Sökresultat

BACKGROUND: Differential gene expression in adipose tissue during diet-induced weight loss followed by a weight stability period is poorly characterized. Markers of these processes may provide a deeper understanding of underlying mechanisms. OBJECTIVE: We aimed to identify differentially expressed genes in human adipose tissue during weight loss and weight maintenance after weight loss. DESIGN:

The treatment of prostatic carcinoma with estrogens is associated with an increased risk of cardiovascular as well as thromboembolic complications. In the present study, patients harboring highly or moderately differentiated prostatic carcinoma without signs of metastases were treated with either polyestradiolphosphate + etinylestradiol, estramustine phosphate or given no treatment. Subsequently,

Scand J Caring Sci; 2011 Individual placement and support - a model to get employed for people with mental illness - the first Swedish report of outcomes Lack of participation in the open labour market is highly prevalent for people with a mental illness across countries, and the proportion of people who get some kind of sickness benefit because of mental illness is steadily growing in Europe. Voc

Galiellalactone is a potent and specific inhibitor of STAT3 signaling which has been shown to possess growth inhibitory effects on prostate cancer cells expressing active STAT3. In this study we aimed to investigate the effect of galiellalactone on prostate cancer stem cell-like cells. We explored the expression of aldehyde dehydrogenase (ALDH) as a marker for cancer stem cell-like cells in differ

Trees growing at their altitudinal or latitudinal distribution in Fennoscandia have been widelyused to reconstruct warm season temperatures, and the region hosts some of the world’slongest tree-ring chronologies. These multi-millennial long chronologies have mainly beenbuilt from tree remains found in lakes (subfossil wood from lake-shore trees). We used aunique dataset of Scots pine tree-ring dat

The aim of this study was to investigate if costimulation blockade could be used to modulate the immune response, to prevent rejection, and to stimulate regeneration into nerve allografts. Nerve allografts from Balb/C mice, and isogenic nerve grafts (isografts) from C57/BL6 mice, were used to bridge a 7-mm gap of the sciatic nerve in C57/BL6 mice. Allograft recipients were treated with either a tr

A cross-sectional study was conducted to assess the extent of unstructured HIV treatment interruptions (TIs) and investigate the effects of socioeconomic, socio-demographic, HIV treatment-related and clinical factors on the magnitude and rate of the same among adult patients at a Kenyan regional referral center. Four hundred and twenty-one adult patients actively receiving antiretroviral therapy a

INTRODUCTION: Hyperactivity of the hypothalamic-pituitary-adrenal (HPA)-axis is a common finding in major depressive disorder. Similar studies on suicide attempters are less abundant, and the results are divergent. The main aim of the present study was to investigate HPA-axis parameters by the time of a suicide attempt and at follow-up in search for associations between HPA-axis function and suici

BACKGROUND:: Epidemiological reports on risk and prognostic factors in patients with mesenteric venous thrombosis (MVT) are scarce. METHODS:: Patients with MVT were identified through the inpatient and autopsy registry between 2000 and 2006 at Malmö University Hospital. RESULTS:: Fifty-one patients had MVT, diagnosed at autopsy in six. The highest incidence (11.3 per 100 000 person-years) was in t

Single-nucleotide polymorphisms (SNPs) in the major histocompatibility complex class II transactivator (MHC2TA) gene encoding the class II transactivator have been associated with multiple sclerosis, rheumatoid arthritis, and myocardial infarction in the Swedish population. We used a case-control approach to investigate the prevalence of a relevant variant in Swedish systemic lupus erythematosus (

Hypothermia is shown to be beneficial for the outcome after a transient global brain ischaemia through its neuroprotective effect. Whether this is also the case after focal ischaemia, such as following a severe traumatic brain injury (TBI), has been investigated in numerous studies, some of which have shown a tendency towards an improved outcome, whereas others have not been able to demonstrate an

The meaning of the word cavitation is not known or understandable for many people. The definition which is commonly known about such phenomena is that the formation of cavities or bubbles is encouraged by a pressure change in the surroundings. However, cavitation is much more complex. A large amount of research work and studies on the dynamics of the cavitation phenomenon via numerical investigati

Micropollutants, such as pharmaceutical residues, are increasingly prevalent in water sources, posing significant risks to human and animal health while contributing to antimicrobial resistance. Despite high-standard wastewater treatment across the EU, the effective removal of micropollutants requires the adoption of more advanced treatment technologies, specifically quaternary treatment technolog

In this qualitative and poststructuralist policy analysis, the Swedish Crime policy is examined as it is expressed through three political documents from three different parties during the post-election period of October 2022-March 2024. Using Laclau and Mouffe’s discourse theory, with its Lacanian influence on the subject, this paper investigates the political language used in the policy area dur

Det här arbetet undersöker användningen av realtidsgenererade miljöer i virtuell verklighet (VR) som ett sätt att förbättra förståelse och bibehållandet av kunskap hos användare. Genom en iterativ designprocess integrerades en tal-till-text-modell i VR tillsammans med en algoritm för att hämta ut nyckelord. Systemet testades först i pilotstudier som prototyper, förbättrades genom feedback och anväThis thesis investigates the use of real-time environment generation in virtual reality (VR) as a way to enhance learner comprehension and knowledge retention. Using an iterative design process, a speech-to-text (STT) model was integrated into VR with a keyword-extraction algorithm, first as a prototype in pilot tests, refined with feedback then finally used in a user study. The study compared thr

Cloudbursts and flooding that results from such intense rainfall constitute a growing risk as climate change intensifies precipitation patterns. This is a growing issue that municipalities can no longer ignore; they must actively address it. The issue of cloudbursts is highly relevant given the future climate risks we face, and it is important that Swedish cities are prepared. In this context, the

Organisational ideology is present to certain degrees in every workplace. Yet the research field around employee alignment on organisational ideologies is sparse and underdeveloped. Harnessing the power of an organisational ideology – particularly where that ideology leaves room for individual employees to express their spiritual identity in the workplace – has been found to bring many benefits. T

This thesis has investigated the potential of combining Raman spectroscopy with Sheimpflug Light Detection and Ranging (lidar) for simultaneous characterization and ranging of aerosolized soot. The first part of the project involved the implementation of conventional non-ranging Raman spectroscopy for both deposited and aerosolized soot. The second part constituted the design, modelling, and evalu