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Immune functions in melanoma patients during treatment with interferon [HuIFN-alpha (Le)] alone or in combination with cimetidine

While leukocyte interferon was found therapeutically ineffective in a series of 20 patients with metastatic malignant melanoma, subsequent combination treatment with interferon and cimetidine induced 5 complete and 1 partial tumour remissions. Prior to interferon therapy initiation, regressor patients demonstrated a significantly greater ability to mediate antibody-dependent cellular cytotoxicity

LES of pilot n-heptane ignition and its interaction with the lean premixed methane–air mixture in a dual-fuel combustion engine

Large eddy simulations of pilot fuel ignited, lean premixed, natural gas engines are performed to study the pilot-ignition process and its subsequent interaction with the premixed charge. The injection pressure (Pinj) and injection duration (Δinj) are varied (i.e. 800 bar/760μs, 800 bar/500μs, and 400bar/760μs) to study the impact of the injection process on the subsequent combustion evolution. Op

“Les copains *Dit au revoir” : On Subject–Verb Agreement in L2 French and Cross-Linguistic Influence

This study focuses on the production of subject–verb (SV) agreement in number in L2 French and investigates the role of cross-linguistic influence (CLI) in this particular morphosyntactic domain. CLI is a well-known phenomenon in Second Language Acquisition (SLA) research but it has rarely been investigated systematically in relation to SV agreement in French. The participants of the study are 114

SUSY Les Houches accord: interfacing SUSY spectrum calculators, decay packages, and event generators

An accord specifying a unique set of conventions for supersymmetric extensions of the Standard Model together with generic file structures for 1) supersymmetric model specifications and input parameters, 2) electroweak scale supersymmetric mass and coupling spectra, and 3) decay tables is presented, to provide a universal interface between spectrum calculation programs, decay packages, and high en

Mixing in wall-jets in a heavy-duty diesel engine : A les study

The paper presents a large eddy simulation investigation on the effect of fuel injection pressure on mixing, in an optical heavy-duty diesel engine. Recent investigation on impinging wall jets at constant-volume and quiescent conditions exhibited augmented air entrainment in wall jets with increasing injection pressure, when compared with a free jet. The increased mixing rates were explained as ow