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Objective. The current study used islet amyloid polypeptide (IAPP) knockout mice (KO mice) to investigate the physiological role of IAPP in the regulation of food intake (FI). Material and methods. FI and body weight were measured in KO and wild-type (WT) mice for 27 weeks. In an additional short-term experiment, IAPP (25 pmol . kg(-1)min(-1)) was infused subcutaneously for 3 days in KO and WT mic

In light of heightened interest in the response of pollen phenology to temperature, we investigated recent changes to the onset of Betula (birch) pollen seasons in central and southern England, including a test of predicted advancement of the Betula pollen season for London. We calculated onset of birch pollen seasons using daily airborne pollen data obtained at London, Plymouth and Worcester, det

Background: We have previously demonstrated that elevated concentrations of tumour-associated trypsin inhibitor (TATI) in both tumour tissue (t-TATI) and in serum (s-TATI) are associated with a poor prognosis in colorectal cancer patients. It was also found that s-TATI concentrations were lower in patients with rectal cancer compared to patients with colon cancer. In this study, we investigated th

Many animal taxa have been shown to possess the ability of true navigation. In this study we investigated the possibilities for geomagnetic bi-coordinate map navigation in different regions of the earth by analysing angular differences between isolines of geomagnetic total intensity and inclination. In no-grid zones where isolines were running almost parallel, efficient geomagnetic bi-coordinate n

According to the UN, in 2050, 70% of the world’s population will live in cities. Already 10 % of those city residents live in mega-cities, such as Rio de Janeiro, with a population of more then 10 million people in its wider area. Thus, how to change the development path of cities and how to make them long-term sustainable becomes increasingly important. Lock-ins and complex intertwined issues of;

Silvernanopartiklars toxicitet i miljön – har storleken betydelse? Antibakteriella silvernanopartiklar (AgNP) används i en rad olika konsumentprodukter, men toxicitet och miljöeffekter är inte särskilt välförstådda. Frisättning av silverjoner (Ag+) visade sig vara viktigt för toxiska effecter på bakterier. Dock verkar faktorer i det omgiv-ande mediet, t.ex. vatten, också ha stor effekt på beteenBy the investigation of pollution induced community tolerance (PICT), this study aimed at elucidating whether or not ionic silver (Ag+) and silver nanoparticles (AgNP) differ in toxic mode of action. Specifically, bacterial communities in natural water underwent a 6, 7 or 14 day selection for tolerance to Ag+ or citrate-coated 20 nm AgNPs. Bacterial protein synthesis was measured by [3H]-leucine i

Both energy security and the demand for energy, particularly from renewable energy sources, as principle drivers, call for the investigation of renewable energy potential in Poland. The city of Zabrze, located in the Upper Silesia province and urban zone of Katowice, dedicates continuous efforts to the improvement of its waste management against the background of European Union Directives requirin

Finns det utrymme för kompakta bostäder i en hållbar stadsutveckling? Allt fler människor flyttar till städer. Det påverkar användningen av olika naturresurser men ökar också konkurrensen om mark – en resurs som inte är oändlig – då fler bosätter sig inom städernas begränsade områden. Trots att den genomsnittliga familjen minskat i storlek har bostäder å andra sidan blivit allt större. För att The Earth’s population is steadily increasing and there is a fast growing urbanization as people move from rural areas to cities. Lack of housing is a big issue in many cities. At the same time, dwellings are growing in size demanding more land and natural resources, a development which is not sustainable in the long run. That is problematic as it occupies land and requires natural resources, whic

Archaeology has always centred on material studies and has a long tradition of establishing methods for addressing the vast source material at hand. Typology is one of the most prominent of these methods, where the material is categorised into types according to morphology and geometry. There is an ongoing debate regarding the subjectivity of the typological approach and the problems that follow t

Om ett kärnvapen detoneras i atmosfären eller en allvarlig kärnkräftsolycka, likt Tjernobyl, inträffar kommer radioaktivt nedfall att ske. Nedfallet innehåller radioaktiva ämnen som kommer att spridas ut över ett stort område med vind eller nederbörd. Vid denna situation är det viktigt att kunna identifiera vilka radioaktiva ämnen som finns på marken samt vilken radioaktivitet dessa har för att kuIn the event of a nuclear weapon detonation or a power plant accident radionuclides will deposit on the ground. It is then important to identify and quantify the radionuclides to obtain information necessary for radiation protection efforts like relocation and decontamination. Radiation protection instruments with beta probes can be used as search instruments but the small surface of the probe an

Landskapsformen drumlin har länge diskuterats inom akademin och den här studen syftar till att sprida lite ljus över dom. Genom att kartlägga två drumlinområden runt sjön Åsnen i Småland, södra Sverige har deras utsträckning kartlagts med en precision som länge ansetts omöjligt. Detta gjordes genom att använda hög upplösta hillshade modeller framtagna från LiDAR data för att efter att ha analyseraThe landform group called drumlins has since long been enigmatic; this study aims to shed some light on them. By mapping their extent in two areas around Lake Åsnen, Småland, southern Sweden, their extent and prop-erties have been mapped with a level of detail that would have been next to impossible just a few years ago. The method used in this study utilized LiDAR derived high resolution hillshad

Sammanfattning Människohandel är en cynisk handel med möjlighet för förövarna att tjäna stora pengar. Risken att bli lagförd är relativt liten och straffen är förhållandevis låga. De stora orättvisorna i världen gör de utsatta människorna, främst kvinnor och barn, till ett lätt byte i denna industri. Visst finns möjligheten att tränga bort tanken att det skulle beröra oss, men den bittra sanningenSummary Human trafficking is a cynical trading with the opportunity for offenders to make big money. The risk to be tried in court is relatively small, and the penalty is relatively low. The vulnerable people in an unjust world, mainly women and children, become easy pray in this industry. We can pretend that this is not of our concern, but the bitter truth is the opposite. It is here, in the rich

The aim of this study is to investigate whether the choice of payment method in mergers and acquisitions is determined by the credit rating existence of the bidder and if the credit rating level has an impact of the financing source. The methods used are Probit and GLM logit regressions. The dependent variables are payment method and fraction of cash with credit rating and credit rating level as t

I Sverige berörs 200 barn per år av att en förälder utvisas ur landet. Barn har en del rättigheter dels genom vissa bestämmelser som finns i svenska lagar som FB, SOL och UtlL men även i EKMR och barnkonventionen. Möjligheterna att utesluta utvisning i ett mål kring utvisningsfrågan på grund av brott där utlänningen har barn i riket finner man främmst i 8kap 11§ UtlL. Denna lagändring infördes eftIn Sweden there are 200 children every year which is affected by a parent will be expelled from the country. Children have some rights partly through provisions in Swedish law such as FB, SOL and UtlL but also in EKMR and the child convention. The possibilities of limiting deportation order when the alien has children in the country are found mainly in the aliens act 8 chapters 11§. This provision

Now everything is different. Uncertain in a way. We have no idea where we’re going. It seems as if the explanatory models at our disposal aren’t even able to explain where we are today. The world is changing in a pace unprecedented in history. It seems extremely hard to understand how we’re supposed to orient ourselves in such a world. How are we supposed to dream? And what should we dream about?

Poly(arylene ether sulfone)s carrying various aromatic mono-, di-, and trisulfonated side´chains have been investigated with respect to their nanoscale structure and key membrane properties. Sulfobenzoyl, sulfonaphthoxybenzoyl, disulfonaphthoxybenzoyl, and trisulfopyrenoxybenzoyl side chains were attached to the poly(arylene ether sulfone) main chain by employing different combinations of metallat