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Heavy Metal Exposure in Early Life - Health and Labour Market Perspectives

This thesis consists of three empirical studies on the effects of exposure to heavy metal pollution in early childhood on a broad set of individual outcomes. The first study analyses how accumulated exposure to metal pollution during childhood affects long-run outcomes. Exploiting policy-driven reductions in metal pollution in Sweden, it shows that accumulated exposure to metals (including cadmium

Some Physical and Environmental Aspects of Shallow Ice Covered Lakes : Emphasis on Lake Vendyurskoe, Karelia, Russia.

The ice cover presence on the surface of a lake insulates the water body from the atmosphere. This prevents or reduces the influence of processes which depend on the exchange between the atmosphere and the water surface. This implies significant reduction or elimination of some processes taking place at the open water surface; for instance, a substantial reduction in solar energy penetrating to th

Facilitators and barriers associated with the implementation of a Swedish psychosocial dementia care programme in Japan : a secondary analysis of qualitative and quantitative data

Background: A psychosocial dementia care programme for challenging behaviour (DEMBASE®) was developed in collaboration with a Swedish BPSD-registry team for in-home care services use in Japan. The programme consisted of a web-based tool for the continued assessment of challenging behaviours and interdisciplinary discussion meetings. Effectiveness of the adapted programme was verified through a clu

Stakeholder-based Brand Equity (SBBE) : A qualitative study of its development through firm-stakeholder interactions in emerging markets

This thesis challenges the prevailing firm-consumer/customer-centric and dyadic perspective that prevails within the brand equity literature, which is based on a linear, straightforward stimulus-response approach to the creation of brand value. Leaning on the literature on interorganisational relationships, stakeholder theory, market emergence/market driving, and firm internationalisation, which s

Study protocol : Differential effects of diet and physical activity based interventions in pregnancy on maternal and fetal outcomes: Individual patient data (IPD) meta-analysis and health economic evaluation

BackgroundPregnant women who gain excess weight are at risk of complications during pregnancy and in the long term. Interventions based on diet and physical activity minimise gestational weight gain with varied effect on clinical outcomes. The effect of interventions on varied groups of women based on body mass index, age, ethnicity, socioeconomic status, parity, and underlying medical conditions

Physical barriers and environmental gradients cause spatial and temporal genetic differentiation of an extensive algal bloom

Aim: To test if a phytoplankton bloom is panmictic, or whether geographical and environmental factors cause spatial and temporal genetic structure. Location: Baltic Sea. Method: During four cruises, we isolated clonal strains of the diatom Skeletonema marinoi from 9 to 10 stations along a 1132 km transect and analysed the genetic structure using eight microsatellites. Using F-statistics and Bayesi

Multiple stressors in rotifer communities: : Effects of predation, climate change, and brownification

De flesta vattenlevande organismer på Jorden lever i en miljö där de samtidigt måste hantera flera olika hot och stressituationer, såsom t.ex. predation, klimatförändringar och brunifiering. Trots relativt god kunskap om varje stressfaktor för sig, vet man förvånansvärt lite om hur synergier av samtidigt förekommande hot påverkar organismer. Därför har jag i min avhandling undersökt hur predation,Most organisms on Earth live in an environment where they are exposed to multiple pressures, including predation and climate change. In many aquatic ecosystems, organisms have to handle additional challenges such as brownification, co-occurring with climate warming. Despite the growing recognition of impacts of climate warming or brownification on the freshwater communities, little is known on how

Pyk2 inhibition promotes contractile differentiation in arterial smooth muscle

Modulation from contractile to synthetic phenotype of vascular smooth muscle cells is a central process in disorders involving compromised integrity of the vascular wall. Phenotype modulation has been shown to include transition from voltage-dependent toward voltage-independent regulation of the intracellular calcium level, and inhibition of non-voltage dependent calcium influx contributes to main

Loneliness, health and mortality

Aims.: Literature suggests an association between loneliness and mortality for both males and females. Yet, the linkage of loneliness to mortality is not thoroughly examined, and need to be replicated with a long follow-up time. This study assessed the association between loneliness and mortality, including associations to gender, in 1363 adult swedes. Methods.: This community-based prospective co

Ecological factors influence timing of departures in nocturnally migrating songbirds at Falsterbo, Sweden

Most songbirds depart from stopover sites after sunset and migrate during the night. Several recent studies have reported larger variation in departure time than previously thought; yet, it is still unclear which factors govern departure timing. We investigated the departure timing of four species of nocturnally migrating songbirds using an automated radiotelemetry system at Falsterbo peninsula in

Evaluation of Different Turbocharger Configurations for a Heavy-Duty Partially Premixed Combustion Engine

The engine concept partially premixed combustion (PPC) has proved higher gross indicated efficiency compared to conventional diesel combustion engines. The relatively simple implementation of the concept is an advantage, however, high gas exchange losses has made its use challenging in multi-cylinder heavy duty engines. With high rates of exhaust gas recirculation (EGR) to dilute the charge and he

Identification of Subtypes in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Reveals a Gene Signature Prognostic of Outcome.

