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The objectives of the thesis were to seek a better understanding of polymorphic RBC surface molecules in the Thai, and to investigate the role of certain blood groups in malarial invasion. MALDI-TOF MS was employed in Study I as an efficient method for genotyping to establish the common blood group and platelet antigen genotypes of 396 blood donors. Investigation of outliers identified variation a
Dopamine replacement therapy for Parkinson's disease is achieved using L-DOPA or dopamine D2/3 agonists, such as ropinirole. Here, we compare the effects of L-DOPA and ropinirole, alone or in combination, on patterns of glial and microvascular reactivity in the striatum. Rats with unilateral 6-hydroxydopamine lesions were treated with therapeutic-like doses of L-DOPA (6 mg/kg), an equipotent L-DOP
What will the low-carbon cities of tomorrow be made from? We see an unexpected answer today in the return of ‘premodern’/‘preindustrial’ materials to central cities and skylines. Champions of new mass timber materials have driven a race on iconic ‘plyscrapers’ and, increasingly, novel systems of industrial prefabrication. Drawing on the notion of sociotechnical imaginaries, we explore how advocate
The translational mobility of aggregates formed in aqueous sodium cholate solutions was obtained from the self-diffusion coefficient of solubilized decanol, which was determined using the capillary tube method with radioactive labeling. Combining these results with the self-diffusion coefficients of cholate ions, sodium ions, and water molecules the following quantities were determined as a functi
We report the first incorporation of S-nitroso-N-acetylpenicillamine (SNAP) into micellar systems of the poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) triblock copolymer Pluronic® F127 for nitric oxide (NO) delivery and show how sodium taurodeoxycholate (NaTDC) modulates F127 micellization and gelation. Using differential scanning calorimetry, small-angle X-ray scat
Background: Bone and mineral disorders are common in patients with chronic kidney disease (CKD), leading to poor quality of life, high fracture risk, and increased morbidity and cardiovascular mortality. Parathyroid hormone (PTH) and bone-specific alkaline phosphatase (bALP) are frequently used to assess bone turnover, but markers such as procollagen type I N-terminal propeptide (intact PINP) and
Uppsatsen undersöker hur självförvållat rus har beaktats i svensk straffrätts ansvarsbedömning över tid. Analysen fokuserar på hur förhållandet mellan gärningsmannens faktiska sinnestillstånd, uppsåtskravet och möjligheten att utkräva straffansvar har förändrats. Framställningen tar sin utgångspunkt i den svenska stormaktstiden och följer utvecklingen fram till dagens reglering i 1 kap. 2 § 2 st. This thesis examines how self-induced intoxication has been taken into account in Swedish criminal law's assessment of criminal responsibility and intent over time. The analysis focuses on how the relationship between the perpetrator's actual state of mind, the requirement of intent, and the possibility of imposing criminal liability has changed. The presentation takes its starting point i
Valence is a fundamental yet ambiguously defined concept in chemistry, playing a central role in the description of molecular structure, bonding, and reactivity. This thesis examines the quantum mechanical Veryazov valence formula (referred to as the original formula), which determines atomic valence based on density matrix analysis. The aim of this work is to assess the robustness of this valence
En av de vanligaste frågorna som brukar ställas till astronomer är om det finns liv någon annanstans i universum. Vi har ännu inget enkelt svar. Framsteg mot ett svar på denna fråga görs lite i taget. Den här avhandlingen är ett av dessa steg.Min forskning är inriktad på atmosfärerna hos så kallade "ultra-hot Jupiters": planeter i Jupiters storlek som kretsar så nära sina stjärnor att de hettas upOne of the biggest questions people ask astronomers is whether life exists elsewhere in the universe. Unfortunately, we don’t yet have an answer. Instead, progress towards an answer comes in small, careful steps. This thesis is one of those steps.My research has focused on the atmospheres of "ultra-hot Jupiters": planets the size of Jupiter that orbit so close to their stars they are heated to tho
ZEISS LSM 800 with Airyscan Your Compact Confocal Power Pack Product Information Version 1.0 Click here to view this video 2 Confocal imaging demands the very best imaging quality. With LSM 800 you are choosing a flexible and compact confocal laser scanning microscope, complete with highly sensitive GaAsP detector technology and fast linear scanning. Add Airyscan, the revolutionary detection conce
