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Studies of bacterial surface proteins interacting with the immune system

Popular Abstract in Swedish En av de viktigaste substanserna i vår kropp är proteiner, också kallade äggviteämnen. Proteiner har en mängd olika uppgifter i kroppen, de finns i våra celler där de har olika uppgifter såsom att fungera som enzymer, transportörer, signalsubstanser, eller som skyddsfaktorer. Proteiner ingår också som viktiga beståndsdelar i vävnaderna mellan cellerna och finns dessutomPathogenic bacteria express a wide array of surface proteins that interact with the environment. Many of these proteins are believed to be important for the virulence. This thesis deals with the binding of immunoglobulins (Ig) and complement regulating proteins to certain bacterial surface proteins. Protein L from Peptostreptococcus magnus binds to Igk-light chains while protein A from Staphylococ

Circulating Human Basophils and Dendritic Cell Subsets. Aspects of antigen recognition and presentation in type I allergic immune responses

Popular Abstract in Swedish En tredjedel av befolkningen i världens industrialiserade länder lider av allergi, t.ex. allergisk rinit (hösnuva). Trots detta vet man relativt lite om de cellulära och molekylära mekanismer som ligger till grund för det immunologiska svaret vid allergi. Genom att studera dessa mekanismer kan man hitta sätt att angripa dem, vilket förhoppningsvis kan leda till bättre lAllergic diseases currently affect a third of the population in the industrialized parts of the world. Despite this, the cellular and molecular mechanisms involved in the induction and activation of allergic diseases are not fully clarified. Dendritic cells (DCs) link the innate and adaptive immunity and play vital roles in protective immunity against pathogens, as well as in inducing tolerance t

Local CTLA4 blockade effectively restrains experimental pancreatic adenocarcinoma growth in vivo.

Antibody-mediated blockade of CTLA4 has been shown to be effective in treating a select group of patients with late-stage melanoma. The precise mechanism underlying the clinical activity of CTLA4 immunotherapy is poorly understood, although recent experimental findings indicate that antibody-mediated depletion of regulatory T cells (Tregs) in the tumor microenvironment plays a key role in efficaci

Eosinophils in anti-neutrophil cytoplasmic antibody associated vasculitis

Background: Anti-neutrophil cytoplasmic antibodies associated vasculitides (AAV) are characterized by autoimmune small vessel inflammation. Eosinophils are multifunctional cells with both pro-inflammatory and immunoregulatory properties. Tissue activated eosinophils secrete cyto- and chemokines and form extracellular traps (EETs), they release free granules and produce reactive oxygen species. The

IL1RAP Blockade with a Monoclonal Antibody Reduces Cardiac Inflammation and Preserves Heart Function in Viral and Autoimmune Myocarditis

BACKGROUND: Currently, there are no therapies targeting specific pathogenic pathways in myocarditis. IL (interleukin)-1 blockade has shown promise in preclinical studies and case reports. We hypothesized that blockade of IL1RAP (IL-1 receptor accessory protein), a shared subunit of the IL-1, IL-33, and IL-36 receptors, could be more efficient than IL-1 blockade alone. METHODS: We induced coxsackie

Multitask Convolutional Neural Network Emulators for Global Crop Models - Supervised Deep Learning in Large Hypercubes of Non-IID Data

The aim of this thesis is to establish whether a neural network (NN) can be used for emulation of simulated global crop production - retrieved from the computationally demanding dynamic global vegetation model (DGVM) Lund-Potsdam-Jena General Ecosystem Simulator (LPJ-GUESS). It has been devoted to elaboration with various types of neural network architectures: Branched NNs capable of processing in

Psp 180912 nr6 protokoll mu

PROTO KOLL 6:2018 Dnr STYR 2018/1350 LUN DS UNIVERSITET Institutionen for psykologi ledningsgruppen for psykologprogrammet Sammantradesdatum 2018-09-12 Niirvarande ledamoter Martin Wolgast Kristian Almquist Maja Bengtsson Strath Bengt Brattgard Daiva Daukantaite Gorana Holm Maria Holmqvist Tomas Jungert Jens Knutsson Erik Lundin Berti( Persson Susanna Vestberg Margit Wangby Lundh Anita Lennerstedt

https://www.psy.lu.se/sites/psy.lu.se/files/psp_180912_nr6_protokoll_mu.pdf - 2026-05-06

MVES04 Schema 2021 210219

Nytt Schema Centrum för miljö- och klimatforskning, CEC, Miljövetenskaplig Utbildning, Sölvegatan 37, 223 62 Lund http://www.miljovetenskap.lu.se/ Preliminärt Schema MVES04 - Miljöövervakning, 15p VT21 Kurstid: 24 mars - 31 maj maj Kurschef: Adam Kristensson, tel:046-2227645, email: adam.kristensson@nuclear.lu.se Yann Clough, tel: 046-2226831, email: yann.clough@cec.lu.se Lärare: Namn Email AKR Ad