PURPOSE: Human epidermal growth factor receptor 2 (HER2) gene amplification or protein overexpression (HER2 positivity) defines a clinically challenging subgroup of patients with breast cancer (BC) with variable prognosis and response to therapy. We aimed to investigate the heterogeneous biologic appearance and clinical behavior of HER2-positive tumors using molecular profiling. PATIENTS AND METHO

Alcohol intoxication at 0.06 and 0.10% blood alcohol concentration changes segmental body movement coordination.

Alcohol intoxication is the cause of many falls requiring emergency care. The control of upright standing balance is complex and comprises contributions from several partly independent mechanisms like coordination, feedback and feedforward control and adaptation. Analysis of the segmental body movement coordination offers one option to detect the severity of balance problems. The study aims were (

Health status and functional profile at admission of nursing home residents in Iceland over 11-year period.

Health status and functional profile at admission of nursing home residents in Iceland over 11-year period. International Journal of Older People Nursing doi: 10.1111/j.1748-3743.2011.00287.x Background. The knowledge over time of the health status and changes in care needs of newly admitted nursing home residents is limited. Objectives. To investigate trends in residents' health status and functi

Annoyance and performance of three environmentally intolerant groups during experimental challenge with chemical odors.

OBJECTIVES: This study investigated exposure- and subject-related determinants of annoyance and performance during the chemical odor provocation of healthy persons with self-reported environmental annoyance. METHODS: Persons with self-reported annoyance attributed to (i) chemicals or smells (smell-annoyed, SA, N=29), (ii) electrical equipment (electrically annoyed, EA, N= 16), and (iii) both smell

Skyddsåtgärder för att förhindra dödligt våld mot kvinnor i nära relationer - En kritisk studie av straffrättsliga åtgärder vid brottet "grov kvinnofridskränkning"

Varje år dör omkring tretton kvinnor i Sverige till följd av våld av en man som de har eller har haft en nära relation med. Ofta kulminerar våldet vid en separation eller skilsmässa. Det kan därför innebära en högre risk för dödligt våld under separationsfasen. Den drivande kraften bakom våldet är vanligtvis svartsjuka och kontroll från mannen, vilket han känner en förlust av vid tillfället då kviEvery year about thirteen women die in Sweden because of the violence of a man they have or have had a close relationship with. Often the violence culminates in a separation or divorce. Therefore, it may involve a higher risk of fatal violence during the separation phase. The driving force behind the violence is usually jealous and control from the man, which he knows a loss at the moment when the

Ersättningsansvar avseende förarlös fordonskörning

Tanken på självkörande bilar har funnits nästan lika länge som det har funnits bilar. Denna uppsats har ämnat utreda vilka rättsekonomiska konsekvenser en skada vållad av ett förarlöst fordon medför samt hur lagstiftningen ur ett de lege ferenda-perspektiv bör vara utformat utifrån rättsekonomiska teorier. Rättsekonomi sträva efter ekonomisk effektivitet. Detta skapar välstånd för individer och vä

Lite isolering har väl ingen dött av – En komparativ studie av Häktes- och restriktionsutredningens lagförslag (SOU2016:52) i relation till den norska lagstiftningen

Sverige har i över tjugo års tid, från såväl nationellt som internationellt håll, utstått omfattande kritik angående långa häktestider och en allt för liberal restriktionsanvändning. Vissa mindre förändringar har skett med tiden men de svenska problemen kvarstår i stort oförändrande än idag. I ett försök att åtgärda problemen tillsatte regeringen en utredning som presenterade sitt betänkande 2016,Sweden has during the last 20 years received severe criticism, both national and international, on the widespread use of remand imprisonment and a too liberal practice in its use of restriction. Some minor changes have been made to the legislation on the matter but the criticism remains in its major part unchanged. During 2015, the government made an effort to overcome this issue by appointing a p

När anses någon ha deltagit frivilligt? - En analys av våldtäktsbestämmelsens tolkning i rättstillämpningen.

Införandet av en så kallad samtyckeslag har varit kraftigt omdebatterat i över två decenniers tid. Den 1 juli 2018 infördes en våldtäktsbestämmelse som baseras på frivillighet. I och med detta utvidgades våldtäktsbestämmelsen på så sätt att det inte längre fordras tvång eller utnyttjande av en särskilt utsatt situation för att straffansvar ska aktualiseras. Syftet med den nya våldtäktsbe-stämmelseThe adoption of a so-called consent-based rape law has been heavily debated for over two decades. On July 1st, 2018 a rape clause based on voluntarism was introduced. As a result, the rape regulation was extended in such a way that it no longer requires force, or exploitation of a particular vulnerable situa-tion, for criminal liability to occur. The purpose of the new rape regulation is to protec