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A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in mice

Acetaminophen (APAP) overdoses are of major clinical concern. Growing evidence underlines a pathogenic contribution of sterile postinjury inflammation in APAP-induced acute liver injury (APAP-ALI) and justifies development of anti-inflammatory therapies with therapeutic efficacy beyond the therapeutic window of the only current treatment option, N-acetylcysteine (NAC). The inflammatory mediator, h

Assessing the viability of probiotic preparations with flow cytometry. A comparison of different methods

Ändrade levnadsvanor i västerländska länder har lett till en ökning av sjukdomar så som IBS, infektioner i mag- och tarmkanal och allergier. Det har dessutom observerats att mikrofloran förändrats och goda bakterier så som Limosilactobacillus reuteri försvunnit. Mag- och tarmkanalen har därmed förlorat sina goda soldater mot patogena fiender med dysfunktionell balans som resultat. Därför är det inThis master thesis work was performed in collaboration with BioGaia AB, a Swedish biotech- company producing probiotic supplements containing the bacteria Limosilactobacillus reuteri. The products provided by BioGaia contain live microorganisms. Therefore, a method suitable for the correct enumeration of living cells is crucial in probiotic samples and today the so-called plate count method is use

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1 The Grammar of the Possession Link: Modern Hebrew yeS Constructions: Nora Boneh, Universit de Paris III Possessive constructions across languages make use either of HAVE or BE as the possession link. With the first, the possessor surfaces with Nominative case while the possessum bears Accusative case, with the second the possessor receives Dative case from the preposition accompanying BE, and th

https://konferens.ht.lu.se/fileadmin/user_upload/sol/ovrigt/konferens_console9_2000/Abstracts/Boneh.pdf - 2026-06-06

Development and validation of a machine learning-based model to predict isolated post-challenge hyperglycemia in middle-aged and elder adults : Analysis from a multicentric study

Introduction: Due to the high cost and complexity, the oral glucose tolerance test is not adopted as the screening method for identifying diabetes patients, which leads to the misdiagnosis of patients with isolated post-challenge hyperglycemia (IPH), that is., patients with normal fasting plasma glucose (<7.0 mmoL/L) and abnormal 2-h postprandial blood glucose (≥11.1 mmoL/L). We aimed to develop a

Mode of Coreceptor Use by R5 HIV Type 1 Correlates with Disease Stage: A Study of Paired Plasma and Cerebrospinal Fluid Isolates.

Abstract Through the use of chimeric CXCR4/CCR5 receptors we have previously shown that CCR5-tropic (R5) HIV-1 isolates acquire a more flexible receptor use over time, and that this links to a reduced viral susceptibility to inhibition by the CCR5 ligand RANTES. These findings may have relevance with regards to the efficacy of antiretroviral compounds that target CCR5/virus interactions. Compartme

Plural values of nature in emerging biodiversity credit markets: a case study of local values in Zimbabwean reforestation sites

Global biodiversity loss threatens ecological stability and human well-being. Biodiversity credits(biocredits) have emerged to address the funding gap for conservation, but may overlook local values and uses of nature, which are vital for sustaining cultural identities, livelihoods, and long-term stewardship of ecosystems. This thesis, grounded in the Plural Valuation of Nature framework, explores

Staden som en kollektiv aktör En abduktiv fallstudie på Malmö stad

Abstract Cities are once again becoming the locus of economic, social and political processes. The effect of these processes on the city is two-fold: one one hand they threaten to fragment and dislocate the city and the actors within them, on the other hand they give actors within cities new opportunities to react and mobilize resources towards different strategies of integration. The latter give

Previous dissertations

 2025-05-28 Veronica Fransson Improvements in brain imaging using spectral computed tomography: Development and evaluation of novel techniquesLÄS MER: https://lup.lub.lu.se/record/e8978f05-343b-4fa6-abac-be14c0f347ae 2025-05-09 Minna LernerMRI-based radiotherapy of brain tumours: Implementing MRI-only radiotherapy and exploring diffusion MRI for response assessmentLÄS MER: https://lup.lub.lu.se/re

https://www.msf-malmo.lu.se/dissertations/previous-dissertations - 2026-06-05

September 3rd 2020

From the Management The fall semester has begun and the students are (at least virtually) here – thank you everyone who is struggling with adapting the education to the ongoing situation!   There are no new guidelines regarding activities at the University, but it is still crucial that we all follow the Swedish Public Health Agency’s recommendations for reducing the spread of the covid 19-infectio

https://www.cec.lu.se/staff-pages/staff-newsletters/september-3rd-2020 - 2026-06-05