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Molecular dynamics (MD) simulations contain considerable information with regard to the motions and fluctuations of a protein, the magnitude of which can be used to estimate conformational entropy. Here we survey conformational entropy across protein fold space using the Dynameomics database, which represents the largest existing data set of protein MD simulations for representatives of essentiall

Burning candles release a variety of pollutants to indoor air, some of which are of concern for human health. We studied emissions of particles and gases from the stressed burning of five types of pillar candles with different wax and wick compositions. The stressed burning was introduced by controlled fluctuating air velocities in a 21.6 m3 laboratory chamber. The aerosol physicochemical properti

Non-exhaust emissions, generated by the wear of brake systems, tires, roads, clutches, and road resuspension, are responsible for a large part of airborne pollutants in urban areas. Brake wear accounts for 55% of non-exhaust emissions and significantly contributes to urban health diseases related to air pollution. A major part of the studies reported in the scientific literature are focused on exp

Objective: To evaluate the test–retest reliability of the Life Satisfaction Questionnaire (LiSat-11) and the association between items in individuals with chronic stroke. Design: Test–retest design. Subjects: Forty-five individuals (mean age 65 years) with mild to moderate disability at least 6 months post-stroke. Methods: LiSat-11, which includes 1 global item”Life as a whole” and 10 domain-speci

Transcriptional profiling of acute leukemia, specifically by RNA-sequencing or whole transcriptome sequencing (WTS), has provided fundamental insights into its underlying disease biology and allows unbiased detection of oncogenic gene fusions, as well as of gene expression signatures that can be used for improved disease classification. While used as a research tool for many years, RNA-sequencing

The vascular effects of endogenous substances can be eas- ily studied in the skin. Early in this century vasoregulation was shown to be dependent on innervation. Peptidergic trans- mitters have been shown to coexist and cotransmit along with noradrenalin and acetylcholine, sometimes being responsi- ble for non-adrenergic-non-cholinergic responses. This review summarizes recent info

Summation-By-Parts (SBP) methods provide a systematic way of constructing provably stable numerical schemes. However, many proofs of convergence and accuracy rely on the assumption that the SBP operator possesses a particular eigenvalue property. In this note, three results pertaining to this property are proven. Firstly, the eigenvalue property does not hold for all nullspace consistent SBP opera

In laser spectroscopy, high photon flux can perturb the sample away from thermal equilibrium, altering its spectroscopic properties. Here, we describe an optical beam scanning apparatus that minimizes repetitive sample excitation while providing shot-to-shot sample exchange for samples such as cryostats, films, and air-tight cuvettes. In this apparatus, the beam crossing point is moved within the

Quantifying air-borne and structure-borne sound insulation is an important design consideration for the indoor comfort in a building. Although sound insulation performance is commonly measured experimentally, numerical methods can have time-saving and economic benefits. Further, numerical methods can be incorporated within building simulations to provide an estimate of the acoustic environment. In

The extracellular matrix (ECM) is not just a 3 dimensional scaffold that provides stable support for all cells in the lungs but is also an important component of chronic fibrotic airways, vascular, and interstitial diseases. It is a bioactive entity that is dynamically modulated during tissue homeostasis and disease, which controls structural and immune cell functions, drug responses, and which ca

Welfare capitalism has developed in the context of rapidly expanding, fossil fuel-driven industrial economies. Faced with the urgent need for systematic changes of economic systems so that they stay within planetary limits, decoupling welfare from economic growth is an important task. This chapter introduces the concept of sustainable welfare, referring to welfare systems that prioritise the satis

The aim of the project is the reconstruction of the district Bento Rodrigues located in the state of Minas Gerais; Brazil destroyed by the collapse of a mining dam Fundão in November 2015. This disaster was one of the biggest tragedy in the country. Mud covered the village, a river flooded and all the waste arrived until the Atlantic Ocean, including one of the most important rivers, the Rio Doce.

In addition to various switch and track materials, Vossloh Nordic Switch Systems AB have a wayside lubrication device, Clicomatic© in their product range. Clicomatic© is a lubricator intended for fixed installation to mainly lubricate the railway track at exposed sections. Its purpose is to apply grease in the active interface between the vehicle and the track. Clicomatic© was developed decades ag

Det nyligen antagna direktivet om tillräckliga minimilöner i Europeiska unionen har resulterat i en oro på den svenska arbetsmarknaden. Med tanke på motståndet är det aktuellt att undersöka vilken påverkan direktivet kommer att ha på den svenska lönebildningsmodellen och om det stämmer att kollektivavtalssystemet riskerar att urholkas. Fokus ligger på om direktivet kommer att påverka arbetsmarknadThe recently adopted directive on adequate minimum wages in the European Union has raised voices of concern on the Swedish labour market. With the resistance in mind it is relevant to explore what impact the minimum wage directive will have on the Swedish model of formation of wages and if the model really is at risk of being undermined. The focus of the essay is set to investigate what impact the

Plastics play a central role in our society today and are omnipresent. Compost frommgarden waste is used in gardening as a soil amendment. This circular use of plants, branches and other green waste is a way to reduce the use of linear resources for soil amendment, such as peat. A problem that can arise when using compost is the spread of plastic particles from the garden waste to the environment.

This project discusses the effects of recycle streams on the dynamics and performance of chemical plants. The questions addressed are: can the current industry standard tuning methods still be applied to systems with recycle, and if not, how can they be modified? This is approached by analysing the arrest time tuning method when applied to an integrating process with and without recycle. The resul