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Risk Factors for Valvulopathy Among Childhood Cancer Survivors

Importance Substantial improvements in childhood cancer survival have created a critical need to address serious long-term health complications, such as valvular heart disease (VHD). Objective To identify treatment-related risk factors for VHD in a large European cohort of long-term childhood cancer survivors. Design, Setting, and Participants This nested case-control study used data from the PanC

High-resolution postmortem 7 tesla MRI yields localized atrophy measures that are more sensitive to tau pathology and neuronal loss in Alzheimer’s disease than corresponding measures on antemortem 3 tesla MRI

BACKGROUND: Postmortem MRI has opened-up avenues to study brain structure at ultra high-resolution revealing details not possible to observe with in vivo MRI. Here, we present a novel package (purple-mri) which performs tissue segmentation, anatomical parcellation and spatial normalization of postmortem MRI. Additionally, we provide a framework to perform point-wise surface-based group-level studi

Native T1-mapping using cardiovascular magnetic resonance detects myocardium at risk during the first week following myocardial infarction in a swine model and in patients - comparison to contrast-enhanced cine steady-state free precession

Background: Myocardium at risk (MaR) can be evaluated by cardiovascular magnetic resonance (CMR) imaging using contrast-enhanced steady state free precession (CE-SSFP) in patients after ST-elevation myocardial infarction (STEMI). However, CE-SSFP utilizes gadolinium contrast, which is contraindicated in patients with severe renal insufficiency. Native T1-mapping is a non-contrast CMR method which

Mvec12schema v4

Schema Riskanalys inom natur, miljö och hälsa MVEC12 15 högskolepoäng, HT 2015 version 20150826 VECKA DATUM DAG TID TITEL Form Lärare Läs SAL HUS BLOCK V. 36 31-aug må 10-11 Upprop, Kursintroduktion S MH MOSSEN ÖSTER Ekologihuset INTRODUKTION KURS 01-sep ti 9-12 Introduktion om biomarkörer och hälsostudier F CL+ML 2 MOSSEN ÖSTER Ekologihuset HÄLSA 13-15 Risker med bekämpningsmedel i Sverige/Costa

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mvec12schema_v4.pdf - 2026-05-25

Mven16 ht16 28okt16 final

SchemaMVEN16_HT16_20okt16 SCHEMA 2016-10-28 Schema för MVEN16: Klimatpolitik, samhällsstyrning och kommunikation, 15 hp, HT 16 Kurstid: 2016-10-31 – 2017-01-15 Kursansvarig: Roger Hildingsson, roger.hildingsson@svet.lu.se Introduktion: 2016-10-31, kl. 11.00 (OBS! Uppropet startar prick kl. 11.00!) Lärare: CD: Carl Dalhammar, IIIEE, carl.dalhammar@iiiee.lu.se JAO: Johanna Alkan Olsson, CEC, johanna

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven16_ht16_28okt16_final.pdf - 2026-05-25

Schema mven12 v4

Lokalbokningslista Preliminärt schema 12 okt 2015 MVEN12 ht 2015 1 Preliminärt schema för MVEN12, 15 hp Kurstid: 2015-11-02 - 2016-01-15 Kursansvarig: Eva Jonsson, eva.jonsson@food.lth.se Introduktion: Mån 2 nov 2015, Ekologihuset, kl 10.00 Lärare: BJ Bjarne Johansson, Sydvatten AB, bjarne.johansson@sydvatten.se CH Charlott Håkansson, Inst livsmedelsteknik, LTH. charlott.hakansson@food.lth.se DJ D

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_mven12_v4.pdf - 2026-05-25

In-depth studies on sex trafficking in women: the case of justice response, jurisprudence and human rights in Southeastern Europe

Sex trafficking has from six hundred thousand to four million victims each year (McCabe and Manian, 2010: 41-43). Because of different legal barriers, sex trafficking is closely associated with organized crime; crime victims often do not search for support from legal systems, law enforcement authorities, or other officials (ibid.) This thesis was to understand how law affects the ability of preven

Breast cancer incidence, by stage at diagnosis, and mortality in 21 European countries in the era of mammography screening: an international population-based study

Background: Mammography screening programmes have been widely implemented across European countries over the past 40 years with the main aim to detect breast cancer earlier and thereby reduce breast cancer mortality. This study aimed to analyse and compare changes over time in breast cancer incidence, by stage at diagnosis, and breast cancer mortality across countries in relation to the timing of

Dual energy CT and deep learning for an automated volumetric segmentation of the major intracranial tissues : Feasibility and initial findings

