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Summary: Background: Diabetes mellitus (DM) is a risk factor for peripheral arterial disease (PAD). Indications for open surgery in infrainguinal intermittent claudication (IC) are limited, and reports are lacking regarding outcomes in DM patients. Study aims were to compare short and long-term effects on major adverse cardiovascular events (MACE), acute myocardial infarction (AMI), stroke, major

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BACKGROUND: The purpose of this study was to estimate precise age-specific tubo-ovarian carcinoma (TOC) and breast cancer (BC) risks for carriers of pathogenic variants in RAD51C and RAD51D. METHODS: We analyzed data from 6178 families, 125 with pathogenic variants in RAD51C, and 6690 families, 60 with pathogenic variants in RAD51D. TOC and BC relative and cumulative risks were estimated using com

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Hematopoiesis serves as a paradigm for how homeostasis is maintained within hierarchically organized cell populations. However, important questions remain as to the contribution of hematopoietic stem cells (HSCs) toward maintaining steady state hematopoiesis. A number of in vivo lineage labeling and propagation studies have given rise to contradictory interpretations, leaving key properties of ste

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Introduction: Although figure skating attracts several hundred thousand participants worldwide, there is little knowledge about physical health and sports injuries among young skaters. The present study aimed to describe the health status of a geographically defined Swedish population of licensed competitive figure skaters and to examine injury determinants. Methods: All licensed competitive skat

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Purpose: Although tumor infiltrating lymphocytes (TIL) assessment has been acknowledged to have both prognostic and predictive importance in triple negative breast cancer (TNBC), it is subject to inter and intra-observer variability that has prevented widespread adoption. Here we constructed a machine-learning based breast cancer TIL scoring approach and validated its prognostic potential in multi

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I have examined strategies which can compensate problems that music teachers diagnosed with ADHD meet in their professional role. Focusing on the teachers’ stories of creating solutions to get a functioning professional life, the results were produced by four qualitative interviews with teachers who themselves have ADHD. The study shows examples of how the teachers cope with their difficulties. Th

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Harmoniseringen av EU:s medlemstaters regelverk fortsätter på upphandlingsområdet. Medborgarnas intressen och värderingar har förändrats kraftigt sedan sekelskiftet. Som en effekt av globaliseringen och utvecklad informationsspridning har röster om bevarandet av mänskliga rättigheter fått allt starkare genomslagkraft. EU:s lagstiftare vill naturligtvis att medborgarnas värderingar i dessa frågor sThe interests and values of the EU member states have changed dramatically since the beginning of the century. As a result of globalization and the rapid spread of information, the need to support the preservation of basic human rights has become increasingly significant. The goals of EU legislators require that values of great importance held by the citizens should be reflected in the legislation

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The purpose of this study has been to investigate the service user involvement in the course “Socialt förändringsarbete” that has been offered since 2005 at the School of Social Work at Lund University. The service user involvement in this case is formed as an entire 7,5 hp course carried out by service users and social work students together. This means that the service users participate as stude

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In this thesis I analyze how the politicians of a small Swedish town experience the role of the city officials in the decision-making. This I do by interviewing several politicans in the City Council. I discuss what classical bureaucratic theories and theories about experts say about the officials’ role in the decision-making. I also include what the law says about the issue. The problems that occ

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The purpose of this essay is to give an image of the importance of humanitarian demining, it's difficulties and to what extent GPS can be a tool for this. A human rights perspective is used towards this through the entire work for what IMAS gives the parameters. GPS is a tool among others in the humanitarian demining process. GPS can be a tool in humanitarian demining especially in mapping min

