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Cohort profile : Bladder Cancer Data Base Sweden (BladderBaSe) 2.0

PURPOSE: We constructed Bladder Cancer Data Base Sweden (BladderBaSe) 2.0 to expand studies in BladderBaSe on incidence, treatment outcomes, side effects, survival and health economic aspects of men and women with cancer in the urinary bladder, upper tract urothelial carcinoma (UTUC) (renal pelvis and ureter) and urethral carcinoma. PARTICIPANTS: BladderBaSe 2.0 includes 53 298 patients with cance

Association of circulating let-7b-5p with major depressive disorder : a nested case-control study

BACKGROUND: Major depressive disorder (MDD) is one of the most common psychiatric disorders and is a great disease burden. However, its underlying pathophysiology and aetiology remain poorly understood. Available evidence suggests that circulating microRNAs (miRNAs) are associated with MDD, but it is still unknown whether miRNAs can predict subsequent incident MDD.METHODS: In this nested case-cont

Effects of red blood cells with reduced deformability on cerebral blood flow and vascular water transport: measurements in rats using time-resolved pulsed arterial spin labelling at 9.4 T

BackgroundOur aim was to introduce damaged red blood cells (RBCs) as a tool for haemodynamic provocation in rats, hypothesised to cause decreased cerebral blood flow (CBF) and prolonged water capillary transfer time (CTT), and to investigate whether expected changes in CBF could be observed and if haemodynamic alterations were reflected by the CTT metric.MethodsDamaged RBCs exhibiting a mildly red

A Composite Risk Score for Capsule Complications Based on Data from the Swedish National Cataract Register : Relation to Surgery Volumes

Purpose: To investigate case mix in relation to capsule complication, possible associations between case mix and operation volume, and change in case mix over time. Design: Register-based study. Participants: Swedish patients who underwent cataract surgery between 2007 and 2016. Methods: Demographics and data on ocular comorbidity, intraoperative difficulties, and capsule complications were regist

Sex as predictor for achieved health outcomes and received care in ischemic stroke and intracerebral hemorrhage : A register-based study

Background: Differences in stroke care and health outcomes between men and women are debated. The objective of this study was to explore the relationship between patients' sex and post-stroke health outcomes and received care in a Swedish setting. Methods: Patients with a registered diagnosis of acute intracerebral hemorrhage (ICH) or ischemic stroke (IS) within regional administrative systems (IC

Increased Gun Violence Among Young Males in Sweden : a Descriptive National Survey and International Comparison

This population-based time-trend study examines gun violence rates among males in Sweden during the years 1996 to 2015 and compares the rate in Sweden to other Western European countries. Data were collected from six registries and are presented descriptively per 100,000 inhabitants. The risks among males in Sweden increased considerably in both lethal and non-lethal gun victimization and perpetra

An Experimental Study of Heterostructure Tunnel FET Nanowire Arrays : Digital and Analog Figures of Merit from 300K to 10K

In this work, we experimentally report the figures of merit of state-of-the-art heterostructure Tunnel Field-Effect-Transistor (TFET) arrays from room (300K) down to cryogenic temperature (10K) at supply voltages below 400mV. We demonstrate here, for the first time, that InAs/InGaAsSb/GaSb Nanowire (NW) TFETs are robust enough to maintain excellent figures of merit over a large temperature range

Global biogeography of fungal and bacterial biomass carbon in topsoil

Bacteria and fungi, representing two major soil microorganism groups, play an important role in global nutrient biogeochemistry. Biogeographic patterns of bacterial and fungal biomass are of fundamental importance for mechanistically understanding nutrient cycling. We synthesized 1323 data points of phospholipid fatty acid-derived fungal biomass C (FBC), bacterial biomass C (BBC), and fungi:bacter

Validation of the Skåne University Hospital nomogram for the preoperative prediction of a disease-free axilla in patients with breast cancer

BACKGROUND: Axillary staging via sentinel lymph node biopsy (SLNB) is performed for clinically node-negative (N0) breast cancer patients. The Skåne University Hospital (SUS) nomogram was developed to assess the possibility of omitting SLNB for patients with a low risk of nodal metastasis. Area under the receiver operating characteristic curve (AUC) was 0.74. The aim was to validate the SUS nomogra

Utilization of psychiatric services prior to suicide- a retrospective comparison of users with and without previous suicide attempts

INTRODUCTION: The aim was to investigate psychiatric health care utilization two years before death by suicide among individuals with previous suicide attempts (PSA) compared with those without (NSA).METHOD: A retrospective population-based cohort study was conducted including 484 individuals who died by suicide in Sweden in 2015 and were in contact with psychiatric services within the two years p

