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The european hematology association roadmap for european hematology research : A consensus document

The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will hel

Kinetics and Mechanism for Reduction of Gold(III) Complexes by Dimethylsulfide

The reactions between trans-[Au(CN) 2 X 2 ] - (X = Cl or Br) and Me 2 S have been studied by conventional and high-pressure stopped-flow spectrophotometry in acidic aqueous solution containing 10% (w/w) methanol. The overall stoichiometry Au III ∶Me 2 S is 1∶(1.0 ± 0.1) in agreement with the reaction: trans-[Au(CN) 2 X 2 ] - + Me 2 S + H 2 O → [Au(CN) 2 ] - + Me 2 SO + 2H + + 2X - . Initial rapid

Acoustophoresis enables the label-free separation of functionally different subsets of cultured bone marrow stromal cells

Culture-expanded mesenchymal stromal cells (MSCs) are promising candidates for clinical cell-based therapies. MSC products are heterogeneous and we therefore investigated whether acoustophoresis, an ultrasound-based separation technology, could be used for the label-free enrichment of functionally different MSC populations. Acoustophoresis uses an ultrasonic standing wave in a microchannel which d

Temporal trends and regional disparity in rheumatoid arthritis and gout hospitalizations in Sweden, 1998-2015

Hospitalization is an important component of rheumatoid arthritis (RA) and gout economic burden. This study aimed to assess temporal trends and regional disparities in RA and gout hospitalizations among people aged ≥ 20 years in Sweden during 1998-2015. Data on hospital admissions with a principal diagnosis of RA or gout were collected from the National Patient Register. Age-standardized hospitali

No relation between biomarkers at age 47-49 and aortic diameter after 14-19 years of follow-up - a population-based study

BACKGROUND: Biomarkers reflecting diverse pathophysiological pathways may play an important role in the pathogenesis of abdominal aortic aneurysm (aortic diameter ≥30 mm, AAA), levels of many biomarkers are elevated and correlated to aortic diameter among 65-year-old men undergoing ultrasound (US) screening for AAA.PROBANDS AND METHODS: To evaluate potential relationships between biomarkers and ao

Whole System in the Room : Toward Systems Integration in Healthcare

How might systems integration be furthered in healthcare? The paper addresses this by exploring critically the potentials of appreciative inquiry for accelerating systems integration through a large group intervention. We analyze a one-day dialog workshop to get “the whole system in the room” to improve cancer care in a regional health authority in south west Sweden. Seeing systems integration as

Hur kuratorn balanserar känslor och byråkrati : Blanketters betydelse i vårdmötet

Artikeln fokuserar på hälso- och sjukvårdskuratorns arbete med att å ena sidan bemöta de känslor som barn och familjer kan känna efter att barnet diagnostiserats med den kroniska sjukdomen diabetes, å andra sidan han-tera olika byråkratiska processer som ska sörja för att barnets vårdbehov tillgodoses i familjens nya vardag. Arbetet riktas mot två olika världar som är inbördes beroende av varandraThe article focuses on the work of clinical social workers who, on the one hand, respond to the emotions that children and families experience after the child is diagnosed with the chronic disease diabetes, on the other hand, deal with various bureaucratic processes aimed at ensuring that the child’s medical needs are met in the family’s new life. The work is directed towards two different worlds

Kinetic energy of left ventricular blood flow across heart failure phenotypes and in subclinical diastolic dysfunction

BACKGROUND: Kinetic energy (KE) of intracardiac blood flow reflects myocardial work spent on accelerating blood and provides a mechanistic window into diastolic filling dynamics. Diastolic dysfunction may represent an early stage in the development of heart failure (HF). Here we evaluated the hemodynamic effects of impaired diastolic function in subjects with and without HF, testing the hypothesis