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Learning insertion of a Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) catheter : Is clinical experience necessary? A prospective trial

Background: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is an emerging and potentially life-saving procedure, necessitating qualified operators in an increasing number of centres. The procedure shares technical elements with other vascular access procedures using the Seldinger technique, which is mastered by doctors not only in endovascular specialties but also in trauma surg

Severe, life-threatening, and fatal chronic health conditions after allogeneic blood or marrow transplantation in childhood

Background: A comprehensive assessment of morbidity after allogeneic bone marrow transplantation (BMT) performed in childhood remains understudied. Methods: Seven hundred eighty-nine allogeneic BMT recipients who had survived ≥2 years after BMT performed between 1974 and 2014 at age <22 years and 690 siblings completed a 255-item survey self-reporting sociodemographics and chronic health condition

Psychosis in Systemic Lupus Erythematosus : Results From an International Inception Cohort Study

Objective: To determine, in a large, multiethnic/multiracial, prospective inception cohort of patients with systemic lupus erythematosus (SLE), the frequency, attribution, clinical, and autoantibody associations with lupus psychosis and the short- and long-term outcomes as assessed by physicians and patients. Methods: Patients were evaluated annually for 19 neuropsychiatric (NP) events including p

Synthesis and molecular structures of the 52-electron triiron telluride clusters [Fe3(CO)83-Te)22-diphosphine)] - Electrochemical properties and activity as proton reduction catalysts

Heating the 50-electron cluster [Fe3(CO)9 (μ3-Te)2] (1) with the diphosphines Ph2P-R-PPh2 [R = -CH2CH2- (dppe), Z-CH=CH- (dppv), 1,2-C6H4 (dppb), -CH2CH2CH2- (dpp), ferrocenyl (dppf), naphthalenyl (dppbn)] in benzene affords the 52-electron diphosphine-containing tellurium-capped triiron clusters [Fe3(CO)8 (μ3-Te)2 (κ2-diphosphine)] (diphosphine = dppe, dppv, dppb, dpp, dppf, dppnd) (2–7) in moder

Obesity and metabolic features associated with long-term developing diastolic dysfunction in an initially healthy population-based cohort

Background: Diastolic dysfunction (DD) is increasingly common. However, its metabolic determinants are poorly known. This study aims to determine which metabolic and inflammatory features predict DD in initially healthy adults. Methods: We prospectively analyzed the association between metabolic features and DD in 728 initially healthy adults aged 30–60 from Eastern France enrolled in the STANISLA

Black pepper-based beverage induced appetite-suppressing effects without altering postprandial glycaemia, gut and thyroid hormones or gastrointestinal well-being : A randomized crossover study in healthy subjects

Pleiotropic effects of spices on health, particularly on glucose metabolism and energy regulation, deserve further clinical investigation into their efficacy. The aim of the current study was to evaluate whether consumption of a black pepper-based beverage (BPB) preload containing 20 mg gallic acid equivalent (GAE) would exert any effect on postprandial glycaemia, appetite sensations, gut hormones

Soil and vegetation-atmosphere exchange of NO, NH3, and N2O from field measurements in a semi arid grazed ecosystem in Senegal

The alternating between dry and wet seasons and the consecutive microbial responses to soil water content in semiarid ecosystems has significant consequences on nitrogen exchanges with the atmosphere. Three field campaigns were carried out in a semi arid sahelian rangeland in Dahra (Ferlo, Senegal), two at the beginning of the wet season in July 2012 and July 2013, and the third one in November 20

Preoperative Coronary Anatomy Assessment with Echocardiography and Morbidity After Arterial Switch Operation of Transposition of the Great Arteries

In transposition of the great arteries (TGA), certain coronary patterns have been associated with major adverse events early after the arterial switch operation (ASO). We sought to determine the impact of preoperative echocardiographic (ECHO) diagnosis on the intra­ and postoperative morbidity. All patients with TGA born between June 2001 and June 2017 and who underwent ASO were reviewed. Data on

Progression of frailty and prevalence of osteoporosis in a community cohort of older women—a 10-year longitudinal study

Summary: In community dwelling, 75-year-old women followed 10 years, a frailty index was created at each of three visits. Frailty score increased by ~ 6–7% annually. A higher frailty score was equivalent to being 5–10 years chronologically older. Frailty was associated with low bone density and higher risk of dying. Introduction: To understand the distribution of frailty among a population-based s

Low plasma concentrations of apolipoprotein M are associated with disease activity and endothelial dysfunction in systemic lupus erythematosus

