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Background: We have previously demonstrated that elevated concentrations of tumour-associated trypsin inhibitor (TATI) in both tumour tissue (t-TATI) and in serum (s-TATI) are associated with a poor prognosis in colorectal cancer patients. It was also found that s-TATI concentrations were lower in patients with rectal cancer compared to patients with colon cancer. In this study, we investigated th

Popular Abstract in Swedish När det blir stopp i ett av hjärtats kranskärl blockeras blodflödet till hjärtat, vilket kan orsaka blodbrist i en del av hjärtmuskeln. Detta kan i sin tur leda till hjärtinfarkt, vilket tar död på hjärtmuskelceller och skadar hjärtat. Vid den efterföljande behandlingen av hjärtinfarkt kan små proppar i kranskärlen, så kallade mikroembolier, ytterligare förvärra skadan Myocardial infarction (MI) following an acute coronary occlusion is a leading cause of morbidity and mortality. During revascularization, microemboli may complicate treatment and affect cardiac function. The long-term effects of microembolization are not fully elucidated. Following an MI it is important to accurately determine the size of the infarction, as it can be used for guidance in terms of

The reactor containment is one of the most important buildings at a nuclear power plant. In case of an accident the containment wall is the final protection against radioactive leakage to the surrounding environment. A reactor containment contains different types of concrete structures. They can be grouped as external structures constituting a barrier between the inside of the containment and the

In the US and most European countries, testicular cancer is the most common malignancy in young men aged 20-40 years. Since the introduction of cisplatin-based treatment in the 1970s, more than 95% of the patients are cured. The increasing incidence of testicular cancer and high survival rates, has led to a growing number of testicular cancer survivors (TCSs). As they have a long life expectancy i

Popular Abstract in Swedish Känselinformation (sensorisk information) från nacken har stor betydelse för rumsorienteringen. För att kunna detektera kroppsrörelser korrekt och därigenom bibehålla balansen krävs ett samspel mellan nackens sensoriska information tillsammans med kroppens övriga led- och muskelsinnen (proprioceptionen), balansapparaterna i inneröronen (vestibularisorganen), synen samt The overall aim of the work was to examine the influence of cervical biomechanical conditions on movement performance, to study musculoskeletal findings accompanying possible cervicogenic dizziness and to evaluate the influence of cervical proprioception on head orientation. Two devices, measuring cervical range of motion, were compared: Myrin, an inclinometer/compass method and Zebris®, a 3-dime

Differences between ages, sexes and populations in the timing of migration at Falsterbo, Sweden and in the choice of wintering site among raptors in Scania were investigated. Competition and dominance is the best primary explanation to the results. In most cases the more competitive adults winter north of juveniles and the larger females north of males. Moult strategy is probably one of the most i

A strain of an alkaliphilic bacterium Bacillus halodurans was isolated from a water sample in Lake Shalla, a soda lake in the Ethiopian Rift Valley. From the culture of this isolate, B. halodurans S7, a xylanase which is active in a wide range of pH, with an optimum at about 9-9.5 was purified. When assayed at pH 10, the enzyme was optimally active at 70 ?C. The xylanase was free from any associat

‘Safety pays’ is a phrase commonly used. But, when it comes to putting that concept into practice, very few are actually successful at it. Reasons given include: it is costly or it is a waste of time or it is not the main cause of failure. However the real problem is that there is not enough guidance as to how to improve safety performance on site. Traditional measurement approaches include accide

Between 1977 and 1996, cytogenetic investigations were performed on 182 childhood (< or = 16 yr) acute lymphoblastic leukemias (ALL), constituting 94% (182 of 194) of all ALL patients diagnosed and treated at the Departments of Pediatrics, Lund and Malmo University Hospitals, Sweden, during these two decades. The cytogenetic analyses were successful in 152 cases (84%). The failure rate was higher

