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TFPI-2 protects against gram-negative bacterial infection

Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad antimicrobial activity. In the present study, we describe a previously unknown antimicrobial mode of ac

NPOs and private governance forms for football clubs : towards a blended model

Purpose: This study explores the relationship between governance model – private organisations vs non-profit organisations (NPOs) – and performance in football clubs. Design/methodology/approach: The study is a comparative case study of two football clubs with different governance models: Malmö FF, which is an NPO, and Bologna FC, which is a privately owned club. Findings: The results show that bo

Defining extended half-life rFVIII-A critical review of the evidence

Introduction: Recent haemophilia treatment advances include new recombinant FVIII (rFVIII) products with improved pharmacokinetic (PK) properties that aim to reduce the burden of prophylaxis. These treatments are commonly referred to as extended half-life rFVIII products (EHL rFVIII). There is no uniform definition of what constitutes an EHL rFVIII. Such a definition would help physicians, patient

Plasmodium falciparum transmission based on merozoite surface protein 1 (msp1) and 2 (msp2) gene diversity and antibody responses in Ibadan, Nigeria

Background: Nigeria is a major contributor to the global malaria burden. The genetic diversity of malaria parasite populations as well as antibody responses of individuals in affected areas against antigens of the parasite can reveal the transmission intensity, a key information required to control the disease. This work was carried out to determine the allelic frequency of highly polymorphic Plas

Novel peptide ligand with high binding capacity for antibody purification

Small synthetic ligands for protein purification have become increasingly interesting with the growing need for cheap chromatographic materials for protein purification and especially for the purification of monoclonal antibodies (mAbs). Today, Protein A-based chromatographic resins are the most commonly used capture step in mAb down stream processing; however, the use of Protein A chromatography

C-terminal TFPI-1-derived peptides: their evolutionary host defense functions

Antimicrobial peptides (AMPs) are evolutionarily ancient molecules. They are essential innate immune response molecules that protect organisms from invading pathogens. Tissue factor pathway inhibitors (TFPI-1 and TFPI-2) C-terminal derived peptides exert host defense mechanisms against microbes. Studies showed that in human plasma, C-terminal TFPI-1 and -2 derived peptides mediate bacterial killin

Workshop: Art, research, and moral agency : Research-based dramatized film as a tool to foster solidarity and a catalyst for social change

Aim of the workshop: We invite colleagues to share experiences on cross-fertilization of art and social work research and to discuss how research-based art can serve as a catalyst for social change. Also, the workshop will give hands on knowledge on how to work with the method “deepened film talks”. Background: In a research project focusing moral stress and moral agency in social work, concrete s

Så kan man använda militära strategier mot cancer – Vetenskap och Hälsa

Så kan man använda militära strategier mot cancer – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Så kan man använda militära strategier mot cancer 2017-02-02 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Kan militära strategier användas som inspiration fö

https://www.vetenskaphalsa.se/sa-kan-man-anvanda-militara-strategier-mot-cancer/ - 2026-05-12

The visfatin (PBEF1) G-948T gene polymorphism is associated with increased high-density lipoprotein cholesterol in obese subjects.

The newly discovered adipokine visfatin has been hypothesized to be related to obesity and insulin resistance. In this study, we investigate if the 2 single nucleotide polymorphisms rs4730153 and G-948T are associated with obesity and/or related traits and whether they influence the messenger RNA (mRNA) levels of PBEF1 (originally the abbreviation for pre-B-cell colony-enhancing factor 1) in visce

Certainty and systematicity of practice-derived evidence matter for its relative importance in professional decision-making : Survey results on the role of proven experience in Swedish medicine, nursing, OT, dentistry, and dental hygiene

High-quality healthcare decisions need to balance input from science and clinical practice. When two sources of evidence — such as scientific and practice-derived evidence — are compared, integrated, or need to stand-in for one another, they need to be comparable on similar dimensions. Since 1891, Swedish physicians have been operating under a legal requirement to base their healthcare decisions oBackgroundHigh-quality healthcare decisions need to balance input from science and clinical practice. When two sources of evidence — such as scientific and practice-derived evidence — are compared, integrated, or need to stand-in for one another, they need to be comparable on similar dimensions. Since 1891, Swedish physicians have been operating under a legal requirement to base their healthcare d

Global Answer: Social Work and Human Mobility

Comparative studies on local government and good social work practices in the euro-mediterranean region EU-projektet "Global Answer: Social Work and Human Mobility" är ett internationellt och sektorsövergripande nätverk av komparativ och kollaborativ forskning och praktik. Syftet är att identifiera, analysera och sprida goda exempel på socialt arbete i relation till människors mobilitet i de europ

https://www.soch.lu.se/global-answer-social-work-and-human-mobility - 2026-05-13

Design for Serviceability - A probabilistic approach

Popular Abstract in Uncoded languages A modern tartószerkezeti szabványok általában két fő követelményt támasztanak a tartószerkezetekekkel, illetve szerkezeti elemekkel szemben. Az egyik a tönkremenetellel szembeni biztonsághoz, míg a másik a használhatósághoz kapcsolódik. A szerkezeti használhatóság a tartószerkezet azon képessége, hogy tervezett szerepét élettartams során folyamatosan betöltse.In many design situations the acceptable performance of structures is defined by serviceability requirements. To estimate the probability of serviceability failure three main design aspects should be considered: (1) the relevant exposures, (2) the structural response and (3) the performance criteria. This thesis presents background information and new findings on structural serviceability related

Pauline Mattsson

Universitetslektor Kontaktinformation E-post: pauline [dot] mattsson [at] fek [dot] lu [dot] seOrganisation Forskningspolitik Hämtställe: 10 WebbplatsPauline Mattssons profil i Lunds universitets forskningsportalAndra roller Biträdande universitetslektor CIRCLE Publikationer Visar av publikationer. Sorterade efter år och sen titel. Filtrera efter typ AllaArtikel i tidskriftDel av eller Kapitel i b

https://www.ehl.lu.se/pauline-mattsson - 2026-05-13

PAP treatment in patients with OSA does not induce long-term nasal obstruction

We hypothesized that positive airway pressure treatment would induce nasal obstruction and decrease nasal cavity due to mucosal swelling. We further hypothesized that subjective and objective nasal obstruction at baseline would negatively affect positive airway pressure adherence. A total of 728 patients with sleep apnea were investigated in the Icelandic Sleep Apnea Cohort at baseline and 2 years

Total adiponectin does not predict cardiovascular events in middle-aged men in a prospective, long-term follow-up study

Aim. Plasma total adiponectin is a marker of insulin resistance, but its role in predicting cardiovascular events is unclear. We aimed to investigate the role of adiponectin as a predictor of cardiovascular risk in middle-aged men, and to describe the association between adiponectin and glucose metabolism. Methods. In this population-based prospective study of middle-aged men (n=3885), total adipo

Does long-term smoking affect aortic stiffness more in women than in men?

Smoking is a well-known risk factor for cardiovascular disease, although understanding of the pathophysiological mechanism is incomplete. The effect of heavy smoking, for more than 20 years and of 20 cigarettes per day, on aortic stiffness was studied in women (n = 23, age range 43-61 years) and men (n = 21, age range 43-61 years) who smoked but were otherwise healthy and compared with a healthy r