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Background. The diagnostic work-up and treatment of patients with neuroendocrine neoplasms (NENs) has undergone major recent advances and new methods are currently introduced into the clinic. An update of the WHO classification has resulted in a new nomenclature dividing NENs into neuroendocrine tumours (NETs) including G1 (Ki67 index <= 2%) and G2 (Ki67 index 3-20%) tumours and neuroendocrine car
The problem of integrating the Camassa-Holm equation leads to the scattering and inverse scattering problem for the Sturm-Liouville equation -u '' + 1/4 u = lambda wu, where w is a weight function which may change sign but where the left-hand side gives rise to a positive quadratic form so that one is led to a left-definite spectral problem. In this paper the spectral theory and a generalized Four
In this Letter we analyze the relation between the triple-pomeron and Good-Walker formalism's for diffractive excitation in DIS and hadronic collisions. In both approaches gap events are interpreted as the shadow of absorption into inelastic channels. We here argue that the two formalisms are just different views of the same phenomenon. We first demonstrate how this relation works in a simple toy
Applications of immobilized biocatalysts in both research and industry require highly active catalysts, preferably at a low cost. In this study, cryogels with high catalyst density were produced through cryostructuration of whole Escherichia coli (E.coli) cells. Prepared cryogels are macroporous materials composed of metabolically active cells crosslinked to each other via polymeric structures. Di
This paper presents a new method, based on constraint programming, for modeling and solving scheduling and instruction selection for processors extended with a functionally reconfigurable cell fabric. Our method models parallel reconfigurable architectures, the selection of application specific computational patterns and application scheduling. It takes also into account architectural constraints.
Context: This review focuses on the prevention and management of complications following radical cystectomy (RC) for bladder cancer (BCa). Objective: We review the current literature and perform an analysis of the frequency, treatment, and prevention of complications related to RC for BCa. Evidence acquisition: A Medline search was conducted to identify original articles, reviews, and editorials a
For small deformations a crack/interface model that considers general 3D normal and shear loading is proposed. It involves elasticity, plasticity and damage and it is thermodynamically based. An essential feature of the model is its consistency with the concepts behind the fictitious crack model. In particular, no crack deformation occurs before the crack is initiated and when a crack has just bee
Popular Abstract in Swedish Diabetes är en endokrin sjukdom som också kallas sockersjuka. Den kännetecknas av förhöjda mängder socker i blodet. Halten av socker i blodet, blodsockret, styrs av hormonet insulin, som produceras av β-celler i Langerhanska öar i bukspottskörteln. När insulin frisätts stimuleras muskler, fettväv och lever till att ta upp glukos ur blodet och lagra det. På så sätt sänksType 2 Diabetes (T2D) prevalence is growing to pandemic proportions worldwide. The link between genotype, environment and β-cell function is still being investigated. I have devoted the work presented in this thesis to attempt to elucidate the coupling of β-cell metabolism to insulin secretion and to look for casual mechanisms underlying metabolic alterations disturbing insulin secretion. In paper
More reliable and faster prediction methods are needed to interpret enormous amounts of data generated by sequencing and genome projects. We have developed a new computational tool, PON-P2, for classification of amino acid substitutions in human proteins. The method is a machine learning-based classifier and groups the variants into pathogenic, neutral and unknown classes, on the basis of random f
Asteroseismology has the capability of precisely determining stellar properties that would otherwise be inaccessible, such as radii, masses, and thus ages of stars. When coupling this information with classical determinations of stellar parameters, such as metallicities, effective temperatures, and angular diameters, powerful new diagnostics for Galactic studies can be obtained. The ongoing Stromg
A series of photosensitizers for NiO-based dye-sensitized solar cells is presented. Three model compounds containing a triphenylamine donor appended to a boron dipyrromethene (bodipy) chromophore have been successfully prepared and characterised using emission spectroscopy, electrochemistry and spectroelectrochemistry, to ultimately direct the design of dyes with more complex structures. Carboxyli
A capture-mark-recapture study on the threatened saproxylic beetle Lucanus cervus was carried out in a chestnut (Castanea sativa) woodland located in northern Italy, using visual encounter surveys (VES) as well as aerial flight interception traps and pitfall traps (PT), both of which were baited with different odour lures. In total, 111 males and 25 females were captured, and VES was by far the mo
Abstract in UndeterminedFaster-than-Nyquist (FTN) signaling is a method of improving bandwidth efficiency by transmitting information beyond Nyquist's orthogonality limit for interference free transmission. Previously have theoretically established that FTN can provide improved bandwidth efficiency. However, this comes at the cost of higher decoding complexity at the receiver. Our work has evaluat
Arid and semiarid Middle Eastern countries generally, and Syria in particular, face serious water shortage problems and challenges with water sustainability. Climate change, population growth, and economic development play a major role in decreasing available water resources per capita. This, in turn, has great impact on domestic, agricultural, and industrial water use. In this study, marginal and
Popular Abstract in Swedish Idag tar de flesta för givet att man när och var som helst kan komma åt sin e-post, ladda upp bilder till Facebook eller söka kunskap på Wikipedia från sin mobiltelefon eller dator. Den trådlösa teknologi som gjort detta möjligt har utvecklats oerhört det senaste årtiondet, men behöver utvecklas ännu mer för att möta det ökande behovet av trådlös kommunikation. I dennaThe traffic in wireless networks has been showing an exponential growth over the last decade. In order to meet the demand, and support a continuation of this growth, the scarce radio resources need to be efficiently used. The use of multiple antenna (MIMO) systems and iterative (turbo) receivers has significantly improved the realizable system performance. Still, many challenges exist in the devel
This paper discusses importance of a strategic planning and design process when developing long-term space exploration missions both robotic and manned. The discussion begins with reviewing current and/or traditional international perspectives on space development at the American, Russian and European space agencies. Some analogies and comparisons will be drawn upon analysis of several internation
The normal approach to digital control is to sample periodically in time. Using an analog of integration theory we can call this Riemann sampling. Lebesgue sampling or event based sampling is an alternative to Riemann sampling. It means that signals are sampled only when measurements pass certain limits. In this paper it is shown that Lebesgue sampling gives better performance for some simple syst
Using DTT and iodoacetamide as a novel irreversible method to inhibit endogenous violaxanthin de-epoxidase, we found that violaxanthin could be converted into zeaxanthin from both sides of the thylakoid membrane provided that purified violaxanthin de-epoxidase was added. The maximum conversion was the same from both sides of the membrane. Temperature was found to have a strong influence both on th
The max-bisection and min-bisection problems are to find a partition of the vertices of a graph into two equal size subsets that, respectively, maximizes or minimizes the number of edges with endpoints in both subsets. We design the first polynomial time approximation scheme for the max-bisection problem on arbitrary planar graphs solving a long-standing open problem. The method of solution involv
