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Impact of beam angle choice on pencil beam scanning breath-hold protontherapy for lung lesions

Introduction:The breath-hold technique inter alia has been suggested to mitigate the detrimental effect of motion on pencil beam scanned (PBS) proton therapy dose distributions. The aim of this study was to evaluate the robustness of incident proton beam angles to day-to-day anatomical variations in breath-hold.Materials and methods: Single field PBS plans at five degrees increments in the transve

It Takes Two Planets in Resonance to Tango around K2-146

K2-146 is a cool, 0.358M⊙ dwarf that was found to host a mini-Neptune with a 2.67 day period. The planet exhibited strong transit timing variations (TTVs) of greater than 30 minutes, indicative of the presence of an additional object in the system. Here we report the discovery of the previously undetected outer planet in the system, K2-146 c, using additional photometric data. K2-146 c was found t

Self-Reported Shorter Than Desired Ejaculation Latency and Related Distress—Prevalence and Clinical Correlates : Results From the European Male Ageing Study

Background: Few data have looked at the occurrence and clinical correlates of self-reported shorter than desired ejaculation latency (rapid ejaculation, RE) and its related distress in the general population. Aim: To determine the prevalence and clinical correlates of self-reported RE and RE- related distress in middle age and older European men. Methods: Subjects were recruited from population sa

Transcriptional and Epigenetic Changes Influencing Skeletal Muscle Metabolism in Women With Polycystic Ovary Syndrome

Context: Insulin resistance in skeletal muscle is a major risk factor for the development of type 2diabetes in women with polycystic ovary syndrome (PCOS). Despite this, the mechanisms underlyinginsulin resistance in PCOS are largely unknown.Objective: To investigate the genome-wide DNA methylation and gene expression patterns inskeletal muscle from women with PCOS and controls and relate them to

Clinical diversity and treatment results in tegumentary leishmaniasis : A European clinical report in 459 patients

Background Cutaneous leishmaniasis (CL) is frequent in travellers and can involve oro-nasal mucosae. Clinical presentation impacts therapeutic management. Methodology Demographic and clinical data from 459 travellers infected in 47 different countries were collected by members of the European LeishMan consortium. The infecting Leishmania species was identified in 198 patients. Principal findings C

The Impact of Different Drying Techniques and Controlled Storage on the Development of Advanced Glycation End Products in Skim Milk Powders Using Isotope Dilution ESI-LC-MS/MS

The impact of different drying techniques and storage conditions on the formation of carboxymethyl lysine (CML) as an advanced glycation end product (AGE) was investigated in various pilot-scale produced skim milk powders (SMP). CML, an indicator of advanced stages of the Maillard reaction, was analyzed by isotope dilution ESI-LC-MS/MS after drying and at intervals during storage for 200 days. The

Activation of complement by pigment epithelium-derived factor in rheumatoid arthritis

The aim of this study was to identify molecules that trigger complement activation in rheumatic joints. C4d, the final cleavage product of C4 activation, is found in the diseased joint and can bind covalently to complement-activating molecules. By using a highly specific Ab against a cleavage neoepitope in C4d, several molecules that were specifically bound to C4d were identified from pooled synov

When geophysics met geomechanics: Imaging of geomechanical properties and processes using elastic waves

Geophysics measurement techniques can be considered as non-destructive, remote methods to analyse the physical properties of geologic materials hidden at depth in the earth, within geotechnical structures or within laboratory test specimens. The objective of this paper is to highlight at least some of the potential to use geophysics methods to aid geomechanical investigations, both at the laborato

Indoor Particle Concentrations, Size Distributions, and Exposures in Middle Eastern Microenvironments

There is limited research on indoor air quality in the Middle East. In this study, concentrations and size distributions of indoor particles were measured in eight Jordanian dwellings during the winter and summer. Supplemental measurements of selected gaseous pollutants were also conducted. Indoor cooking, heating via the combustion of natural gas and kerosene, and tobacco/shisha smoking were asso

Designing erosion management plans in Lebanon using remote sensing, GIS and decision-tree modeling

Soil erosion by water represents a serious threat to the natural and human environment in Mediterranean countries, including Lebanon, which represents a good case study. This research deals with how to use Geographic Information Systems (GIS), remote sensing, and, more specifically, structural classification techniques and decision-tree modeling to map erosion risks and design priority management