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/2021-02/MVES04_Schema%202021_210219.xlsx - 2026-05-05

GNVB10 HT21

Brevmall Postadress Box 117, 221 00 Lund, Besöksadress Allhelgona kyrkogata 14 M, Telefonväxeln 046-222 00 00 Webbadress http//:graduateschool.sam.lu.se Department o f Gender S tudies Litteraturlista GNVB10 Det jämlika vårdmötet, 7,5 hp Axelsson Fisk, S., Ekberg Jansson, A., Stridsman, C., & Merlo, J. (2021). Socioekonomiska riskfaktorer bör beaktas i kvalitetsregister. Lakartidningen, 6-7/2021. 2

https://www.genus.lu.se/sites/genus.lu.se/files/2021-06/GNVB10%20HT21.pdf - 2026-05-06

GNVB10-litteraturlista-HT22

GNVB10 Litteraturlista HT22 Postadress Box 117, 221 00 Lund, Besöksadress Allhelgona kyrkogata 18 C, Telefonväxeln 046-222 00 00 Webbadress https://www.genus.lu.se/ Genusvetenskapliga institutionen Litteraturlista GNVB10 Det jämlika vårdmötet, 7,5 hp Axelsson Fisk, S., Ekberg Jansson, A., Stridsman, C., & Merlo, J. (2021). Socioekonomiska riskfaktorer bör beaktas i kvalitetsregister. Lakartidninge

https://www.genus.lu.se/sites/genus.lu.se/files/2022-06/GNVB10-litteraturlista-HT22.pdf - 2026-05-06

Defining the Limits of Corporate Responsibilities against the Concept of Legal Positive Obligations

Defining the Limits of Corporate Responsibilities against the Concept of Legal Positive Obligations - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Edu

https://rwi.lu.se/publications/defining-the-limits-of-corporate-responsibilities-against-the-concept-of-legal-positive-obligations/ - 2026-05-05

The Migration Industry and the Commercialization of International Migration - The Raoul Wallenberg I

The Migration Industry and the Commercialization of International Migration - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice

https://rwi.lu.se/publications/the-migration-industry-and-the-commercialization-of-international-migration/ - 2026-05-05

JoL Handlingsplan 2024-2027-2

240919 Soc ia lhögskolan Socialhögskolans handlingsplan för jämställdhet och lika villkor 2024-2027 I föreliggande dokument beskrivs Socialhögskolans arbete med jämställdhet och lika villkor (JoL). Del 1 utgörs av handlingsplanen, dvs utgångspunkterna för institutionens JoL-arbete. Del 2 utgörs av planerade, pågående och avslutade åtgärder i enlighet med handlingsplanens målsättningar. JOL-arbetet

https://www.soch.lu.se/internt/sites/soch.lu.se.internt/files/2026-01/JoL%20Handlingsplan%202024-2027-2.pdf - 2026-05-06

Study of Gamma-ray Response of LaBr3:Ce Scintillation Detectors for an Iridium Coincidence Spectrometer

Vid avdelningen för kärnfysik utvecklas för närvarande andra generationens Ir-koincidensspektrometer. Anledningen till detta är att det finns ett stort behov bland geologer att mäta spårkvantiteter av Iridium i olika geologiska skikt för att korrelera skiktens ålder med eventuella stora meteoritnedslag. Första generationens spektrometer byggde på en dubbelkoincidens mätt med två HPGe-detektorer, mPresently, the development of the second generation Ir coincidence spectrometer is talking place at the division of Nuclear Physics. There is a large need among geologists to measure trace quantities of Ir in different geological layers and correlate the age of the layer with different large meteorite impacts. The first generation Ir spectrometer was based on a coincidence measured by two HPGe det

Studies on streptococcal M proteins. Interactions with IgA and human complement regulators

Popular Abstract in Swedish Streptococcus pyogenes (grupp A streptokocker) är en bakterie som orsakar flera olika infektionssjukdomar hos människan, av vilka de vanligaste är halsfluss och svinkoppor. För att kunna infektera sin värd använder sig en patogen bakterie av virulens-faktorer och S. pyogenes uttrycker flera olika sådana. Den viktigaste av dessa anses vara M proteinet som Streptococcus pyogenes (group A Streptococcus) expresses several different virulence factors. Of these, the M protein is regarded as one of the most important, because it confers resistance to phagocytosis, allowing the bacterium to multiply in blood. A remarkable property of M proteins is their ability to bind different human plasma proteins, in partic