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Objective: This study primarily aimed to comprehensively characterize the neurological, neuroradiological and neurocognitive profiles, as well psychiatric features of individuals with Spinocerebellar Ataxia Type 34 (SCA34) associated with pathogenic variants in the ELOVL4 gene. Secondarily, we investigated the relationship between neurocognitive functions and cerebellar morphology in individuals w

Baltoskandien utgör en del av paleokontinenten Baltica, vilken mestadels var täckt av ett grunt epeiriskt hav under den ordoviciska tidsperioden (ca 485,5–444 Ma). Detta uråldriga hav efterlämnade en tunn lagerföljd av sedimentära bergarter. Under tidig–mellanordovicium (ca 485,5–457,5 Ma) befann sig Baltica vid tempererade breddgrader på södra halvklotet och kallvattenkarbonater bildades över stoThe Baltoscandian region forms part of the paleocontinent Baltica, which was largely covered by a shallow epeiric sea throughout much of the Ordovician (c. 485.5–444 Ma). This ancient sea is today recorded by a thin succession of sedimentary rocks. During the Early–Middle Ordovician (c. 485.5–457.5 Ma), Baltica was situated in mid-latitudes on the southern hemisphere and cool-water carbonates form

A dedicated reconstruction algorithm to find decay vertices in the ATLAS muon spectrometer is presented. The algorithm searches the region just upstream of or inside the muon spectrometer volume for multi-particle vertices that originate from the decay of particles with long decay paths. The performance of the algorithm is evaluated using both a sample of simulated Higgs boson events, in which the

Popular Abstract in Swedish Dödligheten i skador i Sverige har under de senaste årtiondena minskat, en minskning som idag dock har planat ut. Antalet dödade i transportolyckor och i arbetsplatsolyckor i Sverige har minskat under de senaste 40 åren vilket kan ses som ett resultat av ett effektivt säkerhetsarbete. När det gäller fallolyckor så har däremot andelen som dör av sina skador ökat markant Injuries are often associated with long-term suffering and lowered functioning, and personal injuries impose a huge burden on medical care and health services in addition to the costs associated with impaired functional ability. Each year in Sweden, falling accidents are experienced by a third of those aged 60 or over and half of those aged 80 or over, while injuries from traffic accidents still a

Popular Abstract in Swedish Avfallshantering ägnas nuförtiden ett ökande intresse. Detta verk syftar till att analysera hur vanligt förekommande företagsekonomiska modeller och metoder liksom principen om att förorenaren betalar (The "Polluter-Pays Principle" (PPP)), generellt kan appliceras på management av avfallshantering och specifikt på segregering av olika avfallsfraktioner i syfte att medgeIncreased attention is nowadays devoted to waste management. The objective of this work is to analyse how commonly known business economic models and methods, as well as the Polluter-Pays Principle, can be applied to waste management in general and to waste fractionation in particular, so as to facilitate environmental optimisation of industrial and construction waste fractionation. In discussing

The introduction of the laparoscope was a milestone within gynecologic surgery. Despite evidence of better perioperative outcome compared to laparotomy, laparoscopy is mostly performed for less advanced surgical procedures and the uptake of laparoscopic hysterectomy has been slow. An effort to preserve the clinical benefits of laparoscopic surgery and facilitate the performance of more advanced su

Popular Abstract in Swedish Denna avhandling berör storskalig genetisk variation och fylogeni hos arterna i växtsläktet Alisma (svaltingar). Den naturliga utbredningen för detta släkte av vatten- eller sumpväxter inskränker sig till norra halvklotets tempererade områden. Den vanligaste arten i större delen av Europa är Alisma plantago-aquatica (svalting eller kranssvalting som den ibland också kalIn the present thesis the phylogeny and patterns of genetic diversity of the plant genus Alisma (Alismataceae) were investigated by means of genetic markers (RAPDs, allozymes, and ITS and trnL sequences). Additionally, morphological studies were carried out in paper IV. All species in the genus were found to be closely related to each other and two major groups of diploid taxa were found: one cont