https://www.ludc.lu.se/sites/ludc.lu.se/files/lsm_800_confocal_power_pack.pdf - 2026-05-09
In the post 9/11 era the effort to strengthen democracy in weak and fragile states has become a common undertaking of prominent international actors in their foreign policy agendas. In much of the academic and policy discourse democracy assistance has been framed as a solution to political instability and under-development in troubled states. With the case of the Middle East and North Africa regio
Every year about 15 million people are injured in traffic, 500,000 of these fatally. Developing countries are badly affected. During the worst years of the war in Nicaragua, more people died in traffic accidents than as a direct result of the war. Transport system and infrastructure have developed rapidly in developing countries, while little has been achieved in preventing accidents or lessening
Background: Whether and how n-3 and n-6 polyunsaturated fatty acids (PUFAs) are related to type 2 diabetes (T2D) is debated. Objectively measured plasma PUFAs can help to clarify these associations. Methods and Findings: Plasma phospholipid PUFAs were measured by gas chromatography among 12,132 incident T2D cases and 15,919 subcohort participants in the European Prospective Investigation into Canc
Background Following oesophagectomy, a major surgical procedure, it is known that patients suffer from severely reduced quality of life and have an unmet need for postoperative support. Still, there is a lack of research testing interventions aiming to enhance the patients’ life situation after this surgical procedure. Aim The aim of the study was to evaluate the effect of a nurse led telephone su
Internationella adoptioner började att ske efter andra världskriget för att hjälpa föräldralösa barn i krigsdrabbade länder och ökade senare i antal i samband med Vietnamkriget och Koreakriget. Det handlade främst om barnlösa par i Europa och USA som genom adoption ville rädda ett barn från hemländernas fattigdom. Det har dock framkommit att barn blivit illegalt adopterade, det vill säga adoptioneInternational adoption developed after the Second World War as an aid for orphaned children in war-torn countries and later on increased in numbers following the Vietnam War and the Korean War. The majority of adoptions concerned childless couples in Europe and the United States who through adoption wanted to save the child from poverty in its home country. International adoptions have however bee
Physical Properties of Prebiotic Membranes One of the most fundamental questions in science that remains unanswered today is the question of the origin of life on Earth. Life is defined as a chemical system with the capacity of self-replication and undergoing Darwinian evolution. Origin of life research focuses on the transition of physics and chemistry to such a chemical system. For life to ari
Gender-based violence survivors have barriers to access to justice around the globe. However, States are responsible for removing those barriers and ensuring that everyone can access needed services and justice without discrimination regardless of their gender, sexual orientation, race, nationality, disability, or age. Turkey is no exception with its international commitments and domestic laws to
Surrogatskap är en aktuell och omdebatterad fråga. Varken altruistiska eller kommersiella surrogatskap är tillåtna i Sverige. Surrogatskap är en relativt ny företeelse och diskuterades för första gången på 1980-talet i riksdagen. Till en början var de flesta partier restriktivt inställda och talade om surrogatskap som en främmande och osedlig företeelse. Med åren öppnades det dock upp för en diskuSurrogacy is a current and often debated issue. Neither altruistic nor commercial surrogacy is allowed in Sweden. When surrogacy was first discussed in the 1980s most parties were restrictive and spoke of surrogacy as a foreign and immoral phenomenon. Over the years, however, more parties have opened up for discussing the matter. In SOU 2016: 11, the possibility of surrogacy in Sweden was investi
37 § i lagen (1915:218) om avtal och andra rättshandlingar på förmögenhetsrättens område (AvtL) stadgar att avtal om förverkande av pant är ogiltiga. Syftet med bestämmelsen är att skydda gäldenären mot situationer där maktobalansen mellan den presumtiva pantsättaren och panthavaren är väldigt stor. Direktiv 2002/47/EG om ställande av finansiell säkerhet (säkerhetsdirektivet) syftar till fastställAgreements on forfeiture of pledged property are void, according to 37 § of the Swedish Contracts Act (1915:218). The purpose of the prohibition is to protect the debtor from situations where the power imbalance between the future pledgor and pledgee are palpable. Directive 2002/47/EC on financial collateral arrangements, objects to ensure that the parties may freely agree to a method of enforceme
