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Summary: Existing approaches to modelling antibody concentration data are mostly based on finite mixture models that rely on the assumption that individuals can be divided into 2 distinct groups: seronegative and seropositive. Here, we challenge this dichotomous modelling assumption and propose a latent variable modelling framework in which the immune status of each individual is represented along
In order to successfully produce food products containing less damaged particles (approx. 1 cm3) it is important to investigate at which limit that the particle could be subjected to processing. This study attempted to predict particle breakage using mechanical test with image analysis as method validation. The characterization of different coarse particles was done using the developed methods on
For magnetic field orientation of nonstructures to become a viable method to create high performance multifunctional nanocomposites, it is of paramount importance to develop a method that is easy to implement and that can induce long-range uniform nanostructural alignment. To overcome this challenge, inspired by low field nuclear magnetic resonance (NMR) technology, a highly uniform, high field st
Micelles play an important role in both experimental and computational studies of the effect of lipid interactions on biological systems. The spherical geometry and the dynamical behavior of micelles makes generating micelle structures for use in molecular simulations challenging. An easy tool for generating simulation-ready micelle models, covering a broad range of lipids, is highly desirable. He
Background The popularity of tattoos has increased dramatically over the last few decades. Tattoo ink often contains carcinogenic chemicals, e.g., primary aromatic amines, polycyclic aromatic hydrocarbons, and metals. The tattooing process invokes an immunologic response that causes translocation of tattoo ink from the injection site. Deposition of tattoo pigment in lymph nodes has been confirmed
Background: Timely and safe elective health care facilitates return to normal activities for patients and prevents emergency admissions. Surgery is a cornerstone of elective care and relies on complex pathways. This study aimed to take a whole-system approach to evaluating access to and quality of elective health care globally, using inguinal hernia as a tracer condition. Methods: This was a prosp
Robotic surgery was developed to expand the patient population being offered a minimal invasive approach while retaining the associated advantages of minimal invasive surgery. Robotic surgery has been suggested to be particularly beneficial in surgery for malignant disease or in the presence of extensive intraabdominal adhesion, severe endometriosis, large uteri, high burden of comorbidity, or obe
This review of a selection of literature in critical geography, political ecology, eco-Marxism, and ecological economics over thepast five decades reflects on the paucity of discussion on the phenomenon of modern, all-purpose money. This is paradoxical,given the almost universal denunciation of mainstream economics and capitalist political economy in this literature. The cri-tiques of environmental
Network analysis has been recently adopted by the field of psychology to explore networks of symptoms in psychopathology, and wider interactive networks of biological, behavioral, and psychological factors influencing mental health. The network theory of psychopathology conceptualizes symptoms of mental disorder as causally connected, rather than being caused by disease or an underlying latent var
INTRODUCTION: There are few recent studies on trends over time in functional outcome and mortality after stroke, with results separately presented for ischaemic stroke (IS) or ICH. We aimed to determine temporal changes in functional outcome and case-fatality 90 days after IS and ICH in Sweden between 2010 and 2019. PATIENTS AND METHODS: We included patients (≥18 years) with first-ever IS or ICH r
PURPOSE: To estimate the effect of dexamethasone eye drops on the risk of progression from type 2 retinopathy of prematurity (ROP) to ROP requiring traditional treatments.DESIGN: Register-based cohort study.PARTICIPANTS: Preterm infants born before 30 weeks' gestation from 2015-2018 (control years) and from 2020-2021 (intervention years) registered in the Swedish Quality Register for ROP at 4 Swed
We present the fabrication and characterization of single mode waveguides fabricated monolithically in SU-8. SU-8 is a negative resist, which can be structured by UV lithography followed by a baking step to induce cross-linking. As a material platform, SU-8 is well suited for systems used for biochemical analysis, as it possesses very high chemical resistance and good mechanical stability. Here we
A novel sliding vane rotary compressor with a rotating cylinder is proposed in this paper. The sliding vane dynamics analysis reveals that, compared with the traditional compressor, the friction loss at the sliding vane tips and between rotor and cylinder can be reduced to 0.25% and 10.23%. To numerically investigate the internal flow mechanism, a reliable three-dimensional simulation method is de
This study contains a series of laboratory experiments designed to describe the lateral movement and spatial variability of an infiltrated dye tracer across the capillary fringe of homogenous sand in an aquarium. A combination of image analysis and geoelectrical monitoring was used to track the flow paths of the dye with different hydraulic gradients and infiltration rates. Photographs were taken
The concept of acoustic comfort is hardly defined and used to refer to conditions of low noise levels or annoyance based on standardized descriptors. Airborne and impact sound measurements are used to rate acoustic comfort in dwellings, but they often do not express human perception of noise or comfort. If the descriptors are statistically associated with self-reported responses, they can be used
In order to be convergent, linear multistep methods must be zero stable. While constant step size theory was established in the 1950’s, zero stability on nonuniform grids is less well understood. Here we investigate zero stability on compact intervals and smooth nonuniform grids. In practical computations, step size control can be implemented using smooth (small) step size changes. The resulting g
