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BACKGROUND.: We conducted this prospective longitudinal multicenter study to evaluate the health-related quality of life (HRQL) of patients with oral carcinoma at diagnosis, and after 1 and 5 years in relation to tumour location and treatment modality. METHODS.: One hundred twenty-two patients (mean age, 61; 62% males) with oral carcinoma were evaluated with standardized HRQL questionnaires, the E
Background Mental health interventions should demonstrate an effect on patients' functioning as well as his/her needs, in particular on unmet needs whose assessment depends on the perspective of either the patient or the clinician. However, individual met and unmet needs appear to change over time, qualitatively and quantitatively, raising questions about their sensitivity to change and about the
Patch-clamp recordings and glucagon release measurements were combined to determine the role of plasma membrane ATP-sensitive K+ channels (K-ATP channels) in the control of glucagon secretion from mouse pancreatic alpha-cells. In wild-type mouse islets, glucose produced a concentration-dependent (half-maximal inhibitory concentration [IC50] = 2.5 mmol/l) reduction of glucagon release. Maximum inhi
All service control nodes, for example Web sites or Mobile Switching Centers, can be modeled as server systems with one or more servers processing the incoming requests. To avoid overload at the service control node different types of admission control mechanisms are usually implemented. In this paper we discuss, from a control point of view, the modeling of a service control-node. The queue is as
There is a need for mathematical modelling for the evaluation of important parameters for photon imaging systems. A Monte Carlo program which simulates medical imaging nuclear detectors has been developed. Different materials can be chosen for the detector, a cover and a phantom. Cylindrical, spherical, rectangular and more complex phantom and source shapes can be simulated. Photoelectric, incoher
Dalteparin, a low molecular weight heparin (LMWH), is given to pregnant women with thrombotic disorders. Clinical observations together with the documented changes of heparan sulfate proteoglycans in normal and protracted labor fostered the idea that LMWH shortens delivery time. Labor time was retrospectively determined among nulliparous pregnant women treated with dalteparin because of previous v
Oat-based beverages enriched with vitamins and minerals were produced with common hydrothermal treatments and stored at 22 degrees C for 64 weeks. The effects of decanting on the retention of native vitamins, minerals and fatty acids, and different UHT holding time (5 s or 20 s) at 140 degrees C on vitamins were investigated. Fatty acid profile, vitamin retention and dissolved oxygen concentration
Many product-based companies have identified digital services as a promising way to differentiate themselves and to stimulate future growth. However, as digital services frequently induce a business model change to a pay-per-use or subscription model, companies see themselves increasingly challenged as their revenues are progressively dependent on customers’ actual usage. This is in contrast to th
I slutet av 90-talet utvecklades produkten korslimmat trä, KL-trä. Framtagningen av KL-trä var ett projekt för att framställa ett byggnadsmaterial med avseende att kunna konkurrera med betongindustrin och därigenom bidra till en lägre miljöpåverkan, då trä har en låg påverkan på miljön i förhållande till många andra konstruktionsmaterial. KL-träelement är vanligtvis konstruerade som plattor och haIn the late 1990s cross-laminated timber (CLT) was developed. The development of CLT was a project aimed to produce a structural product that could compete with the concrete industry and contribute to a reduced effect on the environment, due to the low environmental impact of timber in relation to other building materials. CLT elements are usually constructed as panels which contain multiple layer
Continuous Delivery (CD) has today become an essential part of software development for a reliable and automated quality assurance process. However, the challenge of introducing CD starts with setting up a CD pipeline and providing the necessary infrastructure for it, which may take a considerable amount of time and require expertise knowledge. This complex and costly implementation will also requ
The paleobiogeography of Early–Middle Devonian (Pragian–Eifelian) brachiopods from West Gondwana was assessed to determine any potential controls (regional climatic differences or global eustasy) that may have driven bioregionalization. The Pragian–Eifelian interval of West Gondwana was examined because work by previous authors suggested that this was a period when regionally extensive areas of pr
Self-service technology (SST) is implemented in-store as a way of facilitating and enhancing customer experience in which value is co-created. Previous research on SSTs has been mainly conducted in utilitarian settings where discussions were inclined towards attributes of value-in-use with an emphasis on efficiency. However, when implemented in a hedonic retail setting such as fast fashion, co-cre
The main goal of this project was to investigate how the thermal stability of two different types of polyhydroxyalkanoates; poly(3-hydroxybutyrate) and poly(3-hydroxybutyrate-co-4-hydroxybutyrate) were affected when washing them with acid solution. Initially, four different acids were used: citric acid, hydrochloric acid, formic acid and acetic acid. Citric acid gave the best results for both biop
Combustion of fuel in diesel engines emits substances harmful to the environment such as soot. These emissions can be reduced by either in-cylinder treatments or after-treatments. One of the common in-cylinder treatments is multiple-injection, which divides a single fuel injection to multiple smaller injections. There are many open questions on the physical processes of the ignition, combustion a
Low-lying states in the isotope Xe130 were populated in a Coulomb-excitation experiment performed at CERN's HIE-ISOLDE facility. The magnitudes and relative signs of seven E2 matrix elements and one M1 matrix element coupling five low-lying states in Xe130 were determined using the semiclassical coupled-channel Coulomb-excitation least-squares search code gosia. The diagonal E2 matrix elements of
OBJECTIVE: To investigate the association between long term residential exposure to road traffic and railway noise and risk of incident dementia.DESIGN: Nationwide prospective register based cohort study.SETTING: Denmark.PARTICIPANTS: 1 938 994 adults aged ≥60 years living in Denmark between 1 January 2004 and 31 December 2017.MAIN OUTCOME MEASURES: Incident cases of all cause dementia and dementi
Background and Objectives: With an ageing population, the number of older persons with substance use problems, particularly problematic alcohol use, is increasing. Despite growing recognition of the negative consequences of problematic alcohol use on older persons, there is a dearth of knowledge about the alcohol use profiles and the dimensionality of alcohol problems in older people. Moreover, l
Analysis of structures subjected to moving loads is presented. In particular, structural effects due to structure-vehicle interaction are studied. The basic equations of the structure-vehicle system are derived by means of continuum mechanics, the finite element method and multibody dynamics.In order to consider the interaction between structure and vehicle in a straightforward way, a special stru
The transglycosylation behavior and capacity of two clan GH-D α-galactosidases, BoGal36A from the gut bacterium Bacteroides ovatus and Aga27A from the guar plant, was investigated and compared. The enzymes were screened for the ability to use para-nitrophenyl-α-galactoside (pNP-Gal), raffinose and locust bean gum (LBG) galactomannan as glycosyl donors with the glycosyl acceptors methanol, propanol