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Syftet med denna studie är att undersöka hur olika energieffektiva renoveringsåtgärder kan påverka energiprestandan i äldre småhus. Studien omfattar en genomgång av tidigare forskning och en fallstudie av ett småhus byggt 1919, och undersöker effekten av tekniska åtgärder och olika användarbeteenden på energiprestanda. Fallstudien genomfördes med hjälp av simuleringsprogrammet IDA ICE. Det innebarThe purpose of this study is to investigate how different energy-efficient renovation measures may affect the energy performance of older detached houses. The study involves a review of previous research and a case study of one detached house built in 1919, and investigates the impact of technical measures and different user behaviors on energy performance. The case study was conducted by using th

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What factors contributed to the success of the Marshall Plan, and how did it impact postwar economic recovery and long-term development of Europe’s former Western bloc nations? What lessons can be learned from the Marshall Plan, and how can these lessons be applied to contemporary aid programmes for war-torn nations, such as Ukraine? Using a qualitative approach, analysing published research, the

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The rapid development of the technological world requires a corresponding adaptation in various industries. However, the construction industry is a step behind other industries when it comes to implementing new technical methods, and this is for several reasons. Some examples of these: 1. Conservative culture: For a long time, traditional construction methods have been an unwritten rule in the co

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Serious Games have gained increased attention in sustainability education. I developed a Serious Game that aims to increase sustainability competencies related to water problems among university students. I applied socio-constructivist learning theory to investigate how sustainability competency can be operationalised in learning outcomes and how these can be translated into game elements. Methodo

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Denna studie ämnar skapa förståelse för hur kommunikation sker på digitala plattformar. Genom det empiriska exemplet crowdfunding undersöks hur kommunikation gentemot investerare översätts till en delningsekonomisk kontext. Studien använder sig av en hermeneutisk ansats där empirin porträtteras i en flerfallsanalys. Kvalitativa intervjuer och dokumentanalys ligger till grund för analysen, i vilkenThis study aims to understand how communication occurs on digital platforms. Using crowdfunding as empirical evidence, the study examines how investor relations are translated into the context of the sharing economy. The study uses a hermeneutical approach where empirical data is portrayed in a multi-case analysis. Qualitative interviews and a document analysis form the basis of the analysis, in w

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Den här texten beskriver processen under vilken jag studerat mig själv som improvisationsmusiker i formatet solopiano. Jag undersöker hur jag skapar bästa möjliga förutsättningar för att känna mig både fri, inspirerad och motiverad, när jag inte får någon musikalisk information från andra medmusiker. Med hjälp av etablerandet av strikta ramar och begränsningar av olika karaktär har jag genomfört iThis paper describes the process during which I’ve studied myself as an improvisational musician in the format of solo piano. I examine in what way I can create the best possible conditions for myself to feel both free, inspired and motivated, when I’m not receiving any musical information from fellow musicians. With the help of different kinds of strict frames and limitations, I have performed im

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The thesis covers the relatively new area, talent forecasting, and how this work method has become an increasingly important tool in society where the demand for work possibilities increases. This leads to an increased need in knowledge and competence within society as well as in companies. Talent forecasting can be described as a work task with the purpose to predict what's coming, a forecast

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This study aims to examine the energy discourse and how it has changed in the Swedish climate debate through analyzing the closing debates prior the election of the Swedish government from Sveriges Television (SVT). The study also aspires to illuminate how sociocultural ideas of energy, climate and ways of living effects the discourse in the climate debate. The analytical framework is descriptive

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The purpose of the study was to investigate how social workers in the substance abuse and addiction services perceive collaboration with the psychiatric unit, and if the size of the municipality has a role in the extent to which collaboration takes place. A quantitative survey has been conducted with 40 respondents operating in a larger city and 15 respondents operating in a smaller city. The stud

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55 m.ö.h. på Balsbergets södra sluttning finner man en av Sydsveriges största grottor, Balsbergsgrottan. Ungefär 250 meter vindlande gångar grenar sig ut från två större salar. Grottan har en rik historia, både ur ett geologiskt och ett funktionalistiskt perspektiv. De sedimentära bergarterna som bildades för 100 miljoner års sedan lade grunden till, att det efter förra istiden kunde bildas en gro