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Mutations in the TP53 tumor suppressor gene have been shown to significantly correlate with poor prognosis in endometrial cancer. In the present study we have evaluated a luminometric immunoassay (LIA) for quantitative estimation of TP53 protein expression in 65 cytosol preparations from endometrial cancer, previously analyzed for mutations in TP53 exons 4-10. LIA showed high (greater than or equa

Context Adjuvant imatinib administered for 12 months after surgery has improved recurrence-free survival (RFS) of patients with operable gastrointestinal stromal tumor (GIST) compared with placebo. Objective To investigate the role of imatinib administration duration as adjuvant treatment of patients who have a high estimated risk for GIST recurrence after surgery. Design, Setting, and Patients Pa

Spring phenophases such as the beginning of leaf unfolding, measured in the Irish gardens of the International Phenological Garden (IPG) network, indicate an earlier spring occurrence hence a longer growing season. However, these measurements are limited to selected species of trees at a few point locations in the southern half of the country. The aim of this study was to develop a methodology, ba

Popular Abstract in Swedish En värld av mikrober Vi lever i en värld full av olika bakterier och svampar, så kallade mikrober. Med tanke på artrikedomen och mängden av infektiösa mikrober vi dagligen kommer i kontakt med kan det nästan tyckas som ett smärre mirakel att vi trots allt är så friska som vi är. Detta är dock nästan helt och hållet vårt medfödda immunförsvars förtjänst. Immunförsvaret Abstract The epidermis is one of our primary interfaces towards the external milieu. Following injury, the physical barrier function of the skin is destroyed and the epidermis is left vulnerable to microbial invasion. Inducible innate immune response mechanisms exist to keep the wound site free from infection, thus allowing the wound to heal and the epidermis to re-establish its barrier function.

Popular Abstract in Swedish En experimentell och teoretisk studie kring bränder i varulager i både modell och verklig skala har genomförts. Teoretiska modeller för att beräkna flamhöjder, gas temperaturer, gas hastigheter och värmeflöde inuti spalterna mellan de lagrade varorna presenteras. Modellerna kan t ex användas för att beräkna tid till utlösning av olika sprinklers som används för att skydA theoretical and experimental study of rack storage fires and responsiveness of sprinklers is presented. Free-burn tests with non-combustible and combustible material were carried out in reduced scale with verification in large scale. Formulas for in-rack flame height, excess gas temperature, gas velocity and heat flux to storage walls are provided. The formulas include overall heat release rate,

Background. The development of fluid and salt retention is a potential problem for all peritoneal dialysis (PD) patients. Sodium removal by the peritoneum is predominantly determined by convective fluid loss but influenced by diffusion and sieving due to free water transport as predicted by the three-pore model (TPM). The aim of the study was to establish the effect of transport status, dwell leng

Background. T-cell lymphoblastic lymphoma (T-LBL) is a rare neoplasm of precursor lymphoblast origin, for which there is no standard treatment for adults. Results of current treatment strategies in selected populations do exist but are largely unreported for unselected series. Here, we aimed to investigate treatment outcome in a population-based cohort. Material and methods. Patients were identifi

The notion of organizations as learning entities has gained considerably in popularity over the last decade, and is now regarded an important issue both theoretically and in practice. Many organizational activities and events have been referred to as learning phenomena, and learning theory is being applied to increasingly varied and complex settings of organizational life. This divergence would su

Popular Abstract in Swedish Avhandlingen består av fem upsatser (A-E): I uppsats A undersöks tidsberoende egenskaper hos kölängdsprocessen hos ett kösystem med flera betjänter under mycket allmänna Markovska ankomstprocesser. I uppsats B undersöks en endimensionell slumpvandring som reflekteras i två barriärer. I uppsats C undersöks ruinsannolikheten i en Cramér-Lundberg-modell där utbetalningaThis thesis consists of five papers (A-E). In Paper A, we study transient properties of the queue length process in various queueing settings. We focus on computing the mean and the Laplace transform of the time required for the queue length starting at $x

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Plastikkirurgi och rekonstruktiv kirurgi syftar till att återskapa form och funktion i kroppens yttre vävnader, efter större defekter orsakade av t.ex. trafikolyckor, brännskador eller tumöroperationer. Sedan länge har man använt förflyttning av hud (hudtransplantat) och rotation eller förflyttning av större vävnadsområden med bibehålMicrovascular surgery enables free tissue flaps to cover tissue defects, e.g. after trauma and malignancies. Although major improvements in techniques have been made, problems with poor tissue circulation and thrombus formation still exist. The aim of this thesis was to investigate the effects of hemodilution on tissue blood flow and thrombus formation in an animal model. In isovolemic hemodilutio

