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Oral treatment with a vitamin D3 analogue (BXL628) has anti-inflammatory effects in rodent model of interstitial cystitis

To investigate the effects of a vitamin D3 analogue (BXL628) in a model of chronic cystitis, as calcitriol analogues might be an interesting new therapeutic option for interstitial cystitis, for although the cause of the disease remains unclear, the increase in mast cells in the mucosa and detrusor muscle are significant. We devised a mouse model of allergen-induced allergic cystitis that is assoc

Antibody-dependent allostery of the M1 protein

Den förrädiska antikroppen Streptokocker är en lömsk bakterie som har många olika sätt att ta sig runt vårt immunförsvar. Den kan låtsas vara en del av vår kropp genom att klä sig själv i en proteinkapsel som är väldigt likt ett mänskligt protein, bryta ned våra celler med hjälp av utsöndrade gifter och använda vårt immunförsvar mot oss genom att binda antikroppar till sig själv. En virulensfaktoThe Group A streptococcus (GAS) (Streptococcus pyogenes) is a significant human pathogen known for causing a diverse range of diseases, spanning from mild diseases such as pharyngitis to life-threatening diseases such as necrotizing fasciitis. Its virulence comes from a plethora of immune evasion mechanisms, but the M protein with its hypervariable region and ability to bind human proteins, stands

Boka lokal och mötesrum

Lokaler, resurser, priser och konferenslokaler. På denna sida hittar du information om hur man bokar lokaler och resurser i bokningssystemet TimeEdit. LokalbokningFör att boka lokal loggar du in i bokningssystemet TimeEdit med ditt Lucat-ID. Observera att en beställd lokal är bokad först när du fått en bekräftelse per e-post.Boka lokal i TimeEditBefogenhet och konteringssträngDu behöver ha ekonomi

https://www.medarbetarwebben.lu.se/stod-och-verktyg/lokaler-och-parkering/boka-lokal-och-motesrum - 2026-05-17

In-Store Recycling - A Consumer Perspective

Syftet med uppsatsen är att studera hur ett segment av Generation Y ser på in-store recycling - en tjänst myntad av författarna till arbetet. In-store recycling är en tjänst som många fast fashion retail-bolag har börjat erbjuda genom att placera insamlingslådor för kläder som konsumenter vill ha återvunnet eller återanvänt, och i retur får konsumenten en belöning i form av en rabattkupong. För at

Follow-up of men with elevated prostate-specific antigen and one set of benign biopsies at prostate cancer screening

Objective: To study the follow-up of men with elevated prostate-specific antigen (PSA) (>3 ng/ml) after one benign set of sextant biopsies. From the Goteborg branch of the European Randomised Study of Screening for Prostate Cancer (ERSPC). Method: 456 men with one set of benign sextant biopsies were followed every second year for 4 years with PSA determinations. In cases of elevated PSA, transrect

Doxorubicin-melphalan with and without cisplatin in advanced ovarian cancer--ten-year survival results from a prospective randomized study by the Swedish Cooperative Ovarian Cancer Study Group

In a controlled prospective randomized study the regimen doxorubicin (A) 40 mg/m2 + melphalan (M) 0.4 mg/kg was compared with A + M + cisplatin (C) 50 mg/m2 given every four weeks in advanced ovarian cancer, FIGO stage III or IV and with serous or anaplastic histology. From 1981 to 1983, 300 patients entered the study and 295 patients were evaluable for response, toxicity and long-term survival. A

Polygenic pathways shape white matter vulnerability to Alzheimer’s disease-related pathophysiological changes

Background: The accumulation of amyloid-β1−42 (Aβ1−42) peptides and phosphorylated-Tau181 (p-Tau181) tangles from the preclinical stages of Alzheimer’s disease (AD) has led to a biological definition of the disease. However, among Aβ1−42-positive individuals, cognitive decline onset varies, and some never develop symptoms. Genetic influences on molecular pathways and their interactions with protei

Vt18 mven17 schema

MVEN17 Samhällsplanering med klimatperspektiv VT2018 Kurstid: 15 januari - 19 mars 2018 Kursansvarig: Johanna Alkan Olsson johanna.alkan_olsson@cec.lu.se Lärare LU: Helena Hanson Helena.hanson@cec.lu.se Nora Smedby nora.smedby@iiiee.lu.se Maria Johanson maria.johansson@arkitektur.lth.se Litteratur: Enligt separat lista Studieteknik: Läs om studieverkstaden Studenträttigheter: Läs om dina rättighet

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/vt18_mven17_schema.pdf - 2026-05-18

Snabblånemarknaden och konsumenten

Under 2006 introducerades snabblån på den svenska kreditmarknaden. Snabblån är ett mindre lån som betalas ut snabbare än traditionella lån och har oftast en kort återbetalningsperiod. Sedan 2006 har kritiska röster höjts mot låneformen. Snabblånen har präglats av godtyckliga kreditkontroller, höga räntor och fokusering på en redan utsatt konsumentgrupp. Låneformen har huvudsakligen kritiserats förHigh-cost credits were introduced on the Swedish credit market during 2006. High-cost loans are small loans that are paid out faster than traditional loans and usually have a shorter amount of time before payback is due. Since 2006, critics have raised their voices against this type of loan. High-cost loans have been characterized by deficient credit checks, high interest rates and a focus on an a

Bimodal solutions in peritoneal dialysis : what can we expect from different glucose volumes added to the icodextrin bag? Data from a simulation procedure

Background: Ultrafiltration (UF) insufficiency in peritoneal dialysis (PD) often leads to transfer to hemodialysis. Therefore, strategies to prolong time on therapy are needed. The use of a combined crystalloid and colloid solution, also called bimodal PD, can help improve UF. Methods: We propose a method for reconstituting bimodal solutions. Three bimodal PD solutions, with respectively 100 ml (s

Reconstructing institutional stability and change Conceptualizing the social ontology of institutional stability and change in Historical Institutionalism

Questions about institutional stability and change are critically important for any understanding of political institutions. The field of Historical institutionalism in political science has described, studied and theorized institutions for decades. One of the most recurring concepts utilized in the explanation of institutional stability is path dependence, describing theoretical and empirical mec

Technological systems and development blocks

Successful technological transitions require the alignment of technologies, capabilities, infrastructure, and institutions across a wide array of industries and involving many agents. In such processes, synergies and complementarities across different fields of economic activity are crucial. When such complementarities are missing, imbalances emerge, which, in the absence of innovation, may stifle

Mven03 preliminar planering schema ht 2020 v7

MVEN03 Ht 2020 MILJÖVETENSKAP Preliminär planering/schema 200823 Kurs: MVEN03 - Miljövetenskap: Analys och metodik, 15 hp HT 2020 Kursansvarig: Nina Reistad NR nina.reistad@fysik.lth.se Lärare: Charlotta Turner CT charlotta.turner@chem.lu.se Per Erik Isberg PEI per-erik.isberg@stat.lu.se Pål Axel Olsson PAO pal_axel.olsson@biol.lu.se Martijn van Praagh MVP martijn.van_praagh@mv.lu.se Björn Klatt B

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven03_preliminar_planering_schema_ht_2020_v7.pdf - 2026-05-18