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Injurious loading of the joint can be accompanied by articular cartilage damage and trigger inflammation. However, it is not well-known which mechanism controls further cartilage degradation, ultimately leading to post-traumatic osteoarthritis. For personalized prognostics, there should also be a method that can predict tissue alterations following joint and cartilage injury. This chapter gives an
This study analyzes some of the factors that facilitate and complicate advanced legal teaching in human rights as a subject of international law. The main objective is to offer a reflection on the challenges faced by the teacher in this field and which arise as a result of the expansion, diversification, and confrontation of the subject taught. According to the argument developed, a classical or t
Low back pain is a leading cause of disability worldwide, putting a significant strain on individual sufferers, their families, and the economy as a whole. It has a significant economic impact on the global economy because of the costs associated with healthcare, lost productivity, activity limitation, and work absence. Self-management, education, and adopting healthy lifestyle behaviors, such as
Most proteins fold into characteristic three-dimensional structures. The rate of folding and unfolding varies widely and can be affected by variations in proteins. We developed a novel machine-learning-based method for the prediction of the folding rate effects of amino acid substitutions in two-state folding proteins. We collected a data set of experimentally defined folding rates for variants an
Brain organoid technology has transformed both basic and applied biomedical research and paved the way for novel insights into developmental processes and disease states of the human brain. While the use of brain organoids has been rapidly growing in the past decade, the accompanying bioengineering and biofabrication solutions have remained scarce. As a result, most brain organoid protocols still
Background: Recombination reshuffles alleles at linked loci, allowing genes to evolve independently and consequently enhancing the efficiency of selection. This makes quantifying recombination along chromosomes an important goal for understanding how selection and drift are acting on genes and chromosomes. Results: We present RecView, an interactive R application and its homonymous R package, to f
Solid organ transplant (SOT) recipients run a high risk for adverse outcomes from COVID-19, with reported mortality around 19%. We retrospectively reviewed all known Swedish SOT recipients with RT-PCR confirmed COVID-19 between March 1 and November 20, 2020 and analyzed patient characteristics, management, and outcome. We identified 230 patients with a median age of 54.0 years (13.2), who were pre
A new method for estimation of intragranular strain fields in polycrystalline materials based on scanning three-dimensional X-ray diffraction (scanning 3DXRD) data is presented and evaluated. Given an a priori known anisotropic compliance, the regression method enforces the balance of linear and angular momentum in the linear elastic strain field reconstruction. By using a Gaussian process (GP), t
OBJECTIVE: The aim of this exploratory randomised controlled trial (RCT) was to evaluate three different occupation-focused interventions for well older people by estimating effect sizes for leisure engagement and ability in activities of daily living (ADL) and thereby identifying the most effective interventions.METHODS: One hundred and seventy seven persons, 77-82 years old, living alone and wit
The present paper serves as an overview of recent developments by the author on the assessment and quantification of robustness of structures; the paper aims in this sense not to present any new results but collects approaches and results from previous publications. A general decision theoretical approach to the assessment and management of structural robustness is outlined. Structural robustness
Våldtäkt är ett utav de mest kränkande brott en person kan utsättas för och är ett ämne som ständigt upprör och leder till diskussion. Förhoppningsvis kan denna diskussion leda till att vi närmar oss en lösning som minskar våldtäkterna. En viktig del av lösningen är en effektiv lagstiftning. Idag grundar sig den svenska våldtäktbestämmelsen på tvång medan man i England och Wales valt att grunda deRape is one of the most offensive crimes a person can be subjected to and it is a matter that keeps aggravating and lead to discussion. Hopefully this discussion will lead us closer to a solution that will decrease the number of rapes. An important part of the solution is an effective legislation. Today the Swedish legislation regulating rape is based on force meanwhile the legislation in England
On January 1, 2009, new rules regarding limitations of the deductibility of intra-group interest payments came into force in the Swedish legislation. The rules aim to prevent the use of certain tax planning practices, where a company appropriates itself tax advantages by taking advantage of the unlimited right to deduct interest expenses. The tax advantage is ensued when the paying company makes a
Our purpose has been to examine their approach and experiences considering the work with needle exchange programs, as well as what perceptions the employees are experiencing from the society. We chose a qualitative approach to our study. In our study we have conducted six interviews with employees at needle exchange programs in three different cities in Skåne. We have asked questions such as what
Sammanfattning Denna pilotstudie hade som syfte att undersöka om ACT-baserad grupprehabilitering inklusive modifierad värderingskompass kunde öka deltagarnas förmåga att leva närmre sin värderade riktning inom områdena hälsa och sexuell hälsa. Mixad metod har använts med dels kvantitativ data från mätning med Distresstermometer, HADS, BIS och värderingskompass före, under och efter intervention ocAbstract The purpose of this pilot study was to examine if ACT-based grouprehabilitation with a modified Value Compass could enhance the participants capacity to live closer to their valued direction within the areas health and sexual health. The study used quantitative methods and qualitative methods to capture the experience of the intervention. The quantitative data was acquired with Distressth
Denna uppsats tar sikte på att undersöka var gränsen går för när någon annan än en gärningsman kan anses ha medverkat till brott. Medverkansansvar regleras i 23:4 BrB och föreskrivs den som med råd eller dåd främjat gärningsmannen i dennes otillåtna gärning. Råd eller dåd är ett gammalt juridiskt uttryckssätt som betecknar all form av intellektuell och fysisk verksamhet. Som utgångspunkt får såled
Medling är ett snabbt tvistlösningsförfarande med förhållandevis låga kostnader. En hög andel av alla medlingar som företas resulterar i överenskommelser som i stor utsträckning efterlevs av parterna. Mot bakgrund av medlingens förtjänster som tvistlösningsmetod undersöker uppsatsen, med fokus på kommersiella tvister, på vilka sätt medling kan främjas och i vilken utsträckning det är rättfärdigat
This exploratory investigation examines the Argentinian social movement for abortion rights, to provide material of strategies used by a successful social movement. By conducting interviews with participants of the movement, scholars, and representatives of feminist organisations in Buenos Aires, Argentina, the research gains first-hand insight to chart the strategies that were used. Assisting the
The aim of this study was to increase the knowledge of how school counselors describe what emotions can emerge while interacting with students, how they deal with their emotions when they emerge and the consequences of their emotion regulation. The study is based on semi-structured interviews with eight school counselors in Sweden who have had at least one six-month employment at a school. In our