Purpose EURAMOS-1, an international randomized controlled trial, investigated maintenance therapy with pegylated interferon alfa-2b (IFN-α-2b) in patients whose osteosarcoma showed good histologic response (good response) to induction chemotherapy. Patients and Methods At diagnosis, patients age ≤ 40 years with resectable high-grade osteosarcoma were registered. Eligibility after surgery for good

BACKGROUND: Sabellarids, also known as honeycomb or sandcastle worms, when building their tubes, produce chemical signals (free fatty acids) that are responsible for larval settlement and the formation of three-dimensional aggregations. The larval palps and the dorsal hump (becoming the median organ in adults) are presumed to participate in such a substrate selection during settlement. Notably, th

Secondary AML (s-AML), including AML with an antecedent hematologic disorder (AHD-AML) and therapy-related AML (t-AML), constitutes a large proportion of patients with AML and is considered to confer a dismal prognosis. The role of allogeneic hematopoietic cell transplantation (HCT) in patients with s-AML and the extent to which HCT is performed in these patients has been little studied to date. W

Bradykinin receptors have been identified in human gingival fibroblasts; the primary signal transduction pathways and their dependence on calcium have been characterized. Binding data revealed a calcium-independent binding of bradykinin to the cell membrane with a receptor density of 25,000 receptors per cell and a K d of 1.6 nM. The bradykinin receptor-mediated activation of phospholipase C (PLC

GÅS Nyhetsbrev för året 2018 Nyhetsbrev 2018 till dig som deltar i ett världsunikt projekt 102-åringen som varit med sedan det började Det är sjätte gången som Ingrid kommer till GÅS- projektets mottagning i Malmö, och hon har nu hunnit fylla 102 år. Hon har varit med sedan forsk- ningsprojektet började och tycker att det har varit in- tressant att få vara med och hjälpa till med forskning, särski

https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/nyhetsbrev2018_fin_tg_0.pdf - 2026-05-23

Tyrens_5_nov_2013_Malmö Avfallsförebyggande i EU:s direktiv Hervé Corvellec Institution för Service Management och tjänstevetens kap Lunds Universitet & GRI, Göteborgs universitet HUT Skåne - Nätverk för avfallsförebyggande Malmö, 5 november 2013. 1. Vad är avfall? Etymologi • Avfall : av + fall (cf Abfall på tyska ) • Déchets : dé (markera en separation) + choir (gammal franska för att falla ) •

https://www.ses.lu.se/sites/ses.lu.se/files/hut_5_nov_2013_malmoe.pdf - 2026-05-23

Syfte: Syftet med detta examensarbete är att undersöka hur mogna företagets inköpsavdelningar är och om mognadsgrad har något samband mellan hur de arbetar och mäter sin inköpsfunktion, samt att undersöka hur stora företag jobbar med indirekt inköp idag. Problembeskrivning: De olika frågorna som studien önskar besvara kan sammanfattas enligt följande: * Var befinner sig företagens mognadsgrad enlPurpose: The purpose of this master's thesis is to examine how companies work with performance measurements for purchasing of indirect materials and services and its relation to purchasing maturity. Problem formulation: These are the five research questions for this study: * How developed are the companies purchasing departments? * How are the companies working with indirect purchasing? * Wha

Background: Recent knowledge in animals suggests that gut microbial metabolism may affect host metabolism, including appetite regulating hormones. The aim of the present study was to evaluate the potential effects of a whole grain barley kernel product, rich in intrinsic indigestible carbohydrates (dietary fibre and resistant starch), on markers of metabolism and appetite regulation in healthy sub

Popular Abstract in Swedish Avhandlingen består av en introduktion och följande artiklar: Artikel I: Using resultants for SAGBI basis verification in the univariate polynomial ring. Författare: Anna Torstensson, Victor Ufnarovski och Hans Öfverbeck. Sammanfattning: En resultant-identitet för polynom i en variabel bevisas och används för att karakterisera SAGBI-baser för underalgebror genereradeThe thesis consists of an introduction and the following four papers: Paper I: Using resultants for SAGBI basis verification in the univariate polynomial ring. Authors: Anna Torstensson, Victor Ufnarovski and Hans Öfverbeck. Abstract: A resultant-type identity for univariate polynomials is proved and used to characterise SAGBI bases of subalgebras generated by two polynomials. A new equivalent

What is known and objective: Interventions involving medication reconciliation and review by clinical pharmacists can reduce drug-related problems and improve therapeutic outcomes. The objective of this study was to examine the impact of routine admission medication reconciliation and inpatient medication review on emergency department (ED) revisits after discharge. Secondary outcomes included the