Background: Magnetic resonance imaging (MRI) has traditionally been preferred over computed tomography (CT) for segmentation of intracranial structures due to its superior low contrast resolution. However, a reliable CT-based segmentation could improve patient management when MRI is not practical. Despite advancements in CT imaging, such as enhanced tissue differentiation using virtual monoenerget

Prenatal exposure to per- and polyfluoroalkyl substances (PFAS) and incidence of asthma and wheeze in childhood : A register-based cohort study in Ronneby, Sweden

BACKGROUND: Early-life exposure to per- and polyfluoroalkyl substances (PFAS) may impact the developing lungs and immune system and increase the risk of childhood asthma, but no studies have been conducted in a high-exposed population. The objective of this study was to estimate associations between prenatal PFAS exposure and childhood incidence of asthma and wheeze in Blekinge County, Sweden, whe

Decressac et al. pnas 2013

pnas201305623 1..10 TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity Mickael Decressaca,1, Bengt Mattssona, Pia Weikopb, Martin Lundblada, Johan Jakobssona, and Anders Björklunda,1 aDepartment of Experimental Medical Sciences, Wallenberg Neuroscience Center, Lund University, 22184 Lund, Sweden; and bLaboratory of Neuropsychiatry, Rigshospitalet University Hospita

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/decressac_et_al._pnas_2013.pdf - 2026-05-25

Impact of Human Papillomavirus (HPV)-6/11/16/18 Vaccine on All HPV-Associated Genital Diseases in Young Women.

Background The impact of the prophylactic vaccine against human papillomavirus (HPV) types 6, 11, 16, and 18 (HPV6/11/16/18) on all HPV-associated genital disease was investigated in a population that approximates sexually naive women in that they were "negative to 14 HPV types" and in a mixed population of HPV-exposed and -unexposed women (intention-to-treat group). Methods This analysis studied

Assessment of conventional cardiovascular risk factors and multiple biomarkers for the prediction of incident heart failure and atrial fibrillation.

OBJECTIVES: the purpose of this study was to assess the predictive accuracy of conventional cardiovascular risk factors for incident heart failure and atrial fibrillation, and the added benefit of multiple biomarkers reflecting diverse pathophysiological pathways. BACKGROUND: heart failure and atrial fibrillation are interrelated cardiac diseases associated with substantial morbidity and mortality

A preanalytic validation study of automated bone scan index : Effect on accuracy and reproducibility due to the procedural variabilities in bone scan image acquisition

The effect of the procedural variability in image acquisition on the quantitative assessment of bone scan is unknown. Here, we have developed and performed preanalytical studies to assess the impact of the variability in scanning speed and in vendor-specific γ-camera on reproducibility and accuracy of the automated bone scan index (BSI). Methods: Two separate preanalytical studies were performed:

Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest - an analysis of the TTM trial data

Background: Targeted temperature management is recommended after out-of-hospital cardiac arrest and may be achieved using a variety of cooling devices. This study was conducted to explore the performance and outcomes for intravascular versus surface devices for targeted temperature management after out-of-hospital cardiac arrest. Method: A retrospective analysis of data from the Targeted Temperatu

Getting the picture of home lighting: Adding participant photography to the interview

This paper draws attention to the potential benefits of using photographs in combination with interviews, that is to say photo elicitation. As defined by Harper (2002), photo elicitation is “based on the simple idea of inserting a photograph into a research interview” (p. 13). The photographs can be taken by the researcher or the participant to evoke comments. If participants are asked to produce

Downregulation of growth hormone in postural orthostatic tachycardia syndrome: insights from the SYSTEMA cohort

Background Postural orthostatic tachycardia syndrome (POTS) is a variant of cardiovascular autonomic disorder occurring predominantly in young women. POTS is characterized by an excessive heart rate increase when assuming upright posture accompanied by symptoms of orthostatic intolerance. The pathophysiology of POTS has not been fully established and is believed to be multifactorial. Purpose We a

CYP27A1 expression is associated with risk of late lethal estrogen receptor-positive breast cancer in postmenopausal patients

Background: 27-Hydroxycholesterol (27HC) stimulates estrogen receptor-positive (ER+) breast cancer (BC) progression. Inhibiting the sterol 27-hydroxylase (CYP27A1) abrogates these growth-promoting effects of 27HC in mice. However, the significance of CYP27A1 expression on BC biology and prognosis is unclear. Methods: Intratumoral CYP27A1 expression in invasive BC was measured by immunohistochemist