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Popular Abstract in Swedish Den äldre befolkningen i Sverige ökar i antal och med det ökar även antalet äldre med många sjukdomar som behöver läkemedel. Personer som är 75 år eller äldre utgör 9% av Sveriges befolkning men använder mer än 25% av alla läkemedel. I takt med att man blir äldre sker en del förändringar i kroppens funktioner som kan påverka effekten av läkemedel. De största förändringThe aim of this thesis was to investigate whether a structured and systematic approach on improving pharmacotherapy in the elderly (the LIMM-model) would lead to a more appropriate and accurate drug use in the elderly. The elderly use many drugs and are more prone to suffer from adverse drug reaction. It is therefore important to address the quality of their drug therapy. The first study presente

This study aimed at examine the number of planned and acute hospital admissions during 1 year among people 65+ and its relation to municipal care, outpatient care, multimorbidity, age and sex. Four thousand nine hundred and seven individuals having one or more admissions during 2001 were studied. Data were collected from two registers and comparisons were made between those having one, two and thr

In 2009, consistent with its objective to support and develop a European research infrastructure, the European Union (EU) created a neworganizational form for research collaborations: the European Research Infrastructure Consortium (ERIC). Since then, 21 different ERICs havebeen established in the EU Member States; the largest being the European Spallation Source (ESS).The financing of this ERIC i

While biometric authentication for commercial use so far mainly has been used for local device unlock use cases, there are great opportunities for using it also for central authentication such as for remote login. However, many current biometric sensors like for instance mobile fingerprint sensors have too large false acceptance rate (FAR) not allowing them, for security reasons, to be used in lar

Trade Unions are finding it increasingly challenging to appeal to employees and all trade unions alike are encountering new challenges to attract and retain members. Additionally a more diversified and educated labor market is creating demands for trade unions to better meet individual needs. The purpose of this study was to explore and analyze the role of branding in Unionen, the largest white-co

Objective: To gain deeper understanding of how teenage males view abortion, adolescent fatherhood, sexual behavior, and use of contraception. Method: We conducted six focus-group interviews with 17-year-old boys (n = 40). The interviews were tape-recorded, transcribed verbatim, and analyzed using manifest content analysis. Results: Adolescent fatherhood was considered to be a catastrophe and abort

Background: Acute myeloid leukemia (AML) patients have limited effect from T-cell-based therapies, such as PD-1 and CTLA-4 blockade. However, recent data indicate that AML patients with TP53 mutation have higher immune infiltration and other immunomodulatory therapies could thus potentially be effective. Here, we performed the transcriptional analysis of distinct T-cell subpopulations from TP53-mu

In the 20th century, Sweden distinguished itself as one of the most organized and participatory democracies in the world. But in the late 19th century the situation was much the opposite – Sweden had for Western Europe a low degree of suffrage, and low political participation. To explain the turnaround, this paper explores the evolution of a democratic political culture in the final third of the 1

The “alla kan blomstra” (“everyone can flourish”) vision is a framework adopted by Åland’s government that attempts to institutionalize integrative inner-outer transformation within governmental structures, policies and operations. It aims to merge conventional external approaches (e.g., traditional ecological services and technologies) with inner-led change (e.g., addressing collective perception

Historically, companies have communicated taxes as a burden, as the benefits provided by governments are not perceived to be in proportion to their payments. With sustainable development becoming central in many policy areas, new discourses including ‘fair’ or ‘sustainable’ tax have become omnipresent in public talk on taxes. This paper analyzes tax discourses in corporate annual reports within thHistorically, companies have communicated taxes as a burden, as the benefits provided by governments are not perceived to be in proportion to their payments. With sustainable development becoming central in many policy areas, new discourses including ‘fair’ or ‘sustainable’ tax have become omnipresent in public talk on taxes. This paper analyzes tax discourses in corporate annual reports within th

Background: Communication with patients and families about serious illness impacts quality of life and helps facilitate decision-making.Objective: To elucidate the pattern of communication about serious illness for patients who have died in an inpatient setting.Design: Three hundred patients from the Swedish Registry of Palliative Care 2015-2017 were randomly selected for manual chart review.Setti

Background: Depression and anxiety often reduce people’s ability to cope with everyday occupations. There is a lack of knowledge about such problems in people of working age with depression and anxiety. Aim: To describe which problems people with depression or anxiety disorders experience when performing everyday occupations and which occupations are affected. Materials and methods: Data based on

The objective of this study is to provide a better understanding of the potential of using Artificial Intelligence (AI) to improve Public Transport (PT), by reviewing research literature. The selection process resulted in 87 scientific publications constituting a sample of how AI has been applied to improve PT. The review shows that the primary aims of using AI are to improve the service quality o

Human rights statements on intersex characteristics distinguish legitimate “medically necessary” interventions from illegitimate normalizing ones. Ironically, this binary classification seems partially grounded in knowledge of anatomy and medical interventions; the very expertise that human rights statements challenge. Here, 23 European health professionals from specialist “disorder of sex developHuman rights statements on intersex characteristics distinguish legitimate “medically necessary” interventions from illegitimate normalizing ones. Ironically, this binary classification seems partially grounded in knowledge of anatomy and medical interventions; the very expertise that human rights statements challenge. Here, 23 European health professionals from specialist “disorder of sex develop

Drought in Australia has widespread impacts on agriculture and ecosystems. Satellite-based Fraction of Absorbed Photosynthetically Active Radiation (FAPAR) has great potential to monitor and assess drought impacts on vegetation greenness and health. Various FAPAR products based on satellite observations have been generated and made available to the public. However, differences remain among these d

Objective: A pay for performance programme was introduced in 2009 by a Swedish county with 1.6 million inhabitants. A process measure with payment linked to coding for medication reviews among the elderly was adopted. We assessed the association with inappropriate medication for five years after baseline.Design and setting: Observational study that compared medication for elderly patients enrolled