Innovation is an interactive learning process that is facilitated naturally by geographic proximity. Innovation intermediaries can serve as an extra catalyst to and facilitator of interaction and collaboration. With today’s more globalized knowledge and innovation landscape, companies and research organizations seek complementary competencies and partners with whom they can collaborate on a much b

The starting point of this study is the striking similarities between late modern notions of anthropogenic climate change and premodern ideas about divine punishment. In both these cases the occurrence of future disasters have been directly linked to the moral behavior of the endangered. What threatens to befall man is considered to be his own fault. Hence urgent calls have been made for each and

Telecommunications industries are investing tremendously to meet the ever-increasing demands for higher data rates and capacity. In particular to develop standardization for 5G, which is expected around 2020. The existing spectrum for traditional mobile networks is limited to highly occupied bands at microwave frequencies below 6 GHz. It is expected that 5G will use millimeter-waves to enable high

Popular Abstract in Swedish Geografisk fördelning av inomartsvariation i vittspridda Euroasiska skogsväxter Torbjörn Tyler Sammanfattning av författaren's doktorsavhandling Inledning Arter's utbredningar bestäm's inte bara av omvärldsfaktorer som klimat och jordmån utan även av de möjligheter det givit's dem att sprida sig. För att sprida sig över stora geografiska områden kräv's tid och i en väMany woodland plant species have huge distribution areas covering large parts of the Eurasian continent including areas that were glaciated during the last glacial period. In the present thesis, the geographic distribution of variation within such species is investigated and discussed in relation to glacial survival and post-glacial migration, dispersal ability, breeding system and levels of gene-

Technology Note Confocal Airyscan The Airyscan Detector from ZEISS Confocal Imaging with Improved Signal-to-Noise Ratio and Superresolution Technology Note 2 The Airyscan Detector from ZEISS Confocal Imaging with Improved Signal-to-Noise Ratio and Superresolution Author: Joseph Huff, Wolfgang Bathe, Dr. Ralf Netz Dr. Tiemo Anhut, Dr. Klaus Weisshart Carl Zeiss Microscopy GmbH, Germany Date: July 2

https://www.ludc.lu.se/sites/ludc.lu.se/files/en_wp_airyscan-detector.pdf - 2026-06-22

COSB55 Course Outline 2022 CÖSB20: Contemporary Japanese Society, 7.5 Credits Fall Semester 2022 2022-11-30 – 2022-01-15 Venue: Zoom Course Director: Paul O’Shea E-mail: paul.oshea@ace.lu.se Office hours: By appointment Course Content This course examines contemporary Japanese society, focusing on issues such as politics, pop culture, demographic change and environment. We go beyond media stereoty

https://www.ace.lu.se/sites/ace.lu.se/files/2022-10/COSB55%20Course%20Outline%202022.pdf - 2026-06-22

Popular Abstract in Chinese 概括 II型糖尿病的發展趨勢在全世界範圍內非常迅速。我國目前有超過九千萬II型糖尿病患者，另外有大量血糖不正常的糖尿病高危人群。其中只有三成病人對自己的病情有所了解。II型糖尿病的病人與日俱增。 說到糖尿病，自然就會想到胰島素，以及血糖和胰島素的關系。胰島素是人體中非常重要的激素（荷爾蒙）。人體所需要的糖分主要是從食物中的澱粉類食物（米飯，面食）中來的，肉類也含有一部分的糖分。糖分從小腸吸收進入血液循環。胰島素的功能是讓身體細胞把血液中的糖分吸收進入細胞（比如肌肉細胞）加以使用，同時降低血液中的血糖成份。如果胰島素分泌不足，或者人體細胞對胰島素的敏感性降低會引起血糖升高，長期高血糖會損害血管和臟器的健康，最終導致糖尿病並發癥的發生。糖尿病並發癥是一種常見的慢性並發癥，後果相當嚴重，足部壞疽、腎功能衰竭、尿毒癥、視力模糊不清、失明、腦血Type 2 diabetes mellitus (T2DM) is a heterogeneous disease with a multifactorial aetiology comprising of genetic and environmental factors. The common variant most highly associated with T2DM known to date is a SNP rs7903146 in the TCF7L2 gene. However, the role TCF7L2 plays in the development of T2DM was unclear. Clinical, animal and in vitro studies have revealed an association of the risk T-all

