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The structure, biosynthesis, and metabolism of proteoglycans in the HL-60 human promyelocytes were studied by metabolic labeling in culture with [35S]sulfate, [3H]glucosamine, [3H]serine, and [3H]leucine. These cells synthesize a single predominant species of intracellular proteoglycan with an approximate molecular weight of 100,000. The cells contain about 1 μg of proteoglycan/million cells. The
The purpose, of this degree project, is to make a detailed analysis of how young consumers experience overconsumption as a phenomenon. We also aim to understand how overconsumption can be a part of the consumer’s identity making process. We have managed qualitative, interviews with eight respondents in the ages 20-30 years. The interviews have been semi-structured and based on dialogue, where the
The aim of this study was to find an understanding of elderly care staff´s views on documentation requirement and documentation as a task and also to examine managers views on implementation of new tasks. We wanted to enter more deeply into the tension between the managers´ expectations, based on the set of goals made from politicians, and the response of this from the elderly care staff and what
Today most companies have online sales channels. Most commonly have companies started offline and then later expanded online while others have started their business online through, for example, web shops. Even though we today are living in a high technology society, the existence of an offline sales channel is still needed. But what is the exact definition of a sales channel really? In today’s
Denna studie bygger på huvudfrågan: Har musiken i grundskolan någon påverkan på elevens inställning till musik senare i livet? Under studien har nya infallsvinklar tagit form och lett studien till resultatet: Musiklärarens påverkan. Från en relativt smal syn på musikundervisningen i grundskolan har element som t ex läroplaner och ledarskapsteorier vidgat studiens syn för vad musiklärare i grundsko
Previous in vitro studies have implied that the Wnt-5a gene plays a role as a tumor suppressor. To explore the clinical relevance of this concept, 96 primary invasive breast carcinomas were stained with a novel anti-Wnt-5a antibody. Loss of Wnt-5a protein expression, evident in 44% of the invasive ductal carcinomas (n = 59), was significantly associated with higher histological grade (P = 0.01) an
”Den som sa det han var det”. Ett klassiskt svenskt ordspråk företrädelsevis populärt bland barn att dra till med när argumentationen tagit slut i en hetsig diskussion. Men också en ypperlig titel på denna uppsats då den ger uttryck för en mycket vanlig uppfattning; den som erkänner brott måste också vara skyldig till detsamma. I Rättegångsbalken stadgas det att ett erkännande i brottmål endast tj"Den som sa det han var det." A classic Swedish saying, especially popular amongst children when found themselves run out of arguments in a heated discussion. But also an excellent title for this paper as it reflects a very common belief; the one who confesses a crime must also be guilty of the same. The Swedish law states that a confession in criminal cases only serve as evidence, which
Children should not be exposed to unwanted chemicals in their everyday life and several organizations in Sweden are working towards reducing the amount of chemicals that exists in toys and material intended for preschools. Many municipalities are joining the project, and are now working towards the goal “toxic free preschools”. In this struggle the municipalities have an impact in their procuremen
Naturliga metanutsläpp sker från våra våtmarker världen över. Metan produceras naturligt genom nedbrytning i de syrefria förhållanden som en våtmark erbjuder. För att bättre kunna modellera och skala upp hur mycker metan som faktiskt släpps ut från dessa våtmarker måste ytterligare förståelse skapas över varför metanutsläppen varierar så kraftigt både i tid och rum. Denna studie försöker öka förstMethane emissions from natural wetlands are an important contributor to methane levels in the atmosphere. These emissions are highly variable in time and space, even within sites. Further understanding of this variation is vital to successfully model the overall methane emissions from wetlands. This study investigates spatial variation through measurements of 22 plots across Fäjemyr bog. Manual me
