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Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that
Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3
In the present study, two types of micro-pin–fin configurations were fabricated on silicon surfaces by a dry etching method, i.e., staggered pin fins (#1) and aligned pin fins with empty areas (#2). The micro-pin–fin surfaces were then further modified by depositing FeMn oxide nanoparticles (∼35 nm) electrostatically for 8 h and 16 h, respectively, namely #1-8h, #1-16h, #2-8h and #2-16h. Subcooled
Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi
Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe
How do we describe a location on earth? How do we describe a location on Earth? Geodetic reference system http://www.google.co.uk/imgres?imgurl=http://4.bp.blogspot.com/-v2sej--Hf9Y/TbGzN0FeN7I/AAAAAAAAAQ0/dXTA6XAP7Nk/s1600/earth-3d.gif&imgrefurl=http://ods-destruction-carbon-credits.blogspot.com/2011/04/happy-earth-day-from-remtec.html&usg=__1-2G0CU8X0-43x3j7NY4oN1vYS8=&h=1024&w=1024&sz=266&hl=en
https://www.nateko.lu.se/sites/nateko.lu.se/files/field2.pdf - 2026-07-16
Styr-/projektgrupp Peer support projektet inom Userinvolve – projektgruppsmöte! URBAN MARKSTRÖM (PI) ELISABETH ARGENTZELL ULRIKA BEJERHOLM PATRIK ENGDAHL ANNELI GUSTAVSSON, DAVID ROSENBERG Urban Markström (PI Userinvolve), professor, Umeå universitet Elisabeth Argentzell (PI Peer support), lektor, Lunds universitet, RS Ulrika Bejerholm, professor, Lunds universitet, Fou RS Patrik Engdahl, post doc
https://www.cepi.lu.se/sites/cepi.lu.se/files/2023-11/Peer%20Support%20Patrik%20Engdahl.pdf - 2026-07-16
Over the last few years, there has been a proliferation of different kinds of movements across the globe as citizens agitate for economic, socio-political and environmental change. In the Democratic Republic of Congo (DRC), where the country has been involved in a series of wars, attention has rather been eschewed towards the rape and sexual violence of women and girls. Using post-colonialism and
dmrr2427 557..567 Methods, quality control and specimen management in an international multicentre investigation of type 1 diabetes: TEDDY Kendra Vehik1* Steven W. Fiske1 Chad A. Logan1 Daniel Agardh2 Corrado M. Cilio2 William Hagopian3 Olli Simell4 Merja Roivainen5 Jin-Xiong She6 Thomas Briese7 Sami Oikarinen8 Heikki Hyoty8,9 Anette-G. Ziegler10 Marian Rewers11 Ake Lernmark2 Beena Akolkar12 Jeffr
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/27%2006032016_679_27_Vehik_DMRR_2013.pdf - 2026-07-16
© The Author(s) 2021. Published by Oxford University Press on behalf of the Guarantors of Brain. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. 1 Distinct subcellular aut
Professor Contact details Email: leif [dot] lonnblad [at] fysik [dot] lu [dot] se Phone: +46 46 222 77 80Organisation Particle and nuclear physics Visiting address: Sölvegatan 14A, Lund Room number: K233 Service point: 14 WebpageLeif Lönnblads profile in Lund University research portalResearchQCD Phenomenology and Monte Carlo Event Generators.TeachingTheoretical Particle Physics (FYTN18) and (Expl
https://www.particle-nuclear.lu.se/leif-lonnblad - 2026-07-15
Distinct cognitive effects and underlying transcriptome changes upon inhibition of individual miRNAs in hippocampal neurons 1Scientific Reports | 6:19879 | DOI: 10.1038/srep19879 www.nature.com/scientificreports Distinct cognitive effects and underlying transcriptome changes upon inhibition of individual miRNAs in hippocampal neurons Josephine Malmevik, Rebecca Petri, Pina Knauff, Per Ludvik Bratt
https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/publication_in_sci_rep_0.pdf - 2026-07-16
Background: In a previous study, we explored real-world programmed death-ligand 1 (PD-L1) testing and treatment patterns for patients with advanced non-small cell lung cancer (NSCLC) in the era of immune-oncology. The present study aimed to investigate overall survival (OS) with PD-(L)1 inhibitors with longer-term follow-up in the Swedish setting. Materials and methods: Data were extracted from th
Research Interests Contact details Email: david [dot] harper [at] mgeo [dot] lu [dot] seOrganisation Department of Earth and Environmental Sciences (MGeo) Service point: 16 WebpageDavid Harpers profile in Lund University research portalMy long-term research aims are focussed on the understanding of the origination and early evolution of animal-based ecosystems, their impact and relationships to cl
https://www.geology.lu.se/david-harper - 2026-07-15
Kursguide - Course Syllabus Books Anderson, Bridget (2015). Us and Them? The Dangerous Politics of Immigration Control. Oxford: OUP. 224 pages. ISBN: 978-0-198-73761-2 Betts, Alexander (Ed) (2012). Global Migration Governance. Oxford University Press. 368 pages, selected chapters. ISBN: 978-0-199-65380-5 Brettell, Caroline B. & James F. Hollifeld (2015). Migration Theory: Talking Across Discipline
https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/sims26_english_litteratur_16010_h16.pdf - 2026-07-16
