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Background. Anti-glomerular basement membrane (anti-GBM) disease often results in end-stage renal failure despite therapy with plasma exchange and immunosuppressive drugs. The newly discovered streptococcal enzymes IgG-degrading enzyme of S.pyogenes (IdeS) and endoglycosidase S (EndoS) act with remarkable specificity on circulating IgG. In this study, we investigate their ability in vivo to preven

The function of cultured mast cells may depend on genetic or environmental influence on the stem cell donor. This study investigates whether asthma or atopy in the donor influenced the growth and sensitivity of mast cells cultured from patients with asthma and healthy controls under identical conditions. Mast cells were cultured from peripheral blood from twelve patients with an objectively confir

In the study presented in this paper, the effect of different vehicle driving cycles on the pneumatic hybrid has been investigated. The pneumatic hybrid powertrain has been modeled in UT-Power and validated against experimental data. The GT-Power engine model has been linked with a MATLAB/simulink vehicle model. The engine in question is a single-cylinder Scania D12 diesel engine, which has been c

Soils beneath former dry cleaning sites are often contaminated with the chlorinated hydrocarbons PCE and its degradation products, which are highly toxic and cancerogenic. In this study, resistivity and time domain induced polarization (DCIP) were measured at a former dry cleaning site in order to investigate if the source contamination of PCE could be detected. 80 meter long 2D-profiles were meas

Examensarbetets titel: Bland Kulturvetare, Småpåvar och Heliga kor: en Kvalitativ Fallstudie om Organisatoriska Värderingars Dynamik och Tvetydighet Seminariedatum: 2017-06-01 Ämne/kurs: FEKH49, Examensarbete i organisation på kandidatnivå, 15 högskolepoäng Författare: Jimmy Björklund, Andreas Jansson och Adrian Schmidt Handledare: Devrim Göktepe-Hultén Nyckelord: Organisatoriska Värderingar, OrgaTitle: Among Cultural Know-it-alls, Micro-popes and Sacred cows: A Qualitative Case Study of the Dynamics and Ambiguity of Organizational Values Seminar date: 2017-06-01 Course: FEKH49, Bachelor Degree Project in Organization Undergraduate level, 15 University Credit Points Authors: Jimmy Björklund, Andreas Jansson and Adrian Schmidt Advisor: Devrim Göktepe-Hultén Keywords: Organizational Values,

Capitulation is wisdom - not defeat! The aim of this study has been an attempt to clarify how parents of children with neuropsychiatric disabilities such as autism, Down syndrome and intellectual disability manage to cope in their everyday life despite the high levels of stress and long term strain it involves being a parent and a caretaker of such a child. We focused our study on the family as a

This work presents a rapid, selective and sensitive automated sequential injection flow system with a capacitive biosensor for detection of the mecA gene (the model chosen for this study), which emerges from methicillin-resistant Staphylococcus aureus. A DNA-based 25-mer capture probe was immobilized on the surface of a gold electrode which was integrated in the capacitive sensor system. A constan

Ultrafast extreme-ultraviolet (XUV) and X-ray sources are revolutionizing our ability to follow femtosecond processes with ångström-scale resolution. The next frontier is to simultaneously control the direction, duration and timing of such radiation. Here, we demonstrate a fully functional opto-optical modulator for XUV light, similar to modulators available at infrared (IR) and visible wavelength

In research on Birka strong focus has since long been directed towards long-distance contacts with Western as well with and Northeastern Europe (todays Russia, Belarus and Ukraine). The great attention paid to west- and east European contacts has likely contributed to that contacts with Finland have fallen out of the discussions. However as seen from studies of the pottery in Birka the Baltic Finn

In the current work, cationic polymers functionalized with N-alicyclic quaternary ammonium (QA) cations were synthesized and characterized as potential hydroxide exchange membranes (HEMs) for application in fuel cells. Three different polymers, namely poly(arylene ether sulfone), spiro-ionene and poly(arylene alkylene), were explored as polymer backbones for the HEMs. Various mono- and spirocyclic

The feasibility of different options to reduce the risks of climate change has engaged scholars for decades. Yet there is no agreement on how to define and assess feasibility. We define feasible as “do-able under realistic assumptions.” A sound feasibility assessment is based on causal reasoning; enables comparison of feasibility across climate options, contexts, and implementation levels; and ref

Group A streptococcus (GAS) is a highly adapted, human-specific pathogen that is known to manipulate the immune system through various mechanisms. GAS’ M protein constitutes a primary target of the immune system due to its spatial configuration and dominance on the bacterial surface. Antibody responses targeting the M protein have been shown to favor the conserved C region. Such antibodies (Abs) c