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BACKGROUND: It is generally argued that variations in cerebral blood flow create concomitant changes in the cerebral blood volume (CBV). Because nitrous oxide (N(2)O) inhalation both increases cerebral blood flow and may increase intracranial pressure, it is reasonable to assume that N(2)O acts as a general vasodilatator in cerebral vessels both on the arterial and on the venous side. The aim of t

Purpose Our focus was on patients with pediatric acute lymphoblastic leukemia (ALL) who experienced relapse or died without becoming transplantation candidates. The purpose was to outline measures needed to improve the outcome. Patients and Methods We analyzed our population-based 20-year data on 3,385 Nordic children with ALL treated on Nordic Society for Pediatric Hematology and Oncology ALL pro

Background Calcipotriol and betamethasone dipropionate are both widely used, effective treatments for psoriasis. Vitamin D analogues and topical corticosteroids have different mechanisms of action in the treatment of psoriasis. A new vehicle has been developed in order to contain both calcipotriol (50 micro g g-1) and betamethasone dipropionate (0.5 mg g-1) in an ointment form. By using calcipotri

Despite declining incidence rates, gastric cancer (GC) is a major cause of death worldwide. Its aetiology may involve dietary antioxidant micronutrients such as carotenoids and tocopherols. The objective of this study was to determine the association of plasma levels of seven common carotenoids, their total plasma concentration, retinol and alpha- and gamma-tocopherol, with the risk of gastric ade

Purpose: The purpose of this work was to evaluate the visibility of simulated lesions in 2D digital mammography (DM) and breast tomosynthesis (BT) images of patients. Methods: Images of the same women were acquired on both a DM system (Mammomat Novation, Siemens Healthcare, Erlangen, Germany) and a BT prototype system adapted from the same type of DM system. Using the geometrical properties of the

OBJECTIVES: To clarify whether the intensity of exposure to organic acid anhydrides (OAAs) is associated with the risk of sensitisation to these allergens. METHODS: The investigations were carried out in three different manufacturing plants (A, B, and C) where OAAs were used in the production of epoxy resins. Methyltetrahydrophthalic acid anhydride (MTHPA) was used in all three plants. The exposur

We present the red-listed plants and fungi that have been found in the central parts of the parish of Stenbrohult, southern Sweden. In the middle of the study areas Carl Linnaeus was born in 1707, and he spent his summers there until 1727. Of the 11 currently red-listed vascular plants (Gärdenfors 2000) that have been recorded since 1970 all occurred there also 300 years ago. Mosses, lichens and f

Purpose: To examine whether panretinal photocoagulation for severe non-proliferative retinopathy in type 1 diabetes patients could halt the progression of retinopathy with subsequent vitreous haemorrhages and visual impairment. Methods: During a 10-year follow-up study period of 344 type 1 diabetes patients, 81 subjects went through panretinal photocoagulation. Forty patients were treated for sev

BACKGROUND AND PURPOSE: To determine how a recently proposed clinical stroke subclassification corresponds to specific findings on computed tomography (CT) and magnetic resonance imaging (MRI) of the brain. METHODS: Two hundred twenty-eight patients with first-ever stroke were divided into four clinical subgroups: (1) total anterior circulation syndrome: both cortical and subcortical symptoms from

Popular Abstract in Swedish Variabilitet i ett läkemedels farmakokinetiska (hur ett läkemedel omsätts i kroppen) och farmakodynamiska (vilken effekt ett läkemedel har) egenskaper kan resultera i att olika individer som erhållit samma dos av ett läkemedel får olika effekter av läkemedel. Biverkningar eller utebliven effekt kan innebära allvarliga konsekvenser för den enskilda individen. VariabiliteVariability in pharmacokinetic and pharmacodynamic parameters between individuals can be due to intrinsic and extrinsic factors. In this thesis three different areas regarding sources of variability have been investigated. 1. Formulation properties as an extrinsic source of variability. Lipophilic substances often have poor oral bioavailability and high inter- and intraindividual variability. High

OBJECTIVE—To examine the effects of dipeptidyl peptidase-IV (DPP-4) inhibition on meal-related β-cell function and insulin sensitivity over 52 weeks in type 2 diabetes. RESEARCH DESIGN AND METHODS—In a 12-week core study, placebo (n = 51) or vildagliptin (n = 56; 50 mg OD) was added to metformin treatment (1.5–3.0 mg/day). A 40-week extension followed in 71 patients. Meal tests were performed at

