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Purpose: Manufacturer specifications for the resolution of an additive manufacturing (AM) machine can be ten times smaller (more optimistic) than the actual size of manufacturable features. Existing methods used to establish a manufacturable design rule-set are conservative piecewise-constant approximations. This paper aims to evaluate the effectiveness of a first-order model for producing improve
Functional gastrointestinal disorders constitute a set of gastrointestinal disorders with absence of obvious organic and physiological dysfunctions observed in clinical routine examinations. The functional disorders are divided into many subclasses, e.g., functional esophageal disorders and functional bowel disorders. The diagnoses are set when the patients fulfil the Rome IV criteria after a care
Obesity is one of the principal human health problems and one of the main treatments against it is the inhibition of pancreatic lipase, the main responsible enzyme of lipid digestion. For that purpose, previous studies have tested several phenolic compounds against lipase, without considering their aggregation behavior in aqueous solutions. Because of this, the present study focuses on understandi
Benthic macroinvertebrates are part of a complex network of interactions. The spatial and temporal scales of the processes that form the basis for these interactions have traditionally restricted their empirical investigation. The first chapter of the manuscript attempts a review of the modelling tools that have been employed for the study of the marine benthos.The implementation of a mechanistic
This book analyses the way in which international human rights law (IHRL) and international investment law (IIL) are deployed – or fail to be deployed – in conflict countries within the context of natural resources extraction. It specifically analyses the way in which IIL protections impact on the parallel protection of economic, social and cultural rights (ESC rights) in the host state, especiall
The meteoritic material falling on Earth is believed to derive from large break-up or cratering events in the asteroid belt. The flux of extraterrestrial material would then vary in accordance with the timing of such asteroid family-forming events. In order to validate this, we investigated marine sediments representing 15 time-windows in the Phanerozoic for content of micrometeoritic relict chrom
Atherosclerosis is a major underlying cause of cardiovascular disease. Previous studies showed that inhibition of the co-stimulatory CD40 ligand (CD40L)-CD40 signaling axis profoundly attenuates atherosclerosis. As CD40L exerts multiple functions depending on the cell-cell interactions involved, we sought to investigate the function of the most relevant CD40L-expressing cell types in atheroscleros
Distribution of responsibility is one of the main focus areas in discussions about climate change ethics. Most of these discussions deal with the distribution of responsibility for climate change mitigation at the international level. The aim of this paper is to investigate if and how these principles can be used to inform the search for a fair distribution of responsibility for climate change ada
We investigated injury-induced heat shock protein 27 (HSP27) expression and its association to axonal outgrowth after injury and different nerve repair models in healthy Wistar and diabetic Goto-Kakizaki rats. By immunohistochemistry, expression of HSP27 in sciatic nerves and DRG and axonal outgrowth (neurofilaments) in sciatic nerves were analyzed after no, immediate, and delayed (7-day delay) ne
This practice-based PhD project investigates the conditions for a pedagogy of the utopian image in contemporary art and film. It starts from the premise that there is a need for new political and social visions and scenarios. The project asks what role art and artist film, both as a medium and as a social activity, can play in experimenting with and sketching such visions and scenarios – a process
Biochemical signaling is mediated by complexes between macromolecular receptors and their ligands, with the duration of the signal being directly related to the lifetime of the ligand-receptor complex. In the field of drug design, the recognition that drug efficacy in vivo depends on the lifetime of the drug-protein complex has spawned the concept of designing drugs with particular binding kinetic
It is well-known that adsorption of proteins on interfaces often induces substantial alterations of the protein structure. However, very little is known about whether these conformational changes have any consequence for the protein conformation after desorption from the interface. To investigate this matter, we have selected a protein−particle system in which the enzyme human carbonic anhydrase I
Research on social capital has highlighted its significance for labor market integration, particularly regarding informal job search strategies. However, how do second-generation immigrants perceive and make use of social capital and its resources in Sweden's labor market? This thesis examines the relationship between the quality of social capital, measured by the occupational status of respon
This thesis critically examines how corporate stakeholders frame the social impacts of the Lake Turkana Wind Power Project (LTWP) in Kenya. By scrutinising how social impacts are framed, this thesis sets out to analyse how discursive strategies can shape justice outcomes of renewable energy projects. By doing so, contribute to the current academic discourse on energy justice of renewable energy pr
Wind-assisted ship propulsion has gained increasing attention as a means of reducing fuel consumption and emissions in the maritime sector. This thesis studies the aerodynamic performance of an adjustable rigid wingsail designed to provide auxiliary thrust for ships. The wingsail consists of a NACA 0018-based main airfoil with a movable flap, where the flap deflection, hinge position, and gap betw
In Sweden every property unit needs to go through a suitability judgement when subdivided or amended. The judgement asks whether the property unit is suitable for its intended use regarding how the property unit´s boundary is drawn. What constitutes a suitable property unit is well established for most types of uses. This is not the case for property units with a dam on them, so called dam-propert
This paper examines how the EU seeks to mitigate external economic vulnerabilities and what this reveals about the EU’s prioritisation concerning different types of vulnerability and the external actors toward whom these vulnerabilities are directed. The paper draws on the theories of complex interdependence and weaponised interdependence to distinguish between resource-based and network-based vul
This project investigates how power operates as performative in the everyday work experiences of employees of different ethnic backgrounds in a multinational organization. Rather than treating power as a stable possession held by individuals or institutions, the study conceptualizes power as enacted, reproduced, and negotiated through routine individual and organizational practices. For migrants t
Cuban Medical Internationalism constitutes a prime example of healthcare cooperation within South-South Cooperation. While having a lengthy historical tradition driven by solidarity, it was subjected to human rights concerns regarding its physicians employed abroad. As these experiences are embedded in broader structures of inequality, they resemble the concept of structural violence. The study, t
