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Group G streptococci mediate fibrinogendependent platelet aggregation leading to transient entrapment in platelet aggregates

Platelets have been reported to become activated in response to bacteria and this is proposed to contribute to the acute response to bacterial infection. In the present study, we investigated platelet aggregation in response to group G streptococci (GGS) in vitro in healthy human donors and in vivo in a mouse model of streptococcal sepsis. Platelet aggregation by GGS was dependent on the bacterial

Litteraturlista Bedömning Och Betygssättning Ht 21

Litteraturlista Bedömning och betygssättning Artiklar och böcker Carlgren, Ingrid., Forsberg, Eva., & Lindberg, Viveca. (2009). Perspektiv på den svenska skolans kunskapsdiskussion. (s. 11–39). Stockholms universitetsförlag. https://www.diva- portal.org/smash/get/diva2:371489/FULLTEXT01.pdf [ca 28 s.] Green, Jenny. (2018). Återkoppling för lärande och utveckling av undervisningen. Skolverket. http

https://www.mhm.lu.se/sites/mhm.lu.se/files/2021-06/Litteraturlista%20Bedo%CC%88mning%20och%20betygssa%CC%88ttning%20ht%2021.pdf - 2026-04-28

Combined protein A imprinting and cryogelation for production of spherical affinity material

Cryogels have been demonstrated to be efficient when applied for protein isolation. Owing to their macroporous structure, cryogels can also be used for treating particle-containing material, e.g. cell homogenates. Another challenging development in protein purification technology is the use of molecularly imprinted polymers (MIPs). These MIPs are robust and can be used repeatedly. The paper presen

Recent advances in the mechanisms and treatment of immune thrombocytopenia

Primary immune thrombocytopenia is an autoimmune disease associated with a reduced peripheral blood platelet count. The phenotype is variable with some patients suffering no bleeding whilst others have severe bleeding which may be fatal. Variability in clinical behaviour and treatment responses reflects its complex underlying pathophysiology. Historically the management has relied heavily on immun

Epitope specificity and isotype of monoclonal anti-D antibodies dictate their ability to inhibit phagocytosis of opsonized platelets

Rh immune globulin (WinRho SDF; Cangene, Mississauga, ON, Canada) is an effective treatment for autoimmune thrombocytopenic purpura; however, maintaining a sustained supply for its use in autoimmune thrombocytopenic purpura and its primary indication, hemolytic disease of the newborn, makes the development of alternative reagents desirable. We compared Rh immune globulin and 6 human monoclonal ant

Endoglycosidase treatment abrogates IgG arthritogenicity: Importance of IgG glycosylation in arthritis.

The glycosylation status of IgG has been implicated in the pathology of rheumatoid arthritis. Earlier, we reported the identification of a novel secreted endo-beta-N-acetylglucosaminidase (EndoS), secreted by Streptococcus pyogenes that specifically hydrolyzes the beta-1,4-di-N-acetylchitobiose core of the asparagine-linked glycan of human IgG. Here, we analyzed the arthritogenicity of EndoS-treat