Background: Apolipoprotein M (apoM) is a 25-kDa apolipoprotein present in 5% of high-density lipoprotein (HDL) particles. It is suggested to be anti-atherogenic and to play a key role in sustaining endothelial barrier integrity. SLE patients have increased cardiovascular disease risk, and we aimed to investigate if apoM levels reflect endothelial function in SLE. Since apoM plasma levels decrease

Molecular subtypes applied to a population-based modern cystectomy series do not predict cancer-specific survival

Objectives: To investigate the preoperative prognostic value of molecular subtypes in relation to clinical information, histopathological findings, and molecular markers for patients with bladder cancer treated with radical cystectomy. Patients and methods: After standard preoperative staging, a population-based cohort of 519 patients underwent radical cystectomy between 2006 and 2011. Following

Peripheral artery disease and outcomes in patients with acute myocardial infarction

im To describe the population of patients with previously diagnosed peripheral artery disease (PAD) experiencing a myocardial infarction (MI) and to investigate 1-year major adverse cardiac events (MACE: all-cause mortality, reinfarction, stroke and heart failure hospitalisation) following MI.Background MI patients with PAD constitute a high-risk population with adverse cardiac outcomes. Contempor

Genetic variants of filaggrin are associated with occupational dermal exposure and blood DNA alterations in hairdressers

Hairdressers are exposed to high levels of chemicals, including possible carcinogens. For dermal exposure, the skin protects against the uptake of chemicals and the protein filaggrin (encoded by FLG) has a key role in skin barrier function. This study investigated if variants of FLG previously linked to impaired skin barrier function, i.e. null mutations and copy number variation (CNV) alleles (CN

Helicobacter pylori and CagA seropositivity and its association with gastric and oesophageal carcinoma.

Objective. Helicobacter pylori infection is an established risk factor for non-cardia gastric adenocarcinoma. Infection with H. pylori strains harbouring the cagA pathology island may augment this association. H. pylori infection may at the same time reduce the risk for oesophageal carcinoma. However, prospective data on the association between CagA seropositivity and gastric or oesophageal carcin

Occurrence and prognostic significance of ventricular arrhythmia is related to pulmonary function: a study from "men born in 1914," Malmo, Sweden

BACKGROUND: Reduced lung function has been associated with increased rates of myocardial infarction. Whether the occurrence and prognostic significance of ventricular arrhythmia is related to lung function is largely unknown. METHODS AND RESULTS: We performed a population-based study of 68-year-old men without a history of stroke or myocardial infarction; 402 men participated. Mortality and corona

No improvement in injection frequency or in visual outcome over time in two cohorts of patients from the same swedish county treated for wet age-related macular degeneration

Background: Although ranibizumab has been used for the treatment of wet age-related macular degeneration (AMD) since 2007, real-world studies still report undertreatment resulting in a less favorable visual outcome. In this study, two different time cohorts of patients treated with ranibizumab for wet AMD in routine care were analyzed to observe whether there was a change over time regarding visua

Timing and speed of migration in male, female and juvenile Ospreys Pandion haliaetus between Sweden and Africa as revealed by field observations, radar and satellite tracking

Breeding Ospreys were studied in southern Sweden and 13 birds were tracked by satellite telemetry on autumn migration to the African wintering grounds. This was supplemented with studies of migrating birds at Falsterbo and radar trackings From southern Sweden. Females generally left the nest site 2-3 weeks ahead of males and juveniles. Among males, failed bleeders migrated significantly earlier th

Resedabi Hylaeus signatusNT (Panzer) (Hymenoptera: Colletidae) påträffat i Botaniska trädgården i Lund.

A first find and a few subsequent observations of the oligolectic Large Yellow-Face Bee Hylaeus signatusNT (Panzer) were made during the second half of August in the Botanical Garden of Lund, province of Scania, Southern Sweden. About a dozen of specimens were attracted to a stand of Reseda luteola, one of its primary pollen sources. This bee is one of several newcomers among solitary bees in Swed

HIV-1 transmission networks in high risk fishing communities on the shores of Lake Victoria in Uganda : A phylogenetic and epidemiological approach

Background: Fishing communities around Lake Victoria in sub-Saharan Africa have been characterised as a population at high risk of HIV-infection. Methods: Using data from a cohort of HIV-positive individuals aged 13–49 years, enrolled from 5 fishing communities on Lake Victoria between 2009–2011, we sought to identify factors contributing to the epidemic and to understand the underlying structure