Low-Dose Oral Ketamine for Procedural Analgesia in Pediatric Cancer Patients Undergoing Lumbar Puncture at a Resource-Limited Cancer Hospital in India

Aim: The aim of this study was to evaluate the therapeutic efficacy and safety profile of orally administered low-dose ketamine for procedural pain management in pediatric cancer patients undergoing lumbar puncture (LP) in a resource-limited hospital setting. Methods: Patients between 4 and 15 years of age, with leukemia, undergoing LP were asked to participate. The study was designed as a two-a

The European Butterfly Indicator for Grassland species: 1990-2015

This report presents the sixth version of the European Grassland Butterfly Indicator, one of the EU biodiversity indicators of the European Environment Agency.The indicator is based on more than 9200 transects in national Butterfly Monitoring Schemes covering 22 countries across Europe, most of them active in the European Union. In 2015, counts were made in more than 4500 transects.Butterflies rep

Evaluation of single-fraction high dose FLASH radiotherapy in a cohort of canine oral cancer patients

Background: FLASH radiotherapy (RT) is a novel method for delivering ionizingradiation, which has been shown in preclinical studies to have a normal tissuesparing effect and to maintain anticancer efficacy as compared to conventionalRT. Treatment of head and neck tumors with conventional RT is commonlyassociated with severe toxicity, hence the normal tissue sparing effect of FLASHRT potentially ma

Optimering av sulfatinnehållet hos blandcement

Optimering av sulfatinnehållet hos blandcement Betong är ett av världens mest använda byggnadsmaterial, men visste du att betongindustrin står för hela 5-8 % av världens totala koldioxidutsläpp? Tillverkningen av cementet till betongen står för en stor andel av utsläppen, men det finns material som kan ersätta en del av cementet för att ta fram mer miljövänliga blandcement.Abstract The production of concrete has a large environmental impact because of the carbon dioxide emissions from cement production. To reduce emissions of carbon dioxide, part of ordinary portland cement can be replaced with different supplementary cementitious materials to create blended cements. Supplementary cementitious materials are often waste products from other industries, such as fly as

Det brukande folket och den goda jorden: Skåningarnas relation till marken som föder dem

The purpose of this thesis is to describe and analyze the development of the agriculture in the county of Skåne (Scania) and to see if there are explanations to be found why the agricultural land is exploited today. By theories from human ecology I discuss the interconnections between human, nature and society both in a historical and a present perspective. Focus is on how the landscape, humans an

Personal branding – möjlighet eller krav?

Sammanfattning Examenarbetets titel: Personal branding – möjlighet eller krav? Seminariedatum: 2015-01-15 Ämne/kurs: FEKH29 Företagsekonomi: Examensarbete i marknadsföring på kandidatnivå, 15 högskolepoäng Författare: Magnus Skog, Justus Jahja, Niran Ahmad Handledare: Jon Bertilsson Nyckelord: Sociala medier, varumärke, företagsledare, finansiellt resultat Syfte: Uppsatsens syfte är att i eAbstract Title: Personal branding – opportunity or necessity? Seminar date: 2015-01-15 Course: FEKH29 Business administration: Degree Project in Marketing, Undergraduate Level, 15 hp. Authors: Magnus Skog, Justus Jahja, Niran Ahmad Advisor: Jon Bertilsson Key words: Social media, brands, Ceo, financial result Objective: The objective of this thesis is to in an explorative approach obtain th

Combination of acoustic trapping and impedance spectroscopy for platelet analysis

A combination of acoustic trapping and impedance spectroscopy for micrometer-sized objects is here presented for the first time. Acoustic trapping has proven to be a well-functioning method for non-contact immobilization and positioning of particles or cells in microfluidic channels. The combination with impedance spectroscopy allows for simultaneous electrical measurements on the trapped objects.

Method Development for Fractionation of Milk Fat Globules -For improvement of cream functionality

In recent years, different methods for fractionation of native milk fat globules with respect to particle size have been developed. This has been done in order to investigate if the size of the fat globules have any impact on the product functionality. The purpose of this master thesis was to develop a method for fractionation of native milk fat globules with respect to particle size and with focu