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Uncertainty analysis should be an integral part of conducting a scientific investigation of the damaging human health effects of exposure to chemicals. Sources of uncertainty related to limitations in knowledge are present in all steps of a such risk assessment, i.e. the hazard identification, hazard characterization and exposure assessment. The purpose of uncertainty analysis is to evaluate the c
Background: Severe left-sided cardiac obstructions are associated with high morbidity and mortality if not detected in time. The correct prenatal diagnosis of coarctation of the aorta (CoA) is difficult. Fetal cardiac magnetic resonance imaging (CMR) may improve the prenatal diagnosis of complex congenital heart defects. Flow measurements in the ascending aorta could aid in predicting postnatal Co
Traditionally the simulation of transient and voltage stability in power systems has been constrained to tools developed specifically for this purpose, e.g. Simpow, PSS/E, ETMSP and Eurostag. While being efficient and thereby able to simulate large systems, their component models are often encapsulated and difficult or impossible to examine and modify. Also, these simulators often require substant
The first part of this study focuses on the effect of cone calorimeter test variables on polyurethane flexible foam properties such as ignitability, heat release rate, effective heat of combustion and mass loss. Three of the main commercial foam types were used, i.e. conventional slabstock foams, high‐resilience slabstock foams and all‐MDI (methylene diphenyldiisocyanate) moulded foams. A decrease
The first part of this study focused on the effect of cone calorimeter test variables on polyurethane flexible foam properties such as ignitability, heat release rate, effective heat of combustion and mass loss. Three of the main commercial foam types were used; viz. conventional slabstock foams, high resilience slabstock foams and all-MDI moulded foams. A decrease in heat flux (down to 40%) with
Bai Nuur (41 degrees 38.590'N, 114 degrees 30.922'E, similar to 1346 m a.s.l.) and Ulan Nuur (41 degrees 44.214'N, 115 degrees 05.630'E, similar to 1246 m a.s.l.) are two small lakes situated in the transition zone between semi-humid and semi-arid climate regimes that runs parallel to the present limit of the southeast monsoon along the southeastern Inner Mongolia Plateau in north China. A 215 cm-
IMPORTANCE The introduction of biological tumor necrosis factor inhibitors has improved the treatment of rheumatoid arthritis (RA) but at a substantial cost. These drugs have been shown to lead to superior radiological outcomes compared with a combination of conventional disease-modifying antirheumatic drugs over 2 years. OBJECTIVE To investigate whether radiological superiority translates into be
First, we study geometric variants of the standard set cover motivated by assignment of directional antenna and shipping with deadlines, providing the first known polynomial-time exact solutions. Next, we consider the following general (non-necessarily geometric) capacitated set cover problem. There is given a set of elements with real weights and a family of sets of the elements. One can use a s
Food production and consumption have a range of sustainability implications, including their contribution to global emissions of greenhouse gases (GHGs). As some foodstuffs entail higher GHG emissions than others, managing their use in tourism-related contexts could make a significant contribution to climate change mitigation. This article reviews the carbon intensity of selected foods and discuss
In this 24-month follow-up of a phase II study in patients with castration-resistant prostate cancer (CRPC) and bone metastases, radium-223 (4 injections of 50 kBq/kg every 4 weeks [n = 33]) improved median overall survival vs. matching placebo (n = 31) (65.3 vs. 46.4 weeks, respectively; log-rank P = .056), with no long-term safety concerns. Data suggest that treatment of bone disease with radium
Lately, much work in the area of voltage stability assessment has been focused on finding post-contingency corrective controls. In this article a contribution to this area will be presented where we search for maximal loadability while considering post-contingency corrective controls. This objective is different from the usual approach to the problem, where the aim is to include the post-contingen
Recent progress in the study of surfactant-responsive polymer gels is reviewed. Polymer gels can be designed that drastically swell or shrink in response to small changes in the concentration of an ionic surfactant in an external bath containing the gel. The gel swelling isotherm, where the equilibrium gel volume is measured as a function of the external surfactant concentration, yields useful inf
Popular Abstract in Swedish Att klara sig trots allt: Den sociala och produktiva dynamiken hos småbönderna i de halvtorra områdena i Iringa i norra Tanzania. Det är inte lätt att överleva som småbonde i de halvtorra områdena i Iringa och på liknande platser i Afrika. Man kontrollerar knappast sin egen livssituation. Regnen är opålitliga, priser, marknadsföring och politiska ingrepp är oförutsägbaWhile much of semi-arid Africa is still sparsely populated with unused land, there are everywhere pockets of high and increasing population density in attractive locations. Small-scale farmers can respond to beginning land-scarcity in a number of ways. Through migration, through diversification of livelihoods, or through changes in their farming system. Which solution is chosen, depends not only o
Applying the concept of virtual history, it is possible to reconcile the Soviet history of East Prussia with what came before not only by writing history in a conciliatory and objective manner, but also by presenting the past as one. With this I mean that it is possible to transcend the time dimension and to supersede the notion of history as a chain of events. History need not be written in books
Popular Abstract in Swedish Tillväxthormon (GH) insöndras stötvis från hypofysen. Insöndringen är som högst nattetid, och de högsta nivåerna ses under puberteten för att därefter avta succecivt med ökande ålder. En av de vanligaste orsakerna till brist på GH är godartade tumörer i hypofys och hypofysnära områden där även behandling med kirurgi och strålbehandling kan bidra till hypofysinsufficiensIn childhood onset growth hormone deficiency (GHD) a reduction in cardiac left ventricular mass (LVMi) and impairment of cardiac systolic function, as well as in glomerular filtration rate (GFR) has been shown. In study I, we showed that a low dose of GH treatment for 10 months resulted in increased LVMi and kidney size. No significant improvement in cardiac systolic function or GFR, except for a
A group of Swedish radiation oncologists and hospital physicists have estimated the number of patients in Sweden suitable for proton beam therapy in a facility where one of the principal aims is to facilitate randomized and other studies in which the advantage of protons can be shown and the magnitude of the differences compared with optimally administered conventional radiation treatment, also in
Valence-band structure and magnetic properties, especially magnetic anisotropies, in the (Ga,Mn)As diluted ferromagnetic semiconductor are shortly discussed. Next, magneto-resistive, cross-like nanostructures fabricated by electron-beam lithography patterning and chemical etching from thin (Ga,Mn)As epitaxial layers are described. The nanostructures, composed of two perpendicular nanostripes cross
Objective: No method has yet been established to summarise different objective indicators of social outcomes into one score. The study aimed to develop and test a simple, brief and meaningful index of social outcomes that can be used across a broad range of mental health studies and is potentially obtainable from routine documentation. Method: An index capturing employment, accommodation and livin
AIMS: To determine the basal pharmacokinetics, lung uptake and plasma cortisol suppression for two commonly prescribed inhaled corticosteroids. METHODS: Twenty-one subjects (13 healthy and 8 mild asthmatic patients) received fluticasone propionate via a chlorofluorocarbon-propelled pressurized metered-dose inhaler (pMDI) (healthy subjects only) and Diskus and budesonide via Turbuhaler, 1000 microg
