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A majority of all infectious diseases manifest some climate-sensitivity. However, many of those sensitivities are not well understood as meteorological drivers of infectious diseases co-occur with other drivers exhibiting complex non-linear influences and feedback. This makes it hard to dissect their individual contributions. Here we apply a novel deep learning Explainable AI (XAI) compartment mod

The presence of pharmaceuticals, especially antibiotics, in aquatic environments can significantly contribute to the rise of antibiotic resistance, presenting a critical global public health challenge. This study investigates the presence of four selected antibiotics and an antiretroviral drug (nevirapine) in the Vaal River in South Africa. Grab samples collected at nine sampling sites across four

Characteristic Mode analysis is a widely used technique in antenna design, providing insight into the fundamental electromagnetic behavior of radiating structures. In this paper, we establish fundamental bounds on the slope of characteristic mode eigenvalues and angles, demonstrating that their rate of change is subject to fundamental constraints for all possible realizations within a given design

Towards stem cell based therapies for Parkinson's disease SPOTLIGHT Towards stem cell based therapies for Parkinson’s disease Malin Parmar* ABSTRACT Treating neurodegenerative diseases with cell transplantation has been within reach since the first pioneering clinical trials in which dopamine neuron progenitors from the fetal brain were transplanted to individuals with Parkinson’s disease. However

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_development.pdf - 2026-07-15

Objectives: This study aims to investigate the inter-rater reliability and agreement of the diagnosis of otitis media with effusion, acute otitis media, and no effusion cases based on an otoscopy image and in some cases an additional wideband tympanometry measurement of the patient. Methods: 1409 cases were examined and diagnosed by an otolaryngologist in the clinic, and otoscopy examination and w

3D Gaussian Splatting (3DGS) has emerged as the latest breakthrough in 3D reconstruction since it can provide photorealistic 3D reconstruction with real-time rendering. Despite its increasing popularity, it lacks an accessible and clear end-to-end workflow, and the use for it in interactive and immersive applications remains largely unexplored. Furthermore, with the constant development of new 3DG

This thesis investigates the role of regime dynamics in sector-level asset returns. Based on the observation that financial markets exhibit structural changes that are not fully captured by standard linear factor models, this study examines whether incorporating regime information can improve the modeling and understanding of sector returns. Using US sector-level return data, an integrated framew

Limited-slip differentials (LSDs) are commonly used in high performance vehicles to im- prove handling by reducing differential speed and balancing torque between the driving wheels. BorgWarner develops electronically activated LSDs and Electric Cross Differen- tials (eXD), which dynamically control torque distribution to improve traction and vehicle performance. However, current electrically acti

Inom svensk forskning om läsundervisning har det framhållits att elever redan på mellanstadiet (åk 4-6) behöver utveckla litterär kompetens och få vägledning i hur de kan angripa och bearbeta en text för att utveckla fördjupad läsförståelse. Syftet med föreliggande artikel är att ge ett kunskapsbidrag beträffande hur undervisning som syftar till att utveckla förmågan att dra slutsatser om en skönlIn Swedish research on reading instruction, it has been emphasized that students already in middle school (grades 4-6) need to develop literary competence and receive guidance on how they can process a text in order to develop in-depth reading comprehension. The aim of the article is to contribute with knowledge regarding how teaching that aims to develop the ability to draw conclusions about a fi

Genome-wide screens using CRISPR/RNAi can identify new therapeutic vulnerabilities in prostate cancer. In this study, we combine DepMap functional screen data with a large gene expression database (N = 1012) and clinical outcomes to identify potentially druggable targets. Eight genes (CYC, CYP51A1, DHFR, EBP, KIF15, PPM1D, SQLE, and UMPS) demonstrated strong dependency in cell lines and were also

The thermal performance curve (TPC) of an organism captures how population growth depends on temperature. When populations experience increased temperatures, such as during global climate change, one prediction is that their TPC can evolve to accommodate the new environmental temperature. Although studies on TPC evolution have mostly focused on modifications in population growth rates, TPC evoluti

Recent years have seen an uptake in cycling and, with it, an increase in cyclists being involved in crashes. One particularly problematic area is that of urban signalised intersections, which are responsible for a majority of the crashes involving cyclists. One reason is the increased complexity at such locations. The bike box has been hailed as an infrastructure measure to help increase the safet

The ringing and controlling of previously marked birds are invaluable tools for studying the survival, productivity, and movement of birds. To maximize the value of ringing data, it is important to minimize any potential biases. For some species, such as nestbox-breeding owls, ringing records are typically heavily skewed toward females because they generally are easier to catch. The use of traditi

Shared entanglement can significantly amplify classical correlations between systems interacting over a limited quantum channel. A natural avenue is to use entanglement of the same dimension as the channel because this allows for unitary encodings, which preserve global coherence until a measurement is performed. Contrasting this, a distributed task based on a qubit channel is demonstrated, for wh

Visionen för upprening av antikroppar är att processen ska vara helautomatisk. Ofta eftersträvas en kontinuerlig process eftersom det i de flesta fall innebär lägre kostnader för produktionen och att utrustningen kan vara mindre. Det är nödvändigt att tillföra mer buffertlösning under processens gång, och som en del av visionen ska även detta göras automatiskt. Orbit är en mjukvara som används av The vision of antibody purification is to have the whole process fully automatic. It is often desirable to have a continuous process since that reduces the costs for production and the size of the used equipment. It is necessary to supply buffer solutions to the purification steps, and as part of the vision; this should be done automatically. An in-house piece of software called Orbit is used for

Devastating catastrophes during the 1980s together with recent years’ fatal accidents, including the Boeing 737 MAX plane crashes in 2018 and 2019, have altogether highlighted the need for researchers’ attention within the field of safety-critical systems. Additionally, as a result from technological advancement and globalization, the prevalent complexity and ambiguity within today’s systems conti

Wildlife crossing structures are needed to enable animal movements in an all more broken up landscape. The Swedish Transport Administration need to know how to build these. Previous studies have focused on passing frequencies and indices. Few have looked at the behavior of the visiting animals. In this study, I have complemented passage frequencies with vigilance behavior for roe deer and fallow d

Det finns många olika utformningar av lyfthjälpmedel och hjälpmedel för att gå, så som patient lyftar och rullatorer, men det finns inte många lösningar som kan göra båda. Detta examensarbete är baserat på en person med fysisk funktionsnedsättning som har specifika behov för vilka det inte fanns någon anpassad lösning. Målet var att utveckla en produkt som kan lyfta användaren från sittandes till

Familj och föräldraskap är relativt vanliga begrepp i våra liv. Deras innebörd i vardagliga sammanhang är dock betydligt mer omfattande än den rättsliga definitionen. I rätten har familjeband och föräldraskap historiskt sett grundats på äktenskap och genetik; moderskapet fastställs enligt Mater est-principen och faderskap genom presumtion, bekräftelse eller dom. Europakonventionen tillförsäkrar Family and parenthood are concepts commonly used in our day-to-day life, where the purports of the two also seem to be more including in comparison to the judicial definition. In legal history family ties and parenthood were marriage-based and due to reproduction. Maternity was simply a consequence of carrying a child while paternity would, in Sweden, be established by presumption, confirmation or