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176 You Et Al. Predictors Of Transitions From GADA As The Initial Autoantibody To Multiple Autoantib

Predictors of Transitions From GADA as the Initial Autoantibody to Multiple Autoantibodies of Type 1 Diabetes in Children at Risk by a Dynamic Prediction Model - 10022025_679_176_MP280_You_Ped Diab_2025.pdf PdrdYpbg :pshbkd Mpdchbsnpr ne SpZmrhshnmr Dpnl F9C9 Zr sgd HmhshZk 9tsnZmshancw sn Ltkshokd 9tsnZmshanchdr ne Swod 0 ChZadsdr hm Bghkcpdm Zs Phri aw Z CwmZlhb Mpdchbshnm Lncdk Kt Wnt0 DZkZrshm

https://www.teddy.lu.se/sites/teddy.lu.se/files/2025-11/176%20You%20et%20al.%20Predictors%20of%20Transitions%20From%20GADA%20as%20the%20Initial%20Autoantibody%20to%20Multiple%20Autoantibodies%20of%20Type%201%20Diabetes%20in%20Children%20at%20Risk%20by%20a%20Dynamic%20Prediction%20Model%20-%20Ped%20Diab_2025.pdf - 2026-04-23

Digital rundtur i Lund

Vi har samlat ihop några av godbitarna från universitetets långa historia och skapat en rundtur som du kan gå med hjälp av din mobil. ”Lundarundan”, många stopp på litet områdeRundturen går genom gamla och nya Lund, med fokus på de södra centrala delarna av campusområdet. Du får lära dig om Lund, stadens och studenternas historia samt lära känna byggnader och nationer.Karta över rundturen i Google

https://www.lu.se/studera/valja-studier/traffa-oss/digital-rundtur-i-lund - 2026-04-24

Effects of chronic citalopram treatment on central and peripheral spontaneous open-field behaviours in rats

The spontaneous open-field behavioural effects of 10 days of chronic treatment with two clinical doses (10 and 20 mg/kg daily) and one high/toxic dose (100 mg/kg daily) of the selective serotonin reuptake inhibitor citalopram (delivered subcutaneously by implanted osmotic pumps) were examined in rats. Central and peripheral arena locomotor and rearing activities were recorded simultaneously, and t

Tissue response of radiation therapy assessed by electrical impedance spectroscopy (EIS) in subcutaneous tumours in rats.

Föreliggande undersökning syftar till att utvärdera möjligheten att använda bioimpedansspektrometri för att mäta tumör- och vävnadsrespons på strålterapi. Bioimpedansmätningar utförda med CythorLab ™ utrustade med en signalgenerator med en känd högutgångsimpedans och signalmätanordning som kan mäta spänningen som appliceras av generatorn. Styrenheten utlöser signalgeneratorn som genererar en MLS-sThe present investigation aims to evaluate the possibility of using bio-impedance spectrometry to measure tumour and tissue response to radiation therapy. Bio -impedance measurements performed with CythorLab™ equipped with a signal generator with a known high output impedance and signal measuring device able to measure the voltage applied by the generator. The control unit triggers the signal gene

Selection on the joint actions of pairs leads to divergent adaptation and coadaptation of care-giving parents during pre-hatching care

The joint actions of animals in partnerships or social groups evolve under both natural selection from the wider environment and social selection imposed by other members of the pair or group. We used experimental evolution to investigate how jointly expressed actions evolve upon exposure to a new environmental challenge. Our work focused on the evolution of carrion nest preparation by pairs of bu

A comparison of different orthogonal techniques for the investigation of the conformational stability of NIST mAb in liquid formulations

Antikroppar har ett brett användningsområde med stor potential men det är svårt att skapa stabila lösningar. Den strukturella stabiliteten är en viktig faktor när man väljer läkemedelskandidater, och i de tidiga utvecklingsstadierna görs prediktiva undersökningar för att ta reda på varje kandidats stabilitet och utvecklings-potential. Därmed är det av största intresse att utvärdera hur antikropparA great challenge during early development of medicinal antibodies is to determine the stability of the candidates. This is required to be able to select the candidates with the greatest developability. The stability of the candidates can be estimated using different orthogonal techniques and the aim of this investigation was thus to use orthogonal techniques for the investigation of conformationa

Rapid prediction of soil hydraulic and physicochemical properties using the Nix Pro color sensor

Color is the most obvious and easily determined soil property that can provide crucial information about soil composition. The NIX™ Pro color sensor (Nix) presents a user-friendly alternative to the traditional Munsell manual method, with reduced sensitivity to environmental and human factors. Therefore, a new method was developed to use Nix in combination with machine learning to quickly and affo

Inhibition of coxsackie B virus infection by soluble forms of its receptors: Binding affinities, altered particle formation, and competition with cellular receptors

We previously reported that soluble decay-accelerating factor (DAF) and coxsackievirus-adenovirus receptor (CAR) blocked coxsackievirus 133 (CVB3) myocarditis in mice, but only soluble CAR blocked CVB3-mediated pancreatitis. Here, we report that the in vitro mechanisms of viral inhibition by these soluble receptors also differ. Soluble DAF inhibited virus infection through the formation of reversi

Changes in resting-state functional connectivity after stroke in a mouse brain lacking extracellular matrix components

In the brain, focal ischemia results in a local region of cell death and disruption of both local and remote functional neuronal networks. Tissue reorganization following stroke can be limited by factors such as extracellular matrix (ECM) molecules that prevent neuronal growth and synaptic plasticity. The brain's ECM plays a crucial role in network formation, development, and regeneration of the c

ICOS-ligand triggering impairs osteoclast differentiation and function in vitro and in vivo

Osteoblasts, osteocytes, and osteoclasts (OCs) are involved in the bone production and resorption, which are crucial in bone homeostasis. OC hyperactivation plays a role in the exaggerated bone resorption of diseases such as osteoporosis, rheumatoid arthritis, and osteolytic tumor metastases. This work stems from the finding that OCs can express B7h (ICOS-Ligand), which is the ligand of the ICOS T

Systemic sclerosis. Novel molecular and epidemiological features of disease.

Popular Abstract in Swedish Systemisk skleros (SSc) är en relativt ovanlig reumatologisk sjukdom som kan engagera många av kroppens organ. Sjukdomen kallas ibland också för sklerodermi. Typiskt för sjukdomen är att huden omvandlas till fibros och blir hård och stram över olika delar av kroppen. Typiskt för sjukdomen är också att drabbade patienter har försämrad funktion i sina blodkärl, framförallSystemic sclerosis (SSc) is a systemic rheumatic disease with significant mortality and morbidity. Different estimations of disease prevalence and incidence have been presented from various parts of the world. While lung involvement is a common cause of SSc-related death, a majority of SSc patients suffer from symptoms originating in the gastrointestinal (GI) tract. By combining data from a popu