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Molecular beacons (MBs) have been used on surfaces for detecting oligonucleotides. Attempts to use them intracellularly for monitoring mRNA content have been made, however, without any clear conclusion regarding the reliability of the method, mainly due to false positive signals. To reach an understanding of the intracellular fate of MBs, a critical question remains: how long after MB delivery and
ObjectivesBeing met with empathy increases information sharing, treatment coherence, and helps patients to recover faster. However, we do not know how the content of the conversation about disease progression, new treatments, or other issues concerning serious illness affects patients' perceptions of the physician's empathy, and thus, the quality of the conversation. This study aimed to test the h
In this work, we for the first time show that the geometrical magnetoresistance (gMR) effect is a powerful tool for extracting the carrier mobility in diffusive InGaAs near-surface quantum well MOSFETs. The technique shows excellent agreement to Hall effect measurements, confirming its validity. In addition, the gMR approach is less time-consuming, is suitable for measurements directly on the FETs
Serial dependence (SD) is said to occur when the judgment of a current stimulus is drawn toward a no longer relevant stimulus from the recent past. Working memory (WM) contributes to the ability to discriminate between irrelevant and relevant sensory impressions. How WM contributes to SD in facial identity remains to be fully understood. In the present study, we used a WM task with varying load in
The integration of coastal dunes planted with vegetation and dikes combines traditional infrastructure with dynamic aeolian sediment and ecological processes to enhance coastal resilience. The functioning of such dune-dike hybrid Nature-based Solution strongly depends on aeolian sediment transport and the vertical growth rate of vegetation. We used the AeoLiS numerical model to investigate the rel
Extensive ringing data from a coastal site (Falsterbo Bird Observatory) in southwesternmost Sweden were used to investigate the occurrence of reverse autumn migration among 20 passerine bird species oF widely different migration categories. The data demonstrate that reverse migration is a widespread and regular phenomenon among nocturnal as well as diurnal migrants and among irruptive migrants, te
Some plants use food bodies to attract ants that then provide protection from herbivory. A brief report from 1898 describes the myrmecophilic plant Leea aculeata Bl. as bearing food bodies on its young shoots, which accumulate when they are not harvested by ants. However, ant efficacy in deterring herbivores and consequences for herbivory rates remain unknown. Here we investigate (1) which ant tax
Purpose: Crisis planning and improvements to business resilience are increasingly significant aspects of hotel management. This study investigates the crisis preparation of hotel managers in Malaysia and how their perceptions affect crisis planning and preparation. Design/methodology/approach: A qualitative research method of semi-structured interviews with 24 hospitality managers in Malaysia was
The lifetime risk of developing atrial fibrillation (AF) is estimated to be between 1in 3 to 1 in 4 individuals, making it the most common arrhythmia in the world.For persistent AF, rate control drugs with the purpose to affect the conduction properties of the atrioventricular (AV) node are the most common treatment. The drug of choice varies between β-blockers and calcium channel blockers, often
Photo- and charge-carrier-induced ion migration is a major challenge when utilizing metal halide perovskite semiconductors for optoelectronic applications. For mixed iodide/bromide perovskites, the compositional instability due to light- or electrical bias induced phase-segregation restricts the exploitation of the entire bandgap range. Previous experimental and theoretical work suggests that exci
This paper addresses the topic of site characterization for the design of Shallow Geothermal Energy (SGE) systems, namely of thermoactive geostructures, which are geotechnical structures, such as piles, retaining walls and tunnel linings, also used as heat exchangers as part of closed-loop SGE systems. Such solutions, being increasingly adopted for buildings’ and infrastructures’ heating and/or co
Financial incentives offered to those who quit smoking have been found effective, also in persons with low socioeconomic status (SES), but no previous study has investigated who benefits most: smokers with low or high SES. In this community-randomized trial ("Richer without smoking"), three Danish municipalities were randomized to reward persons who were abstinent when attending the municipal smok
The first European Vasculitis Society (EUVAS) meeting report was published in 2017. Herein, we report on developments in the past 5 years which were greatly influenced by the pandemic. The adaptability to engage virtually, at this critical time in society, embodies the importance of networks and underscores the role of global collaborations. We outline state-of-the-art webinar topics, updates on d
BACKGROUND: Cytoreductive surgery with intraperitoneal chemotherapy has emerged as a new standard approach for peritoneal surface disease. This study investigated the learning curve of this combined modality treatment at a single institute.METHODS: Variables analysed over three consecutive treatment periods (1996-1998, 1999-2002 and 2003-2006) included number of abdominal regions affected, Simplif
In the promotion of energy efficiency in educational facilities, preschool children play an important role since simple energy-saving behaviour can be developed in early childhood. This study aimed to investigate the effects of behaviour interventions, with a particular focus on preschool children’s turn-off behaviour in shared environments. The intervention tools i.e. digital game, paper-board ga
Prader-Willi syndrome (PWS; MIM# 176270) is a neurodevelopmental disorder caused by the loss of expression of paternally imprinted genes within the PWS region located on 15q11.2. It is usually caused by either maternal uniparental disomy of chromosome 15 (UPD15) or 15q11.2 recurrent deletion(s). Here, we report a healthy carrier of a balanced X;15 translocation and her two daughters, both with the
In 2018, a strategy for Sweden's first National Forest Program was launched. As part of its implementation, County Administrative Boards have initiated dialogue processes for drafting regional forest strategies. Stakeholder deliberation is ascribed the potential to promote trust and mutual understanding, lead to more robust decisions and smoother implementation. We examine the dialogue processes,
How can peace be climate resilient? How can peace and environmental sustainability be advanced simultaneously? To address these questions, I develop a new conceptual and theoretical framework for climate resilient peace through degrowth. This paper calls for stronger consideration of positive conceptualizations of peace and of intersectionality and degrowth in pursuit of peace and resilience. Not
Frequent language exposure and use are among the most important conditions for successful language learning whether in classrooms, during study abroad, or in other informal contexts. Research probing exposure and usage often relies on one-off self-report questionnaires in which participants estimate their typical level of language exposure over extended periods of time, often long after it occurre
Type 1 diabetes (T1D) is a disease of insulin deficiency that results from autoimmune destruction of pancreatic islet β cells. The exact cause of T1D remains unknown, although asymptomatic islet autoimmunity lasting from weeks to years before diagnosis raises the possibility of intervention before the onset of clinical disease. The number, type, and titer of islet autoantibodies are associated wit