Relative importance of climatic variables, soil properties and plant traits to spatial variability in net CO2 exchange across global forests and grasslands

Compared to the well-known drivers of spatial variability in gross primary productivity (GPP), the relative importance of climatic variables, soil properties and plant traits to the spatial variability in net ecosystem exchange of CO2 between terrestrial ecosystem and atmosphere (NEE) is poorly understood. We used principal component regression to analyze data from 147 eddy flux sites to disentang

Neurochemical profile of the developing mouse cortex determined by in vivo 1H NMR spectroscopy at 14.1 T and the effect of recurrent anaesthesia

The neurochemical profile of the cortex develops in a region and time specific manner, which can be distorted by psychiatric and other neurological pathologies. Pre-clinical studies often involve experimental mouse models. In this study, we determined the neurochemical profile of C57BL/6 mice in a longitudinal study design to provide a reference frame for the normal developing mouse cortex. Using

Hand Mobility in Scleroderma (HAMIS) test: the reliability of a novel hand function test.

Objective Hand Mobility in Scleroderma (HAMIS) is a new hand function test developed for adults who have systemic sclerosis. HAMIS consists of 9 items designed to measure all movements assessed in an ordinary range of motion (ROM)-measured hand test. The aim of this study was to examine the reliability of the test. Methods Two observers (one occupational therapist and one physiotherapist) perform

Exhaustion measured by the SF-36 vitality scale is associated with a flattened diurnal cortisol profile.

The possible association between stress-related exhaustion and reduced activity in the hypothalamo-pituitary-adrenal (HPA) axis is increasingly in focus. The aim of the present study was to examine whether exhaustion measured in a non-patient population is associated with alterations in diurnal cortisol profile. The study population included 78 working individuals. The study group was dichotomised

Effects of complex information presentation on change decision making

The result of using a Common Point of Reference framework decision base, to implement implicit information patterns, aimed to support business decisions during the initial phases of change and improvement projects, was examined in this study. Participants (n=30) were asked to solve four different assignments with a decision base as support consisting of fictive change project data from a fictive m

Are GARCH Models Appropriate for Analysing Volatility Structures in Fundamental Valuations of the OMXS30?

This thesis investigates the volatility structures found in forward-looking fundamental valuations of the Swedish stock index OMXS30. The evaluated data constitutes daily observations of P/E ratios based on twelve months earnings estimates during the period 2009-01-02 until 2018-10-18. The analysis is conducted by applying a GARCH modelling framework to a log-return transformed return series deriv

Ämnesord, redundans, nationalbibliografi : ämnesordens redundans i nationalbibliografin

There is an ongoing discussion in information retrieval research regarding the merits of subject indexing with controlled vocabularies as opposed to relying on free-text descriptions. Earlier research has compared subject headings with other metadata, such as document titles or tables of contents, to determine the relative value of subject headings as subject access points in an information search

Kommuners tillsyn av rökfria skolgårdar- En innehållsanalys av kommuners inspektionsrapporter

Kommuners tillsyn av rökfria skolgårdar Rökning kostar det svenska samhället uppskattat 30 miljarder kronor per år i kostnaden för sjukvård, produktionsförluster och sjukskrivning. Rökning bland ungdomar har minskat de senaste åren, men det är fortfarande nästan en fjärdedel av alla elever i årskurs 2 på gymnasiet, ser sig själv som rökare. För att stoppa ungdomar från att röka genomför kommunen The purpose of this study was to investigate the supervision of non-smoking school yards in Sweden. Smoking costs Swedish society an estimated 30 billion SEK annually in cost for healthcare, production losses and sick leave. Smoking among adolescents has declined in recent years, but it is still 24 % in high school's grade 2, which categorized as smokers. The supervision of the schoolyard is t

Dags för domaren att komma in i matchen? En analys av domstolens ansvar för utredningen i brottmål

Framställningen behandlar domstolens ansvar för utredningen i brottmål och problematiken kring de skillnader som har uppstått mellan regleringen i rättegångsbalken och praxis bland domare. Enligt rättegångsbalken har domstolen tilldelats ett visst ansvar för att målet blir tillräckligt utrett. Bestämmelserna i rättegångsbalken har många år på nacken och härrör från en tid då åklagarväsendet inte vThis essay deals with the court’s responsibility for the investigation in connection to criminal cases, as well as the problems regarding the differences that have appeared between the regulation in rättegångsbalken (the Swedish criminal procedural act) and practice amongst judges. According to rättegångsbalken, the court has, to some degree, a responsibility to assure that the case is properly