitive and functional outcomes in the respective stages of Alzheimer's disease (AD) and in novel therapies particularly for the milder phases of AD. Our aim was to describe and compare various aspects of disease progression in patients with mild versus moderate AD in routine clinical practice of cholinesterase inhibitor (ChEI) therapy. METHODS: Thi
Background: Selective dorsal rhizotomy (SDR) is a well accepted neurosurgical procedure performed for the relief of spasticity interfering with motor function in children with spastic cerebral palsy (CP). The goal is to improve function, but long-term outcome studies are rare. The aims of this study were to evaluate long-term functional outcomes, safety and side effects during five postoperative y
Background: Subjects with non-O ABO blood group alleles have increased risk of pancreatic cancer. Glycosyltransferase activity is greater for the A(1) versus A(2) variant, whereas O01 and O02 variants are nonfunctioning. We hypothesized: 1) A(1) allele would confer greater risk than A(2) allele, 2) protective effect of the O allele would be equivalent for O01 and O02 variants, 3) secretor phenotyp
Background: In previous meta-analyses, tea consumption has been associated with lower incidence of type 2 diabetes. It is unclear, however, if tea is associated inversely over the entire range of intake. Therefore, we investigated the association between tea consumption and incidence of type 2 diabetes in a European population. Methodology/Principal Findings: The EPIC-InterAct case-cohort study wa
Objectives: To describe the contribution of highly processed foods to total diet, nutrient intakes and patterns among 27 redefined centres in the 10 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC). Methods: Single 24-hour dietary recalls were collected from 36 034 individuals (aged 35-74 years) using a standardized computerized interview programme
Objectives To study clinical predictors for radiographic progression after 1 year in an early rheumatoid arthritis (RA) trial. Methods In the SWEFOT trial population, disease modifying antirheumatic drug (DMARD) naive RA patients started methotrexate; 3-month responders (DAS28 <3.2) continued (n=147), while non-responders were randomised to addition of sulfasalazine +hydroxychloroquine (n=130) or
OBJECTIVE Patients with latent autoimmune diabetes in adults (LADA) express autoantibodies against the 65-kDa isoform of GAD (GADA). Intervention with recombinant human GAD65 formulated with aluminium hydroxide (GAD-alum) given twice subcutaneously to LADA patients at intervals of 4 weeks was safe and did not compromise beta-cell function in a Phase II clinical trial. GADA affinity has been shown
Background: Frontotemporal dementia (FTD) is recognised as a clinically and morphologically heterogeneous group of interrelated neurodegenerative conditions. One of the subtypes within this disease spectrum is the behavioural variant FTD (bvFTD). This is known to be a varied disorder with a mixture of tau-positive and tau-negative underlying pathologies. The other subtypes include semantic dementi
