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This study reconstructs the regional vegetation and climate dynamics between the upper Late Pleistoceneand Holocene around Pian del Lago, a coastal mountain marshland located at 831 m asl in westernLiguria (NW-Italy), based on the pollen analysis of a 13 m-long sediment core. The record provided aunique opportunity to study a poorly documented period in northern Italy and across many parts ofsouth
Aims: The aim of this study was to estimate the healthcare costs and productivity losses associated with county-based home-care services (HCS) for sick children. Methods: In this observational follow-up study, a combination of hospital care and HCS was compared to estimated alternative care solely at the hospital. Data on one year of healthcare utilisation for 32 children, supplied by the hospital
Nature-based adaptation planning is a challenging endeavor, not least because it requires transdisciplinary approaches to unite different actors' efforts and capacities. However, empirical knowledge on associated governance processes is scarce and fragmented. Against this background, this paper examines the integration of nature-based approaches for climate change adaptation into municipalities’ d
Problem Statement: Sandvik Rock Processing is in the need for a classification tool, which can help them improve their inventory management. Currently, there are problems with inefficiencies with deficit as well as excess in inventory. The new classification shall the basis for the differentiation of service levels and facilitate a shared view on items’ importance. Purpose: The purpose of this th
Freshwater blooms of the microcystin-producing (toxigenic) cyanobacterium Microcystis may cause severe damage to human health and the environment. However, toxigenic and non-toxigenic strains co-exist within single blooms, and microcystin concentration in the water varies throughout the season. We hypothesized that strains that produce and do not produce microcystins represent different genotypes.
Industry 4.0, with its focus on flexibility and customizability, is pushing in the direction of wireless communication in future smart factories, in particular, massive multiple-input-multiple-output (MIMO) and its future evolution of large intelligent surfaces (LIS), which provide more reliable channel quality than previous technologies. At the same time, network slicing in 5G and beyond systems
The dramatic increase in demand for wireless Internet access has lead to the introduction of new wireless architectures and systems including 3G, Wi-Fi and WiMAX. 3G systems such as UMTS and CDMA2000 are leaning towards an all-IP architecture for transporting IP multimedia services, mainly due to its scalability and promising capability of inter-working heterogeneous wireless access networks. Duri
In most genres of fiction representations of a profession, discipline or calling must broadly resonate with the conceptions of that role held by audiences. But very few represenations of PR practice to be found in novels written by UK-based writers draw a picture of PR activity that sits comfortably with the ”idealised” models offered by organisations such as the Chartered Institute of Public Re
Research on human emotions towards large carnivores is often based on self-reported emotions. This study aimed to investigate physiological and behavioral responses to feared animals among people who say that they are fearful or not fearful of brown bear and wolf. Participants were recruited to be bear fearful only (n=8), fearful of both bear and wolves (n=15), or fearful of neither carnivore (n=1
The enzyme ferrochelatase (EC 4.99.1.1) is the terminal enzyme in the biosynthetic pathway of heme b and catalyzes the insertion of Fe(II) into protoporphyrin IX. In this dissertation ferrochelatase from Bacillus subtilis was studied. A new purification method via inclusion bodies was developed that enabled simple purification of recombinant enzyme without tags or modifications that might affect t
N-Acetylneuraminic acid (Neu5Ac) is the most common form of sialic acid, a nine-carbon sugar often situated at the ends of glycoconjugates. Its unique reactivity makes it a complex substrate to work on, but new methods are continuously developed. In 2007, Ye et.al. reported a regioselective substitution by morpholine on position 4 of fully acetylated Neu5Ac, with retained stereochemistry. The anom
Achilles tendon rupture is becoming more prevalent with an increasing population of middle aged people participating in recreational sports. A torn Achilles tendon will likely not regain its original function, and it is unknown what treatment options are optimal. The Achilles tendon structure and how the tendon heals after a rupture varies between humans. A potentially useful tool in understanding
Background: Nutrition and lifestyle have been long established as risk factors for colorectal cancer (CRC). Modifiable lifestyle behaviours bear potential to minimize long-term CRC risk; however, translation of lifestyle information into individualized CRC risk assessment has not been implemented. Lifestyle-based risk models may aid the identification of high-risk individuals, guide referral to sc
Biogenic volatile organic compounds (VOCs) play important roles in atmospheric chemistry, yet most studies have focused on canopy emissions. Decomposition of forest litter, a major below-canopy VOC source, can substantially influence atmospheric oxidation and aerosol formation. Scots pine (Pinus sylvestris L.), one of the most widely distributed tree species across the boreal zone, produces terpen
Objective Type I interferons (IFN) drive systemic lupus erythematosus (SLE) pathogenesis. Some patients develop neutralizing IFN autoantibodies (anti-IFN ab), which theoretically could modify disease activity. We aimed to determine the prevalence of anti-IFN ab in patients with SLE, identify the age and when during the disease course of anti-IFN ab emerge, and assess their association with organ d
Relaxed eddy accumulation (REA) measurements for 14CO2 enable the estimation of fossil fuel (ff) CO2 fluxes in urban areas. This work is based on 252 REA ffCO2 flux measurements conducted on tall towers in the cities of Zurich, Paris, and Munich. The ffCO2 fluxes were compared to net eddy covariance CO2 fluxes to quantify the role of non-fossil (nf) CO2 fluxes. While the measurements in Zurich and
Very few countries have managed to decouple economic growth from resource use and greenhouse gas emissions in absolute terms and at rates to meet the climate targets of the Paris Agreement. To achieve this, technological solutions would need to be combined with sufficiency-oriented policies in a postgrowth context. This paper develops policy ideas for a sustainable welfare–work nexus via citizen e
The 2018–2019 Central European drought was probably the most extreme in Germany since the early sixteenth century. We assess the multiple consequences of the drought for natural systems, the economy and human health in the German part of the Elbe River basin, an area of 97,175 km2 including the cities of Berlin and Hamburg and contributing about 18% to the German GDP. We employ meteorological, hyd
Climate change affects the functioning of all of the components of food systems, often in ways that exacerbate existing predicaments and inequalities among regions of the world and groups in society. At the same time, food systems are a major cause of climate change, accounting for a third of all greenhouse gas (GHG) emissions. Therefore, food systems can and should play a much bigger role in clim
