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Inhibition of IL-4Rα reduces CCL26 in bronchial epithelial cells from COPD patients

Background Anti-interleukin (IL)-4Rα monoclonal antibodies (mAb) improve lung function and decreasethe number of exacerbations in patients with COPD type (T) 2 inflammation. However, the involvement ofearly innate immune responses underlying these treatment effects is not well known. We sought tounderstand the effect and mechanisms of IL-4Rα mAb treatment on bronchial epithelial cells (BECs) fromCBackgroundAnti-IL-4Rα monoclonal antibodies (mAb) improve lung function and decrease the number of exacerbations in patients with COPD type (T) 2 inflammation. However, the involvement of early innate immune responses underlying these treatment effects is not well known. We sought to understand the effect and mechanisms of IL-4Rα mAb treatment on bronchial epithelial cells from COPD patients under

LL SMAA40 eng HT22 220525 revDekker 220614

https://www.ses.lu.se/en/sites/ses.lu.se.en/files/2022-06/LL_SMAA40_eng_HT22_220525_revDekker_220614.pdf - 2026-06-20

LL SMAA40 eng HT22 220525

https://www.ses.lu.se/en/sites/ses.lu.se.en/files/2022-05/LL_SMAA40_eng_HT22_220525.pdf - 2026-06-20

No title

Crystal structure and substrate interactions of an unusual fungal non-CBM carrying GH26 endo-β-mannanase from Yunnania penicillata

The Role of Small-Bowel Capsule Endoscopy in the Diagnostic Algorithm of Complicated Perianal Disease

Introduction: Complicated perianal disease (cPD) may be the sole presentation of Crohn’s disease (CD). The role of small-bowel capsule endoscopy (SBCE) in the diagnostic algorithm of cPD is unclear. We aimed to evaluate the role of SBCE as a diagnostic tool, in patients with cPD, after a negative standard workup for CD. Methods: A multicenter, retrospective, cross-sectional study, in patients with

Structural and Biochemical Analyses of Glycoside Hydrolase Families 5 and 26 beta-(1,4)-Mannanases from Podospora anserina Reveal Differences upon Manno-oligosaccharide Catalysis

Persistence of hSBA titers elicited by the meningococcal serogroup B vaccine menB-FHbp for up to 4 years after a 2- or 3-dose primary series and immunogenicity, safety, and tolerability of a booster dose through 26 months

Safety and convenience of once-weekly somapacitan in adult GH deficiency: a 26-week randomized, controlled trial

Over-expression, purification and characterization of a β-mannanase BoMan26B from Bacteroides ovatus

Hemicelluloses account for 25-30% of total wood dry weight. Mannan-based polysaccharides are the major component of softwood hemicelluloses. They are characterized by their β-1,4-glycosidic linked backbone composed of mannose or a combination of mannose and glucose residues. The backbone can be substituted by α-1,6-linked galactose residues. β-mannanases cleave the internal β-1,4-glycosidic bonds

Birtele et al-2019-febs letters

Dual modulation of neuron‐specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/birtele_et_al-2019-febs_letters.pdf - 2026-06-20

Metformin-induced suppression of Nemo-like kinase improves erythropoiesis in preclinical models of Diamond–Blackfan anemia through induction of miR-26a

Diamond–Blackfan anemia (DBA) results from haploinsufficiency of ribosomal protein subunits in hematopoietic progenitors in the earliest stages of committed erythropoiesis. Nemo-like kinase (NLK) is chronically hyperactivated in committed erythroid progenitors and precursors in multiple human and murine models of DBA. Inhibition of NLK activity and suppression of NLK expression both improve erythr

An Aspergillus nidulans GH26 endo-β-mannanase with a novel degradation pattern on highly substituted galactomannans.

Measurements of Large-Scale Parameters of a Distributed MIMO Antenna System in a Microcell Environment at 2.6 GHz

β-Mannanase BoMan26B from Bacteroides ovatus produces mannan-oligosaccharides with prebiotic potential from galactomannan and softwood β-mannans

Complex Involvement of Interleukin-26 in Bacterial Lung Infection

RIFM fragrance ingredient safety assessment, 2,6-nonadienenitrile, CAS Registry Number 67019-89-0

Life's Essential 8 and Life's Simple 7 in Relation to Coronary Atherosclerosis : Results From the Population-Based SCAPIS Project

TLR4-mediated release of heparin-binding protein in human airways : a co-stimulatory role for IL-26

Boosting of enzymatic softwood saccharification by fungal GH5 and GH26 endomannanases