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Background: Recruitment is one of the most serious challenges in performing randomized controlled trials. Often clinical trials with participants diagnosed with schizophrenia are terminated prematurely because of recruitment challenges resulting in a considerable waste of resources in the form of time, funding, and the participants' efforts. Dropout rates in schizophrenia trials are also high. Rec

During the last century (1900s) industrialized forms of agriculture and human activities have caused eutrophication of Baltic Sea waters. As a consequence, the hypoxic zone in the Baltic Sea has increased, especially during the last 50 years, and has caused severe ecosystem disturbance. Climate forcing has been proposed to be responsible for the reported trends in hypoxia (< 2 mg/l O-2) both durin

Leaf area index (LAI), a measure of canopy density, is a key variable for modelling and understanding primary productivity, and also water use and energy exchange in forest ecosystems. However, LAI varies considerably with phenology and disturbance patterns, so alternative approaches to quantifying stand-level processes should be considered. The carbon isotope composition of soil organic matter (C

We present quantitative reconstructions of regional vegetation cover in north-western Europe, western Europe north of the Alps, and eastern Europe for five time windows in the Holocene [around 6k, 3k, 0.5k, 0.2k, and 0.05k calendar years before present (bp)] at a 1 degrees x1 degrees spatial scale with the objective of producing vegetation descriptions suitable for climate modelling. The REVEALS m

In hybrid zones populations that are otherwise allopatric meet and produce hybrids. One of the most well-known hybrid zones occurs throughout much of Europe between the hooded and carrion crows. Even though these species (or subspecies) of crows look very different, genetic differentiation is weak, and introgression seems to be common. In a spatial simulation that was based on empirically estimate

The ‘BOADICEA’ Web Application (BWA) used to assess breast cancer risk, is currently being further developed, to integrate additional genetic and non-genetic factors. We surveyed clinicians’ perceived acceptability of the existing BWA v3. An online survey was conducted through the BOADICEA website, and the British, Dutch, French and Swedish genetics societies. Cross-sectional data from 443 partici

OBJECTIVE: Current radiation therapy capacities in Serbia and most of Eastern Europe are heavily lagging behind population needs. The primary study aim was assessment of direct costs of cancer medical care for patients suffering from cancer with assigned radiotherapy-based treatment protocols. Identification of key cost drivers and trends during 2010-2013 comparing brachytherapy and teleradiothera

The majority of research in second language acquisition has traditionally focused on classroom-based, instructed learning. However, with the spread of new technologies and the concomitant globalisation of popular culture, informal second language practices (ISLPs; e.g. watching films and television, using social media, or playing video games in another language) are increasingly becoming part of t

Modes of climate variability affect global and regional climates on different spatio-temporal scales, and they have important impacts on human activities and ecosystems. As these modes are a useful tool for simplifying the understanding of the climate system, it is crucial that we gain improved knowledge of their long-term past evolution and interactions over time to contextualise their present an

Background: Salinity is a significant environmental stress factor limiting crops productivity. Barley (Hordeum vulgare L.) has a natural tolerance to salinity stress, making it an interesting study object in stress biology research. In the present study, for the first time the effect of salinity stress on barley inflorescence developmental stages was investigated. Five spring barley genotypes irri

Fires have influenced atmospheric composition and climate since the rise of vascular plants, and satellite data have shown the overall global extent of fires. Our knowledge of historic fire emissions has progressively improved over the past decades due mostly to the development of new proxies and the improvement of fire models. Currently, there is a suite of proxies including sedimentary charcoal

Background Additional to a child's genetic inheritance, environmental exposures are associated with schizophrenia. Many are broadly described as childhood adversity; modelling the combined impact of these is complex. We aimed to develop and validate a scale on childhood adversity, independent of genetic and other environmental liabilities, for use in schizophrenia risk analysis models, using data

Objective To describe the incidence and burden of illness at the Tokyo 2020 Paralympic Games, which was organised with strict COVID-19 countermeasures. Methods Daily illnesses were recorded via the web-based injury and illness surveillance system (teams with their own medical staff; n=81), and local polyclinic services (teams without their own medical staff; n=81). Illness proportion, incidence an

Enligt Newsecs rapport från 2016 söker företag idag kontor som har effektiv kontorsyta med stor flexibilitet vad det gäller både area och hyresavtal. Deras analys är att sådana kontor kommer fortsätta att efterfrågas. Vad som menas med flexibla hyresavtal är inget som är självklart i branschen men i detta examensarbete innebär sådana hyresavtal kortare hyrestider och mindre ytor för varje aktör soAccording to Newsec's report from 2016 companies are looking for offices that have efficient office space with great flexibility in terms of both area and lease. Their analysis is that such offices will continue to be demanded. What is meant by flexible real estate leases is nothing that is obvious in the industry but in this paper such leases mean less lease times and less space for each part

Den termiska klimatupplevelsen påverkas mest av lufttemperaturen som är enkel att mäta med en vanlig termometer, men för att ta reda på hur temperaturen i ett rum upplevs räcker det inte med att enbart undersöka lufttemperaturen. Även om lufttemperaturen ligger på en komfortabel nivå så kan en kall yta i närheten få personen att känna att det är kyligt i rummet och på motsvarande sätt kan varma ytThe thermal climate experience is most affected by air temperature that is easy to measure with a standard thermometer, but to find out how the temperature in a room is felt it is not enough to merely examine the air temperature. Even if the air temperature is at a comforta-ble level, then a cold surface near get the person to feel that it is chilly in the room and cor-respondingly the hot surface

Hållbarhetsfrågor tar stort fokus i dagens debatter, personliga livsstilar samt företagens marknadsföring och affärsmodeller. Miljöarbetet i byggsektorn drivs framåt via bland annat miljöcertifieringssystem. Framförallt nybyggnation präglas idag starkt av skärpta miljölagkrav och miljöcertifieringar tillämpas här i stor utsträckning. Vikten av miljöarbetet med redan befintliga byggnader hamnar oftThe subject sustainability is taking a great amount of spotlight in most debates of modern society. This time the focus is on business models and marketing as well as the influences that sustainable certification systems have within the building sector. Especially when constructing new buildings, the new and stricter sustainability laws and certifications are setting the foundations of a new era.

A ubiquitous and accurate positioning system for mobile devices is of great importance both to business and research due to the large number of applications and services it enables. In most outdoor environments this problem was solved by the introduction of the Global Positioning System (GPS). In indoor or suburban areas however, the GPS signals are often too weak to enable a reliable position est

Today’s modern societies are becoming increasingly dependent on the vital societal functions that technical critical infrastructures provide, for example availability of electricity, tap water and internet connectivity. Hence, it is of essence that these infrastructures are resilient to interruptions. The purpose of this thesis is to investigate and contrast resilience levels of different types of

Earlier the regional social insurance office was exposed to critisism because of bad administration and a lack of providing public service. Among other things the regional social insurance office was attacked because of long investigation hours and indinstinct working methods and was blamed for not being able to solve the unhealth in the society. This lead to the reformation of the previous region