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Optimization of fin configurations and layouts in a printed circuit heat exchanger for supercritical liquefied natural gas near the pseudo-critical temperature

In this study, the effects of fin configurations and layouts on thermal and hydraulic performances of printed circuit heat exchangers (PCHEs) with supercritical liquefied natural gas as the working fluid are studied by a numerical method, and the overall heat transfer performance of various parameters is evaluated by the JF factor. Firstly, the effect of four different airfoil configurations, i.e.

Substitution of metals in times of potential supply limitations: What are the mitigation options and limitations?

Global production rates of metals vary from iron at 1.4 billion ton per year to platinum with 200 ton per year. Resource scarcity starts to manifest itself in rising prices and supply limitations, and metal substitution has been a major argument among economists when putting considerations of resource scarcity aside. Here we investigate the potential limits to metal substitution. Present consumpti

Is one carbon price enough? Assessing the effects of payment vehicle choice on willingness to pay in Sweden

Existing knowledge suggests that people's willingness to pay (WTP) for climate change mitigation depends not only on personal characteristics but also on the payment vehicle (PV) that is used to elicit WTP. The aim of this research is to investigate policy-relevant differences in WTP between different PVs to support the design of carbon pricing mechanisms. The novelty of this contingent valuation

The Applicability of Mouse Models to the Study of Human Disease

The laboratory mouse Mus musculus has long been used as a model organism to test hypotheses and treatments related to understanding the mechanisms of disease in humans; however, for these experiments to be relevant, it is important to know the complex ways in which mice are similar to humans and, crucially, the ways in which they differ. In this chapter, an in-depth analysis of these similarities

Extraction of Multi-Labelled Movement Information from the Raw HD-sEMG Image with Time-Domain Depth

In contemporary muscle-computer interfaces for upper limb prosthetics there is often a trade-off between control robustness and range of executable movements. As a very low movement error rate is necessary in practical applications, this often results in a quite severe limitation of controllability; a problem growing ever more salient as the mechanical sophistication of multifunctional myoelectric

Unveiling the Ecological Applications of Ancient DNA from Mollusk Shells

The shells of marine mollusks represent promising metagenomic archives of the past, adding to bones, teeth, hairs, and environmental samples most commonly examined in ancient DNA research. Seminal work has established that DNA recovery from marine mollusks depends on their shell microstructure, preservation and disease state, and that authentic ancient DNA could be retrieved from specimens as old

Impact of sediment supply on decadal-scale dune evolution — Analysis and modelling of the Kennemer dunes in the Netherlands

This study investigates the impact of beach sediment supply on dune volume evolution through data analysis and model simulations of the Kennemer dunes in the Netherlands. A cross-shore sediment transport model (the CS-model) is applied with local time-averaged longshore sediment transport gradients derived from bathymetric and topographic observations. The model is used to study the relative impor

Biallelic somatic inactivation of the NF1 gene through chromosomal translocations in a sporadic neurofibroma

Neurofibroma is a benign tumor originating from Schwann cells in peripheral nerve sheaths and may occur as a sporadic tumor or as part of the dominantly inherited tumor syndrome NF1. NF1 is caused by constitutional mutations in the NF1 gene, located in chromosome band 17q11 Whereas the involvement of the NF1 gene in neurofibroma development in NF1 patients has been fairly well characterized, the s

Selective recovery of lactate dehydrogenase using affinity foam.

Selective isolation of lactate dehydrogenase (LDH) from porcine muscle extract was studied using foam generated from the vigorous stirring of a non-ionic surfactant, Triton X-114 derivatized with Cibacron blue. The cloud point of the surfactant-dye conjugate was higher than that of the native Triton X-114, and also the foam prepared from the affinity surfactant was more rigid taking a longer time

Detecting shifts of transmission areas in avian blood parasites - a phylogenetic approach

We investigated the degree of geographical shifts of transmission areas of vector-borne avian blood parasites (Plasmodium, Haemoproteus and Leucocytozoon) over ecological and evolutionary timescales. Of 259 different parasite lineages obtained from 5886 screened birds sampled in Europe and Africa, only two lineages were confirmed to have current transmission in resident bird species in both geogra

Meat intake and bladder cancer in a prospective study: a role for heterocyclic aromatic amines?

Objective The suspect carcinogens, heterocyclic amines (HAAs), found in well-done meat require host-mediated metabolic activation before inducing DNA mutations. The role of SULT1A1 and of NAT2 on the activation of HAAs suggests that NAT2 rapid acetylator genotype and SULT1A1 allele variants can have an effect on HAA carcinogenicity. Methods Data were collected as part of a case-control study neste

Analysis of developing and fully developed turbulent flow and heat transfer in a square-sectioned U-bend duct

Turbulent flow and thermal field were predicted in a square-sectioned 180° bend at a Reynolds number of 56000. Suga's low-Re cubic k-ε model [5-6] and the RSM [7-8] were used. The results were compared to experimental data [1]. Identical inlet boundary conditions were used in both cases. The inlet length impact on the flow-heat transfer in the bend was investigated. The velocities are higher near

Experimental Studies on Ambient Aerosol Hygroscopicity

Popular Abstract in Swedish Luften vi andas innehåller inte bara gaser som kväve och det syre vi behöver för att leva. Förutom de vanligaste gaserna i atmosfären finns det så kallade spårgaser, som visserligen har väldigt låg koncentration, men som har stor betydelse genom sina speciella kemiska och fysiska egenskaper. Koldioxid och ozon är exempel på sådana gaser. Förutom ozonets kraftiga oxideraThe air around us is full of aerosol particles which originate from a myriad of sources and which have vastly different chemical and physical properties. These particles span size ranges from 1 nm to 100 μm, equivalent to a factor 100 000 in diameter difference and a factor 10^15 in volume difference. They affect our health by depositing in our airways, worsening cardiovascular deceases, and they

Recipient and Donor Characteristics - Impact on Outcome after Heart Transplantation

Heart transplantation (HTx) is severely limited by a shortage of donors. This thesis aimed to investigate the effectof variables used to match donors to recipients in HTx.Methods: Data from the ISHLT registry was used to study: I: Identical versus compatible non-identical ABOmatchingin 3,589 AB HTx recipients. II: Outcomes of 94 ABO-incompatible transplants were compared to anABO-compatible group.

A novel optimization framework for designing multi-stream compact heat exchangers and associated network

Despite the performance gains of heat exchangers by thermal-hydraulic optimization, many design approaches suffer from a long process of trial-and-error, limited practical problem formulation and poor robustness. This paper addresses those challenges and develops an optimization framework for designing multi-stream compact heat exchangers. The optimization framework consists of a multi-stream matc

Metastasis therapies for renal cancer

Purpose of review Although novel targeted therapies for metastatic renal cell carcinoma (RCC) are emerging, metastasectomy still remains the only potentially curable intervention and plays an important role both in disease control, cancer-specific survival (CSS) and overall survival (OS). A systematic review was conducted in 2014 by the European Association of Urology RCC guidelines panel to summa