Title: The Service Terminator – when people are being replaced by machines University: Lund University, Campus Helsingborg, Department of Service Management Course: SMKK01, Service Management, Bachelor’s degree, 15 hp, 2012 Seminar date: May 29, 2012 Authors: Sanna Axbom, Maria Ingstad, Emma Nilsson and Lina Sonesson Supervisors: Christian Fuentes and Rickard Ek Keywords: Self-service technologies
Popular Abstract in Swedish Aerob kapacitet, i dagligt tal konditionen, är den maximala förmågan att utföra ett fysiskt arbete karaktäriserat av den maximala syreförbrukningen (V'O2max). Detta maximala arbete kan endast utföras en begränsad tid, till stor del beroende på en tilltagande anaerob metabolism, vilken bl.a. avspeglas som en ökning av utvädrat CO2 i lungorna. Längre tids arbete kan emellDifferent methods are proposed to assess the aerobic capacity. A novel scale, rating of perceived capacity (RPC) based on metabolic equivalents (METs) from 1 to 20, is presented. Selected MET values are linked to physical activities. Comparison of the rating with an exercise test in a group of women revealed that a correction based on age more accurately predicted the maximal exercise capacity. An
Popular Abstract in Swedish Oberoende av om det är i ett samhälle, datornätverk eller organen i en mänsklig kropp, så är behovet av kommunikation stort i en komplex miljö. Eftersom den komplicerade människokroppen är beroende av kommunikation för att reglera funktioner, skickas otaliga mängder signaler oavbrutet. För att signalerna skall vara meningsfulla så måste de kunna tas emot och behandlas. Intercellular communication is of crucial importance in regulating physiology and G-protein coupled receptors (GPCRs) have evolved as an important mechanism in this process. Of the approximately 800 human GPCRs, about 160 are still considered to be “orphan” receptors for which an endogenous ligand remains to be identified. Since an estimated 50% of all clinical drugs act on 30 known GPCRs, the rem
This study reports thermodynamic and kinetic data of Sb(III) adsorption from single metal solutions onto synthetic aqueous goethite (α-FeOOH). Batch equilibrium sorption experiments were carried out at 25 °C over a Sb:Fe molar range of 0.005-0.05 and using a goethite concentration of 0.44 g Fe/L. Experimental data were successfully modelled using Langmuir (R2 ≥ 0.891) and Freundlich (R2 ≥ 0.990) i
The purpose was to study the prognostic and predictive roles of DNA protein kinase catalytic subunit (DNA-PKcs), Ku70/80 and p53 for the effect of radiotherapy in breast cancer patients. Protein expressions of Ku70/80, DNA-PKcs and p53 were examined using immunohistochemistry in tumours from 224 breast cancer patients, who were randomised to receive post-operative radiotherapy or adjuvant chemothe
The donor (BTR-Cl) and acceptor (BTP-FCl-FCl) have well-defined small molecule properties and excellent repeatability, and they can form charge transfer complexes with a wide spectral absorption range. Using density functional theory (DFT), we simulate the photoinduced charge transfer of bulk-heterojunction (BHJ) organic solar cell (OSC) materials modulated by the external electric field (Fext) at
Background: Little is known about the relative impact of the preoperative symptoms rest pain and tissue loss, and of the arterial segment revascularized, on amputation rate and mortality in patients with chronic limb-threatening ischemia (CLTI). We wanted to investigate this topic further. Method: This population-based observational cohort study involved 10 419 patients revascularized for CLTI in
Objectives: Treatment-free remission (TFR) has emerged as a treatment goal in chronic myeloid leukemia in the chronic phase (CML-CP). Attempts to increase proportion of patients achieving TFR include combination of tyrosine kinase inhibitors (TKI) and other drugs. Interferon-α in addition to TKI has shown promising efficacy but with dose-dependent toxicity and discontinuations. NordCML007 was init
During initiation of messenger RNA translation in bacteria, the GTPase initiation factor (IF) 2 plays major roles in the assembly of the preinitiation 30S complex and its docking to the 50S ribosomal subunit leading to the 70S initiation complex, ready to form the first peptide bond in a nascent protein. Rapid and accurate initiation of bacterial protein synthesis is driven by conformational chang
Type 1 diabetes is a chronic autoimmune disease requiring insulin treatment for survival. Prolonged duration of type 1 diabetes is associated with increased risk of microvascular complications. Although chronic hyperglycemia and diabetes duration have been considered as the major risk factors for vascular complications, this is not universally seen among all patients. Persons with long-term type 1
