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Hemorrhagic transformation (HT) is a complication of severe ischemic stroke after revascularization. Patients with low platelet counts do not receive reperfusion therapies due to high risk of HT. The immunomodulatory drug fingolimod attenuated HT after tissue plasminogen activator in a thromboembolic stroke model, but the underlying mechanism is unknown. Fingolimod acts on several sphingosine-1-ph
This thesis is an exploration of leadership dimensions of academic organisational processes. It consists of four case studies, each presenting a leadership challenge. These studies of specific situations offer great opportunities to investigate the variety of leading that the academy contains. There is focus, not so much on the task but on the process in which the challenges are positioned, how th
IntroductionConsidering that on average in developed countries we spend about 65% of our time in private homes, understanding the exposures in homes is of outmost importance. Aerosol concentrations indoors come from indoor sources, infiltrate from outdoors and can be formed from precursors both of indoor and outdoor origin. Several characteristics and processes influence the properties of aerosols
Abstract: The concentrations of cyclic AMP, noradrenaline, glycogen, glucose, lactate, pyruvate, labile phosphate compounds, and free fatty acids were investigated in the rat neocortex and hippocampus during and following cerebral ischemia. An incomplete ischemia of 5 and 15 min duration was induced by bilateral carotid clamping combined with hypotension. The postischemic events were studied afte
OBJECTIVES: One of the theories connecting enterovirus (EV) infection of human islets with type 1 diabetes (T1D) is the development of a fertile field in the islets. This implies induction of appropriate proteins for the viral replication such as the coxsackie-adenovirus receptor (CAR). The aim of this study was to investigate to what extent CAR is expressed in human islets of Langerhans, and what
Context. The dynamics of a low-mass protoplanet accreting solids is influenced by the heating torque, which was found to suppress inward migration in protoplanetary disks with constant opacities. Aims. We investigate the differences in the heating torque between disks with constant and temperature-dependent opacities. Methods. Interactions of a super-Earth-sized protoplanet with the gas disk are e
Sda is a high-frequency carbohydrate histo-blood group antigen, GalNAcβ1-4(NeuAcα2-3)Galβ, implicated in pathogen invasion, cancer, xenotransplantation and transfusion medicine. Complete lack of this glycan epitope results in the Sd(a−) phenotype observed in 4% of individuals who may produce anti-Sda. A candidate gene (B4GALNT2), encoding a Sda-synthesizing β-1,4-N-acetylgalactosaminyltransferase
1. Carbon monoxide (CO), produced by haem oxygenase through degradation of haem, has been claimed to be a neuromessenger and a possible regulator of vascular tone. We examined whether the haem oxygenase inhibitor, zinc protoporphyrin-IX (ZnPP) and other porphyrins affect the relaxation evoked by various agents in the rat isolated aorta. 2. Pretreatment with ZnPP (0.1 mM) virtually abolished the re
We performed spatially resolved near-ambient-pressure photoemission spectromicroscopy on graphene-coated copper in operando under oxidation conditions in an oxygen atmosphere (0.1 mbar). We investigated regions with bare copper and areas covered with mono- and bi-layer graphene flakes, in isobaric and isothermal experiments. The key method in this work is the combination of spatial and chemical re
The aim of this paper was to explore the perceptions and images of mental illness that is conveyed in the media form of internet magazines, more precisely in the discussion forums that are found below the articles. This paper also explored how the category of people with mental health problems related to these structures. A central focus was to investigate how the image was constructed from the ta
The current study set out to investigate patterns of loanwords in a sample of 1,460 lexical meanings in the Finnish lexicon by means of quantitative methods. The methodology used was borrowed from the Loanword Typology project (Haspelmath & Tadmor 2009a), and consisted of a template including various fields, where information about each lexical item was coded. The fields included measures such
Denna framställning berör kränkningar som riktar sig mot den personliga integriteten och som framförs via internet. Nätbaserade kränkningar är ett problem vilket drabbar många enskilda som deltar i debatter eller har delar av sina sociala liv på internet. Olika grupper utsätts för olika typer av kränkningar och vissa grupper är mer utsatta än andra. Det är viktigt att lagstiftningen håller sig upp
Skönhetsingrepp kan leda till skador eller missnöje med det estetiska resultatet. Det har länge funnits kritik mot att skönhetsbranschen saknar ett anpassat och tydligt regelverk. Syftet med uppsatsen är därmed att utifrån en rättsanalytisk metod undersöka och problematisera möjligheten till ansvarsutkrävande vid felaktiga skönhetsingrepp som har genomförts i Sverige. Min första frågeställning b
This study is based on the reflections that society's activities have a negative impact on the climate and that there are planetary boundaries that need to be taken into account if ecological sustainability will have a chance to be achieved. Today the Swedish housing sector is quite resource intensive and contribute to about 20 percent of the Swedish emissions of carbon dioxide, which is about
Abstract Author: Chanette Edman Title: Blinded love - a description of how the violence in a relationship is normalized by the victim and what leads to the breakup of the relationship Supervisor: Anna Rypi Assessor: Summary: This is a qualitative text analysis about how women who live in violent relationships describe their experiences in autobiographies. The aim of the study was to find out
Användningen av korslimmat trä (KL-trä) befinner sig i en expanderande fas. Tillämpn-ingen av KL-trä som byggnadsmaterial är relativt nytt och övergripande dimensioneringsstandarder har ännu inte utvecklats fullt ut. Ett fall där inga allmänna dimensioneringsstandarder existerar är fallet plattelement av KL-trä med hål. En dimensioneringsmetod som utgår ifrån en balkrostmodell har föreslagits för The use of cross laminated timber (CLT) is expanding, its use is relatively new and universal design standards are lacking. One situation for which no universal design standard exists is that of a CLT plate element with an opening. A grillage method has been proposed as a convenient method to design such plate elements. The grillage method consists of analyzing a beam grillage model in terms of be
Geothermal energy is one of the oldest and most sustainable energy sources and has been used for thousands of years. The temperature of the ground at shallow depth is fairly constant, above the air temperature in winter and lower than the ambient temperature in summer. Shallow geothermal energy systems can thus be used to provide heating and cooling with or without heat pumps. This study aims to
Den aktuella studiens syfte var att undersöka om det finns ett samband mellan upptagenhet av kost och träning och fyra psykologiska faktorer: hälsoångest, självkänsla, känsla av sammanhang och kroppsuppfattning, då psykiskt välmående som begrepp är alltför mångfacetterat. Ett ytterligare syfte var att undersöka om upptagenhet av kost och träning skiljde sig åt beroende på specifika egenskaper hos The purpose of the present study was to examine whether there are connections between preoccupation with diet, and exercise, and four psychological factors: health anxiety, self-esteem, sense of coherence, and body image, since psychological well- being is a broadly used term. Another aim was to examine whether the preoccupation with diet, and exercise differed depending on some specific character
