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Phosphatidylethanol (PEth) represents a group of glycerophospholipid homologues where ethanol by phospholipase D has been bound at the position that normally contains an amino-alcohol. Since the formation of PEth is specifically dependent on ethanol, the diagnostic specificity of PEth as an alcohol biomarker is theoretically 100%. The half-life of PEth in blood is approximately 4 days. The amount
Abstract is not available
This study examined emotional influences on the hypothesized event-related potential (ERP) correlates of familiarity and recollection (Experiment 1) and the states of awareness (Experiment 2) accompanying recognition memory for faces differing in facial affect. Participants made gender judgments to positive, negative, and neutral faces at study and were in the test phase instructed to discriminate
The n-CoDeR recombinant antibody gene libraries are built on a single master framework, into which diverse in vivo-formed complementarity determining regions (CDRs) are allowed to recombine. These CDRs are sampled from in vivo-processed and proof-read gene sequences, thus ensuring an optimal level of correctly folded and functional molecules. By the modularized assembly process, up to six CDRs can
Questions concerning the human–nature relationship have received attention both within contemporary Christianity and Buddhism. Since the twentieth century an interesting and fruitful dialogue has been going on between the two religions. This article describes and discusses possible themes for a Buddhist–Christian dialogue on issues of environmental philosophy. The theoretical starting-point is the
Investigators in modern molecular/genetic epidemiology studies commonly analyze data on a vast number of candidate genetic markers. In such situations, rather than conventional estimation of effects (odds ratios), more accurate estimation methods are needed. The author proposes consideration of empirical Bayes and semi-Bayes methods, which yield 'adjustments for multiple estimations' by shrinking
Population-based cancer registries are widely used to provide key information about cancer incidence, survival, determinants of progression and clues about pathogenesis. To substantially expand the limited data on diagnostic accuracy and completeness for lym-phoproliferative (LP) tumors in such databases, we conducted a retrospective investigation of close to 1,000 cases diagnosed during 4 decades
This paper focuses on leakage reduction at architecture and arithmetic level. A methodology for considerable reduction of the static power consumption is shown. Simulations are done in a typical 130 nm CMOS technology. Based on the simulation results, the static power consumption is estimated and compared for different filter architectures. Substantial power reductions are shown in both FIR-filter
Purpose: To investigate the measures of validity for selective or population screening of the time-domain Stratus and the spectral-domain Cirrus Optical Coherence Tomography (OCT) imaging techniques in a population-based sample and in clinical glaucoma patients at different stages of glaucoma. Patients and methods: A random sample of 307 subjects living in two rural areas in southern Sweden, and a
ABSTRACT: BACKGROUND: Neuroblastoma (NB) is the most common extracranial solid tumour of childhood. Several genomic imbalances correlate to prognosis in NB, with structural rearrangements, including gene amplification, in a near-diploid setting typically signifying high-risk tumours and numerical changes in a near-triploid setting signifying low-risk tumours. Little is known about the temporal seq
Lyapunov methods and density functions provide dual characterizations of the solutions of a nonlinear dynamic system. This work exploits the idea of combining both techniques, to yield stability results that are valid for almost all the solutions of the system. Based on the combination of Lyapunov and density functions, analysis methods are proposed for the derivation of almost input-to-state stab
Fabrication and optical characterization of single-mode polymeric embedded waveguides are performed. A specific material combination (SU-8 2005 as core and the modified SU-8 mr-L 6050XP as cladding) is chosen in order to obtain a small refractive index difference for single-mode propagation combined with the conventional fabrication method UV lithography to facilitate the integration of different
Objective This study examines whether neighbourhood deprivation increases the risk of giving birth to a small for gestational age (SGA) infant, after accounting for individual-level maternal socioeconomic characteristics. Design An open cohort of women, aged 20-44 years, was followed from 1 January 1992 through 31 December 2004 for first singleton births. The women's residential addresses during t
The combined contribution to highway safety of pavement surface and geometric design indicators is not well investigated due to the complexity of data collection and high time variability of pavement surface conditions. Introduction of high efficiency equipment for comprehensive road surveys is mitigating this issue, expanding possibilities of data integration. In this framework, the present study
In February, 2020, the European Commission published a white paper on artificial intelligence (AI) as well as an accompanying communication and report. The paper sets out policy options to facilitate a secure and trustworthy development of AI and considers health to be one of its most important areas of application. We illustrate that the European Commission's approach, as applied to medical AI, p
We consider the pebble game on DAGs with bounded fan-in introduced in [Paterson and Hewitt '70] and the reversible version of this game in [Bennett '89], and study the question of how hard it is to decide exactly or approximately the number of pebbles needed for a given DAG in these games. We prove that the problem of deciding whether s pebbles suffice to reversibly pebble a DAG G is PSPACE-comple
At a large tunnel project in Southern Sweden a number of geoelectrical and IP imaging were carried out. The tunnel is drilled through a horst with a complex geology which includes fractures, high water content and weathered zones. The measurements where carried out to compile a geologic model to use in the further planning of the project. The resistivity and IP complements each other very well sin
