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Background: Many persons with late effects of polio (LEoP) perceive walking limitations in everyday life. A common rating scale to assess walking limitations is the Walking Impact Scale (Walk-12). However, there is limited knowledge about its psychometric properties. Objective: To investigate the psychometric properties of Walk-12 in persons with LEoP. Design: Rasch model analysis of cross-section

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BACKGROUND & AIMS: Corticosteroids alone or in conjunction with azathioprine (AZA) is the standard treatment in autoimmune hepatitis (AiH). Individual variations in thiopurine (TP) metabolism may affect both drug efficacy and toxicity. Our aim was to investigate the utility of thiopurine methyltransferase (TPMT) as well as thioguanine nucleotide (TGN) and methylthioinosine monophosphate (meTIM

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BACKGROUND: Patients with elevated intracranial pressure risk compromising their cerebral blood flow, resulting in ischemia. Lowering of the raised intracranial pressure, is therefore, mandatory. Reduction of the cerebral blood volume (CBV) might be target. In finding ways to do so, one has to be able to measure CBV. Measurement of CBV is, however, difficult. Radio(99mTc-)labeled erythrocytes (99m

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Popular Abstract in English The aim of this thesis is to investigate the evolution of new technology-based firms (NTBFs) based on solid empirical material for the Swedish economy. The focus on this thesis is exploring the role of acquisition by incumbent firms in the evolution of NTBFs. The findings of this thesis show that selection is a core feature in the evolution of NTBFs. NTBFs experience a The aim of this thesis is to explore the evolution of new technology-based firms (NTBFs) based on solid empirical material for the Swedish economy. NTBFs are argued to be one important type of entrepreneurial firms that contribute to technology change, knowledge spillovers, and economic growth. However, our knowledge concerning how NTBFs exert their technological and economic influences is far fro

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Electricity must be produced at the same time as it is used. This necessitates flexibility in the electricity production and electricity networks. Until recently, the increase in electricity demand and peak power demand has been met by expansion of the electricity production. Today, due to the deregulation of the electricity market, the production capacity is decreasing. Therefore, there is a nati

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BACKGROUND: Physical activity (PA) is part of a healthy lifestyle and prevents many chronic health problems, in addition to promoting mental health. PA performed outdoors has been found particularly good for promoting one's well-being. The aim of this study was to investigate the extent to which outdoor recreational PA was carried out during 1 year, and the factors influencing such activities from

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Turbulent premixed flames subjected to extreme levels of turbulence exhibit reaction zone broadening and thinning. Instantaneous flame structures visualized using advanced laser diagnostic methods have shown significantly different behaviours of flame/turbulence interaction in jet flames stabilized on burners of different sizes. This paper aims to reconcile the controversy about flame broadening o

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As both a utility mode of transport and recreational activity, cycling has well-known health, environmental, and economic benefits. For these reasons it has been encouraged in many countries, including the Republic of Ireland. However, with increasing popularity there have been concurrent increases in road traffic related cyclist injuries. This study aims to characterise cyclist collisions, which

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AIMS: This study aimed to evaluate the association between physical activity and the incidence of coronary heart disease (CHD) in individuals with and without CHD risk factors. METHODS AND RESULTS: EPIC-CVD is a case-cohort study of 29 333 participants that included 13 582 incident CHD cases and a randomly selected sub-cohort nested within the European Prospective Investigation into Cancer and Nut

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Background: Rectal washout (RW) is routinely performed during anterior resection (AR) for rectal cancer to reduce local recurrence (LR), although is sometimes not performed during minimally invasive surgery (MIS) procedures due to technical challenges and time consumption. The aim was to investigate the impact of RW on the oncological outcome after AR for rectal cancer in a registry cohort. Method

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This article is about psychiatric patients’ life stories. I explore how best to handle patient narratives in the history of medicine and, more specifically, in the history of psychiatry. By applying a narrative and phenomenological analysis – seldom used in historical studies of psychiatry and psychiatric care – the aim is a new understanding of patient stories both as historically situated and as

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The unprecedented x-ray flux density provided by modern x-ray sources offers new spatiotemporal possibilities for x-ray imaging of fast dynamic processes. Approaches to exploit such possibilities often result in either (i) a limited number of projections or spatial information due to limited scanning speed, as in time-resolved tomography, or (ii) a limited number of time points, as in stroboscopic

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Denna avhandling undersöker hur subtila former av medborgerligt motstånd tar form i Hongkongs pågående autokratisering. I en kontext präglad av vilande sociala rörelser, ökande mediecensur och digital övervakning visar studien att uttryck som inte aktivt söker uppmärksamhet ändå kan spela en viktig roll i medborgerligt engagemang. Med utgångspunkt i Hongkong efter införandet av den nationella säkThis thesis challenges the assumption that expressions that do not actively seek attention is less significant in the research of civic engagement, by foregrounding the arts of subtle resistance in contexts of social movement abeyance, heightened media censorship and digital surveillance. Drawing upon the empirical case of Hong Kong, where a National Security Law was enacted in 2020 to discourage

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Moult, the regular replacement of feathers, is a resource-intense avian annual-cycle stage. Resource allocation to support feather regrowth may require downregulation of other physiological processes, such as immune function, which is critical for preventing disease-related mortality. At the same time, the emergence of new feathers may increase the risk of skin injury and infection, potentially re

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ContextUp to half of patients with adrenal adenomas found as incidentalomas show biochemical signs of subtle cortisol hypersecretion without having clinical signs or symptoms of Cushing’s syndrome. A condition called autonomous cortisol secretion (ACS). Previous studies have indicated that ACS might be associated with increased mortality.ObjectivesExplore if ACS is an independent risk factor for i

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INTRODUCTION: Neurological complications after surgery for acute type A aortic dissection (ATAAD) increase patient morbidity and mortality. Carbon dioxide flooding is commonly used in open-heart surgery to reduce the risk of air embolism and neurological impairment, but it has not been evaluated in the setting of ATAAD surgery. This report describes the objectives and design of the CARTA trial, in

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Background: Welders are exposed to gas and particle emissions that can cause severe lung disease, such as chronic obstructive pulmonary disease (COPD), a leading cause of mortality and morbidity worldwide. It is difficult to detect COPD early and therefore mitigating measures may be delayed. The aim of this study was to investigate lung health in welders and evaluate new sensitive methods with pot

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Extreme environmental conditions make soils of the hyper-arid Atacama Desert one of the most hostile habitats for life on the planet. During the short intervals of moisture availability that occur, it remains unresolved how soil microorganisms physiologically respond to such dramatic environmental changes. Therefore, we simulated a precipitation event – without (H2O) and with (H2O + C) labile carb