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Quantitative assessment of the relationship between land use/land cover (LULC), topographic elevation and land surface temperature (LST) in Ilorin, Nigeria

The urbanization of landscapes and the increase in impervious land cover materials is known to cause significant changes in the landscape's thermal properties, typically leading to urban heat island (UHI). Although previous studies have investigated the impacts of land cover land use (LULC) and other factors on the urban land surface temperature (LST), the results of such studies are mixed. For in

Depression was associated with younger age, female sex, obesity, smoking, and physical inactivity, in 1027 patients with newly diagnosed type 2 diabetes : a Swedish multicentre cross-sectional study

Background: Depression is a risk factor for type 2 diabetes (T2D) and cardiovascular disease (CVD). The aims were to explore the prevalence of depression, anxiety, antidepressant use, obesity, Hemoglobin A1c > 64 mmol/mol, life-style factors, pre-existing CVD, in patients with newly diagnosed T2D; to explore associations with depression; and to compare with Swedish general population data. Methods

Using imlifidase to elucidate the characteristics and importance of anti-GBM antibodies produced after start of treatment

BACKGROUND: Autoantibodies are common in glomerulonephritis, but the clinical benefit of rapid elimination is not determined, even in anti-glomerular basement membrane (GBM) disease. Even less is known about the importance of autoantibody characteristics, including epitope specificity and IgG subclass distribution. By utilizing samples from the GOOD-IDES-01 trial, where imlifidase, cleaving all Ig

Coronary Artery Lesion Lipid Content and Plaque Burden in Diabetic and Nondiabetic Patients : PROSPECT II

BACKGROUND: Patients with diabetes have increased rates of major adverse cardiac events (MACEs). We hypothesized that this is explained by diabetes-associated differences in coronary plaque morphology and lipid content. METHODS: In PROSPECT II (Providing Regional Observations to Study Predictors of Events in the Coronary Tree), 898 patients with acute myocardial infarction with or without ST-segme

An emergent means to assurgent ends : Societal resilience for safety and sustainability

Societal safety and sustainability are key challenges in our complex and dynamic world, causing growth in interest of applying the concept of resilience in broader societal contexts. This chapter presents a concept of societal resilience that builds on established theory of Resilience Engineering and operationalises the concept by presenting its purpose, required functions and a way to identify an

Structure and laminar flame speed of an ammonia/methane/air premixed flame under varying pressure and equivalence ratio

This paper presents a joint experimental and numerical study on premixed laminar ammonia/methane/air flames, aiming to characterize the flame structures and NO formation and determine the laminar flame speed under different pressure, equivalence ratio, and ammonia fraction in the fuel. The experiments were carried out in a lab-scale pressurized vessel with a Bunsen burner installed with a concentr

Getting the picture of home lighting: Adding participant photography to the interview

This paper draws attention to the potential benefits of using photographs in combination with interviews, that is to say photo elicitation. As defined by Harper (2002), photo elicitation is “based on the simple idea of inserting a photograph into a research interview” (p. 13). The photographs can be taken by the researcher or the participant to evoke comments. If participants are asked to produce

The course and end-points of Alzheimer’s disease according to sociodemographics, apolipoprotein E genotype and cognitive ability.

Background: The prognosis of Alzheimer’s disease (AD) might be influenced by many sociodemographic and clinical factors. Previous studies have investigated the main effects of critical predictors but few have analyzed potential interactions. We have studied the long-term cognitive outcome, nursing home placement (NHP) and mortality by interactions between factors in cholinesterase inhibitor (ChEI)

Clinical aspects of molecular profiles in metastatic malignant melanoma

Malignant melanoma is a heterogeneous, malignant neoplastic disease, most often originating in the skin. Melanoma is characterized by a high mutational load and has a vastly variable prognosis, depending on disease stage. Genetic aberrations in the mitogen-activating protein kinase (MAPK) pathway are important in melanoma, of which mutations in BRAF and NRAS are the most common. Additionally, recu

COL1A1 Sp1 polymorphism predicts perimenopausal and early postmenopausal spinal bone loss

Genetic factors play an important role in the pathogenesis of osteoporosis but the genes that determine susceptibility to poor bone health are defined incompletely. Previous work has shown that a polymorphism that affects an Spl binding site in the COLIA1 gene is associated with reduced bone mineral density (BMD) and an increased risk of osteoporotic fracture in several populations. Data from cros

Randomized Trial of Sacroiliac Joint Arthrodesis Compared with Conservative Management for Chronic Low Back Pain Attributed to the Sacroiliac Joint

BACKGROUND: Sacroiliac joint pain is increasingly recognized as a cause of low back pain. We compared the safety and effectiveness of minimally invasive sacroiliac joint arthrodesis using triangular titanium implants and conservative management in patients with chronic sacroiliac joint pain. METHODS: This study was a prospective, multicenter randomized controlled trial of adults with chronic sacro

Risk of complications in patients with conservatively managed ovarian tumours (IOTA5) : a 2-year interim analysis of a multicentre, prospective, cohort study

Background: Ovarian tumours are usually surgically removed because of the presumed risk of complications. Few large prospective studies on long-term follow-up of adnexal masses exist. We aimed to estimate the cumulative incidence of cyst complications and malignancy during the first 2 years of follow-up after adnexal masses have been classified as benign by use of ultrasonography. Methods: In the

Associations between quantitative [18F]flortaucipir tau PET and atrophy across the Alzheimer's disease spectrum

Background: Neuropathological studies have linked tau aggregates to neuronal loss. To describe the spatial distribution of neurofibrillary tangle pathology in post-mortem tissue, Braak staging has been used. The aim of this study was to examine in vivo associations between tau pathology, quantified with [18F]flortaucipir PET in regions corresponding to Braak stages, and atrophy across the Alzheime

The Importance and Challenges of Anticipation for Community Resilience

Resilience is a debated concept with numerous definitions. If focusing on describing a community under stress of a particular disruptive event, its more traditional etymological meaning of ability to spring back after deformation, or its more applied meaning of ability to cope with and recover from the event, are sufficient. However, if focusing on building and maintaining resilient communities ov

Interval and Consecutive Round Breast Cancer after Digital Breast Tomosynthesis and Synthetic 2D Mammography versus Standard 2D Digital Mammography in BreastScreen Norway

Background: Screening that includes digital breast tomosynthesis (DBT) with two-dimensional (2D) synthetic mammography (SM) or standard 2D digital mammography (DM) results in detection of more breast cancers than does screening with DM alone. A decrease in interval breast cancer rates is anticipated but is not reported. Purpose: To compare rates and characteristics of (a) interval breast cancer in

High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus

OBJECTIVES: To investigate associations between a high genetic disease risk and disease severity in patients with systemic lupus erythematosus (SLE).METHODS: Patients with SLE (n=1001, discovery cohort and n=5524, replication cohort) and healthy controls (n=2802 and n=9859) were genotyped using a 200K Immunochip single nucleotide polymorphism array. A genetic risk score (GRS) was assigned to each

On norovirus outbreaks and transmission in hospitals

Abstract Noroviruses are now the leading cause of gastroenteritis worldwide. Noroviruses are effectively transmitted due to a low infectious dose, viral shedding in high concentrations, environmental stability, and they induce only a limited immunity after infection. Especially, the norovirus variants of genotype II.4 (GII.4) have seemed greatly adapted for pandemic spread. The high infectivity of