Den svenska insolvensrätten har två tillvägagångssätt för företag som inte längre kan betala sina skulder, ett av dessa förfaranden är att bolaget blir föremål för företagsrekonstruktion. I samband med företagsrekonstruktioner drabbas inte minst arbetstagare som arbetar hos konkursgäldenären när deras lön och annan ersättning inte längre kan betalas ut. Inte sällan blir arbetstagarna uppsagda och Swedish insolvency law provides two procedures for companies that are no longer able to meet their financial obligations. One of these is corporate reorganisation. During such proceedings, employees of the insolvent company are often significantly affected, particularly when salaries and other compensation can no longer be paid. It is not uncommon for employees to be dismissed, and in some cases,

Fastställande av faderskap har historiskt haft stor betydelse i Sverige och varit avgörande för barns rättsliga och sociala ställning. Under lång tid gjordes en tydlig åtskillnad mellan barn födda inom och utom äktenskap, där barn utom äktenskap hade begränsade rättigheter. Sexuella relationer utom äktenskap var länge kriminaliserade och det kvarlevande stigmat kom även att prägla lagstiftningen oThe establishment of paternity has historically been of great significance in Sweden and has been decisive for children’s legal and social status. For a long time, a clear distinction was made between children born within and outside of marriage, where children born outside of marriage had limited rights. Sexual relations outside of marriage were long criminalized, and the lingering stigma also ca

Despite the average 5-year survival rate exceeding 85%, childhood cancer is still the most common cause of disease-related death among children in Sweden. A cancer diagnosis is profoundly traumatic not only for children themselves, but also for the entire family, particularly the primary caregivers, their parents. This project aimed to investigate the extent to which a childhood cancer diagnosis a

The gene fusion technique is widely used in protein engineering and in this thesis it constitutes the basis of both the construction of artificial bifunctional enzymes and the display of two novel peptides. Artificial bifunctional enzymes have been used as model systems in the studies of native multifunctional enzymes and proximity effects within these complexes. Two various constructs are descri

Wood is a hygroscopic material; always striving to reach equilibrium with the surrounding air, and consequently the moisture content is different in different climate conditions. The strength of wood is directly dependent on the moisture content, lower moisture content leads to increasing strength. Generally, state moisture equilibrium is seldom obtained because the moisture transport in wood is v

Popular Abstract in Swedish Epidemiologi är den vetenskap som studerar sjukdomars förekomst och spridning och hur detta varierar över tiden, mellan geografiska områden och mellan grupper av individer definierade i olika termer. I Malmö finns det mycket goda möjligheter att göra epidemiologiska studier av slaganfall (stroke). Dels finns ett register som följt strokeinsjuknandet sedan 1989. Dels harThe present thesis explored the epidemiology of stroke in Malmö, Sweden, an urban population of approximately 250000 inhabitants. Incidence of stroke in Malmö has been monitored since 1989. The National census investigation in 1990 was used to get information about the background population in the city. Previous studies of the seasonal and weekday variations in incidence of stroke have shown inco

It is well known that nature offers an abundance of materials and processes that can be adapted in low-tech fashion, to fabricate systems capable of removing pollutants from wastewater. During the last decade, extensive basic and engineering research on such natural treatment systems have led to improvement of the quality of discharged wastewaters. However, the mechanisms of natural treatment and

Endoscopic resection of colorectal polyps reduce morbidity and mortality from colorectal cancer (CRC).Endoscopic submucosal dissection (ESD) is a highly efficient and established method for treating advanced colorectal lesions in Asia, but experience of ESD in Western countries is limited. Large non-pedunculated colorectal lesions are prone to malignant transformation and it is therefore important

Background: Long-distance migration has evolved multiple times in different animal taxa. For insect migrants, the complete annual migration cycle covering several thousand kilometres, may be performed by several generations, each migrating part of the distance and reproducing. Different life-cycle stages and preferred orientation may thus, be found along the migration route. For migrating red admi