Den ekonomiska brottsligheten har fått en allt mer markant roll i dagens rättssamhälle. Brottslighet som förövas inom bolag blir allt mer av ett samhällsproblem, inte minst när det gäller brottslighet i organiserad form. Av allt större vikt blir då hur man ställer de personer som begår brott inom ett bolag till ansvar för sina gärningar. Utifrån detta syfte har principen om företagaransvar tillkEconomic crime has played an increasingly significant role in our modern society. Crime perpetrated within companies are becoming more of a social problem, not least when it comes to organized crime. It has become of greater importance, how to hold the persons who commit crimes within a company accountable for their deeds. Based on this purpose, certain principles for criminal responsibility with

Background: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by tau and amyloid brain pathology. With the gradual degeneration of neurons, cognitive symptoms will arise and the affected individual will eventually develop AD dementia. The neuropathologic hallmarks of AD have been observed also in cognitively healthy individuals, which has led to the assumption that the disorde

Nik-related kinase: A New IL-10 Regulator Our body is constantly exposed to microscopic organisms called microbes. Some of these organisms are harmless while others are able to cause infection and damage. Thus, our body has defense mechanisms that include the immune system. Macrophages are cells that belong to the immune system and have key roles in defense against infection, wound healing, and r

Klimatförändringar förväntas leda till längre brandperioder och ökad brandrisk. I Sverige, där homogen produktionsskog utgör största delen av landskapet, finns ett behov av bättre förståelse för skogens mottaglighet för bränder för att kunna mildra risker. I denna avhandling avser skogsbrandmottaglighet sannolikheten för att skogen brinner efter att antändning har ägt rum och inledande brandspridnClimate change is expected to result in longer fire seasons and increased fire risk. In Sweden, where homogenous production forest makes up the majority of the landscape, there is a need for better understanding of forest fire susceptibility in order to mitigate risk. In the context of this thesis forest fire susceptibility is the likelihood of forest burning after ignition and initial fire propag

Trots att det idag är krav på vägledande markeringar finns det i dagsläget lite kunskap om i vilken utsträckning de faktiskt gör nytta. Det är därför av intresse att studera om människor verkligen tittar på dessa i en utrymningssituation. Denna studie undersöker huruvida människor observerar vägledande markeringar där tre olika skylttyper testats för att se om det finns skillnader. De tre skylttyThe use of exit signage is legally regulated even thought there is a lack of knowledge regarding the extent to which they help. It’s therefore of interest to study if people actually look at them in an evacuation situation. This thesis examines whether people observe exit signage, whereas three different sign types are tested to conclude differences. The three tested types were normal, illuminate

Syftet med uppsatsen är att undersöka hur familjevåld påverkar bedömningen av barnets bästa i frågor om vårdnad, boende och umgänge. Med våld avses våld riktat mot någon annan i familjen än barnet. Jag har använt mig av tre frågeställningar för att lyfta fram vilken betydelse våldet har för barnet. Den första frågeställningen är mer övergripande och handlar om hur våldet påverkar barnets bästa. DeThe aim of this thesis is to examine how domestic violence affects the decision of what is in the best interest of the child with regards to parental authority judgments. In this thesis the term domestic violence refers to all violence towards another family member except the child himself. The thesis is built upon three questions in order to highlight the impact domestic violence has upon the dec