Leptin is a key biological marker related to energy balance and development of diabetes and cardiovascular diseases. Its levels are increased in populations with a high degree of the metabolic syndrome. Life history of evolution has, however, largely taken place under the ecological context of hunting and gathering. In this study, we explored whether the first steps of transition to sedentary agri

In an attempt to identify novel susceptibility genes predisposing to early-onset diabetes (EOD), we performed a genome-wide scan using 433 markers in 222 individuals (119 with diabetes) from 29 Scandinavian families with ≥2 members with onset of diabetes ≤45 years. The highest nonparametric linkage (NPL) score, 2.7 (P < 0.01), was observed on chromosome 1p (D1S473/D1S438). Six other regions on chr

The Krüppel-associated Box Repressor Domain Can Trigger de Novo Promoter Methylation during Mouse Early Embryogenesis*□S Received for publication, July 18, 2007, and in revised form, September 24, 2007 Published, JBC Papers in Press, September 24, 2007, DOI 10.1074/jbc.M705898200 Maciej Wiznerowicz‡§1, Johan Jakobsson‡§2, Jolanta Szulc‡, Shunyao Liao‡§, Alexandra Quazzola‡§, Friedrich Beermann‡¶,

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/publication_in_journal_of_biological_chemistry.pdf - 2026-05-08

Checklista för uppdragsavtal Research Services Sophie Hyden Picasso Funding paths to excellence PLANNING THE ACADEMIC CAREER There are several career paths and profiles in academia, often combined or following upon each other in different stages of the career, requiring different types of skills. Research, teaching, collaboration, leadership and administration are all part of academic work and hav

https://www.staff.lu.se/sites/staff.lu.se/files/funding-paths-to-excellence.pdf - 2026-05-08

Minnesanteckningar från EDS Nordic User Group, Stockholm 2013-10-10 Plats: Stockholms universitetsbibliotek När: 2013-10-10 kl. 10-16 Närvarande: Egon Nilsson (Högskolan i Gävle, biblioteket), Mikael Arvidsson (Karlstad universitetsbibliotek), Mikael Blad (Karolinska universitetssjukhuset/Stockholms läns landsting), Jonas Barck (Linnéuniversitets bibliotek), Emma Nolin (Lunds universitetsbibliotek

https://www.ub.lu.se/sites/ub.lu.se/files/minnesanteckningar_fran_eds_nordic_user_group.pdf - 2026-05-08

SASNET News Bulletin 3_2016 Från: Lars Eklund lars.eklund@sasnet.lu.se Ämne: SASNET News Bulletin 3/2016 Datum: 14 oktober 2016 13:13 Till: Lars Eklund lars.eklund@sasnet.lu.se Lund 14 October 2016 SASNET key staff retires – two researcher positions announced On 31 October 2016, SASNET director Anna Lindberg will retire from her position after nine years; and two months later - on 31 December - de

https://www.sasnet.lu.se/sites/sasnet.lu.se/files/sasnet_news_bulletin_3_2016.pdf - 2026-05-08

PowerPoint-presentation Centrum för miljö- och klimatforskning, CEC Centrum för miljö- och klimatforskning, CEC, är en kombinerad fysisk och virtuell centrumbildning vid Naturvetenskapliga fakulteten på Lunds universitet. CEC bedriver forskning, utbildning och kommunikation om miljö- och klimatrelaterade frågor. 1 BESÖKSADRESS Ekologihuset Sölvegatan 37 i Lund Omsättning Mkr 70,3 Personal inklusiv

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/lu_cec_2018_4-3_svenska.pptx - 2026-05-08

Dnr V 2022/231 2022-02-17 1 (23) Redovisning av miljöledningsarbetet 2021 Lunds universitet Enligt förordning (2009:907) om miljöledning i statliga myndigheter Del 1 Miljöledningssystemet Basfakta Antal årsarbetskrafter: 7 380 Antal kvadratmeter lokalyta: 425 828 1. Är myndigheten miljöcertifierad? Nej. 2. Hur lyder myndighetens miljöpolicy? Lunds universitets policy för hållbar utveckling, senast

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2022-02/Lunds-universitets-miljoredovisning-2021.pdf - 2026-05-08