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Determination of pK(a) values of titrating residues in proteins provides a direct means of studying electrostatic coupling as well as pH-dependent stability. The B1 domain of protein G provides an excellent model system for such investigations. In this work, we analyze the observed pK(a) values of all carboxyl groups in a variant of PGB1 (T2Q, N8D, N37D) at low and high ionic strength as determine

The stress field in a finite, edge cracked specimen under load is computed using algorithms based on two slightly different integral equations of the second kind. These integral equations are obtained through left regularizations of a first kind integral equation. In numerical experiments it is demonstrated that the stress field can be accurately computed. Highly accurate stress intensity factors

This report outlines the potential for a more structured and strategic relationship between the European Union and the Islamic Republic of Iran following the Joint Comprehensive Plan of Action (JCPOA). To both address areas of disagreement and complaints, as well as pursue common interests and matters of mutual benefit, the EU needs to put in place an institutional framework that can withstand the

Popular Abstract in Swedish För analys av agroekosystems näringsämnescirkulation presenteras här en generell modell. I centrum står födoproduktionsintensitet, mänsklig bärförmåga, uthållighet och effektivitet. Modellen kan användas på system med flera markanvändningstyper och är därför lämpad för studier i olika skalor. Jämförelser av alla slags agroekosystem, oavsett tid och rum, är möjliga. Olik

This work presented and optimization scheme for daylighting, heating and thermal comfort objectives in a highly insulated apartment, while varying different geometrical aspects of external windows (number, shape, size, position). To satisfy all objectives simultaneously, a large number of design iterations was evaluated by the use of the SPEA2 genetic algorithm as it is implemented on the Octopus

This paper argues that the concept of whistleblowing could best be understood as part of a larger regime of disclosure that includes personal revelations, truth-telling, leaking, informing, snitching and whistleblowing. Disclosure regimes are about knowledge that escapes. This paper discusses the conditions for this escaped knowledge and some of the consequences for organizations and communities.

An improved conventional-to-micro/minichannel criterion was proposed by using the Bond number and the liquid Reynolds number. In micro/minichannels, bubbles tend to be confined and elongated in the channel and the conventional two-phase flow theory loses its applicability. As significant disagreement in experimental trends and heat transfer mechanisms was reported for flow boiling in micro/minicha

I formulate a simple model of the ultimatum game, in which a proposer and a responder can receive a reward if they agree on how to divide this reward between them. The model is easy to analyse and shows that strong tendencies to fair division are expected when evolution of strategy frequencies follow the traditional gradient dynamics assumed in evolutionary models. The mean stable offer is typical

Latin hypercube sampling is suggested as a tool to improve the efficiency of different importance sampling methods for structural reliability analysis. In simple importance sampling, where the sampling centre is moved from the origin to the design point, standard Monte Carlo sampling can be replaced by Latin hypercube sampling. The efficiency improvement is then highly dependent on the choice of s

Forum Medicum ETT MEDICINSKT & HÄLSOVETENSKAPLIGT KUNSKAPSCENTRUM DÄR NUVARANDE HSC (HEALTH SCIENCES CENTRE) OCH BMC (BIOMEDICAL CENTRE) INTEGRERAS B il d : H en n in g L ar se n A rc h it e ct s 2 FORUM MEDICUM - DET NYA HÄLSOVETENSKAPLIGA OCH MEDICINSKA CENTRUMET Forum Medicum är Medicin- ska fakultetens vision om att samla den hälsovetenskap- liga och biomedicinska forsk- ningen och utbildninge

https://www.medicin.lu.se/sites/medicin.lu.se/files/forum_medicum_broschyr-ver_3_201612.pdf - 2026-06-08

LUIS | LUndS UnIverSItetS InnovatIonSSyStem Över 300 år av nyttig forskning 1707 | FRISKGÖRANDE VATTEN Medicinprofessorn och provinsialläkaren Johan Jacob Döbelius upptäckte och utvecklade Ramlösa hälsobrunn i början av 1700-talet. Enligt Döbelius botade det mineralrika vattnet från källan såväl skörbjugg och svindel som gikt och darrande leder. 1770 | NYA ORGANISKA SYROR Genom att frigöra organis

https://www.lu.se/sites/www.lu.se/files/innovationer_webb_sve.pdf - 2026-06-08

This paper assesses the performance of poverty alleviation projects, asks why so many have failed, and why successful projects have been successful. It gives a retrospective. overview of the development of the concept of poverty, and argues that the way towards poverty eradication goes through holistic, participatory, approaches that build on sharing of knowledge and learning by doing. Projects an

Purpose: The purpose of this study is to develop an understanding of consumers' perception of heritage in luxury brands online. This will be investigated from a consumer perceived value perspective, with regard to the following aspects of value; social, economic, functional and affective. Methodology: An epistemological and ontological foundation guides the research approach of qualitative so

I nuläget har textilkonsumtion en betydande negativ miljöpåverkan och behovet av hållbara konsumtionsmönster blir allt mer brådskande, konsekvent har modeindustrin en central roll i att främja förändring. För att hantera industrins utmaningar kring miljöpåverkan, utforskar denna studie styrkan i engagemang och community-byggande aktiviteter på Instagram. Studien som presenteras undersöker hur etCurrently, textile consumption has a significant negative environmental impact, and the need for sustainable consumption patterns is becoming increasingly urgent. Consistently, the fashion industry plays a central role in promoting change. To address the industry's challenges regarding environmental impact, this study explores the strength of engagement and community-building activities on Ins

Literature COSB31 2024 COSB31 China Today 7,5 ECTS First Cycle Spring Semester 2024 Books Joseph, William A. (ed.) (2019). Politics in China: An Introduction. Oxford: Oxford University Press (third edition). (Chapters: 1, 5, 6, 8 , 9, 10, 12, 14, 15) • Number of pages: 140 • Price: 399 kr (Ebook available) Garnaut, Ross, Ligang Song, and Cai Fang. China’s 40 years of reform and development: 1978–2

https://www.ace.lu.se/sites/ace.lu.se/files/2023-12/Literature%20COSB31%202024.pdf - 2026-06-08

Poly-N-isopropylacrylamide (PNIPAM) microgels are versatile colloidal-scale polymer networks that exhibit unique responsiveness to external stimuli, such as temperature. While the synthesis of PNIPAM microgels is well-documented, there is limited exploration of how their structural properties can be modified by subtle changes in the polymerization process. In this work, we carefully investigate ho

Josephson diodes are superconducting elements that show an asymmetry in the critical current depending on the direction of the current. Here, we theoretically explore how an alternating current bias can tune the response of such a diode. We show that for slow driving there is always a regime where the system can only carry zero-voltage dc current in one direction, thus effectively behaving as an i