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Surface based fluidics for particle sorting

We have created devices that are extremely simple to fabricate, function without pumps, are reusable and capable of dealing with very large differences in particle sizes without clogging. Our new approach to microfluidic particle sorting is precise enough for applications in blood fractionation, cancer cell sorting, parasite detection and sample decomplexing in general. We achieve this using Deter

Extraction of circulating tumor cells from blood using acoustophoresis

We present, for the first time, separation of three different prostate cancer cell lines from leukocyte fractions by means of continuous flow acoustophoresis. This flow-through separation approach, which utilize acoustophoretic forces to extract CTCs from blood has a significant advantage over affinity based methods in the sense that it comprises a non-contact and label free separation of CTCs fro

Vertical nanotubes connected by a subsurface nanochannel

We have built an array of vertical nanotubes connected by a subsurface nanofluidic channel. The nanotube system is to be used for cell injections. By culturing cells on top of the nanotubes the cells will be pierced and molecules can enter the cells via the subsurface channel. Several channels can be made on the same sample and different molecules can be injected into different subpopulations of c

Elimination of resistive losses in large-area LEDs by new diffusion-driven devices

High-power operation of conventional GaN-based light-emitting diodes (LEDs) is severely limited by current crowding, which increases the bias voltage of the LED, concentrates light emission close to the p-type contact edge, and aggravates the efficiency droop. Fabricating LEDs on thick n-GaN substrates alleviates current crowding but requires the use of expensive bulk GaN substrates and fairly lar

Traffic Management Algorithms in Differentiated Services Networks

The Differentiated Services (DiffServ) Architecture, a Quality of Service (QoS) solution being worked on by an IETF work group, is aimed to solve the increasing problems with no service guarantees in the current Internet. New services such as video-on-demand and IP-telephony will be unusable without some sort of service guarantees on which to build applications on. A replacement architecture for t

Density-based particle fractionation

We present a label-free method capable of rapidly sorting particles based on their densities. Our device relies on deterministic lateral displacement (DLD) and achieves density fractionation by the use of T-shaped posts. By combining it with a lateral density gradient we achieve a density separation that is independent of size within a range given by the device geometry. Herein we present a proof-

A lipid-based passivation scheme for nanofluidics

Stretching DNA in nanochannels allows for direct, visual studies of genomic DNA at the single molecule level. In order to facilitate the study of the interaction of linear DNA with proteins in nanochannels, we have implemented a highly effective passivation scheme based on lipid bilayers. We show long-term passivation of nanochannel surfaces to several relevant reagents and demonstrate that the pe

Separation of deformable hydrogel microparticles in deterministic lateral displacement devices

To better understand how deformable and non-spherical particles behave in sorting devices based on deterministic lateral displacement we generate models of biological particles with tunable size, shape and mechanical properties using stop-flow lithography and we explore how these parameters play a role in our separation devices. Hollow and solid cylinders are compared with respect to their deforma

A high-throughput deterministic lateral displacement device for rapid and sensitive field-diagnosis of sleeping sickness

We present a simple and rapid microfluidic device capable of extracting and concentrating the parasite causing the fatal disease sleeping sickness (SS) from blood. The device is based on deterministic lateral displacement (DLD) and constructed with a single inlet with flow induced by an ordinary syringe. The simplicity is crucial as the device is intended for use in the resource depraved areas whe

Meandering nanochannels for imaging of ultra-long DNA molecules

A new chip design for handling and studying chromosomal DNA is described. Folding the nanochannels enables us to image an entire yeast chromosome in a single field of view. Together with existing mapping techniques our new design opens up the possibility of directly analyzing entire chromosomes in a single field of view using fluorescence microscopy. This would enable, for example, identification

Multiple depths in a deterministic lateral displacement device for field-diagnosis of sleeping-sickness

We present a simple and inexpensive device capable of extracting and concentrating the parasite causing sleeping sickness from blood. The device is aimed at being used in rural resource depraved areas where the disease is endemic; therefore simplicity is of paramount importance. The device is based on deterministic lateral displacement with a single inlet and flow induced by a syringe. Through an

Re-industrialisation and low carbon economy – Can they go together? Results from transdisciplinary scenarios for energy intensive industries

This paper draws upon an extensive transdisciplinary scenario development in the context of the stakeholder oriented preparation of the climate protection plan of the German federal state North Rhine-Westphalia, which is home to the most important heavy industry cluster in Europe. In that context we developed differentiated bottom up climate change mitigation strategies and scenarios for the major

Interactive Balance and Walking Training for Stroke Survivors

In the ActivAbles and STARR projects we have developed interactive training tools for stroke survivors. A prototype system includes an interactive balance foam pad, feedback lamps and a step counting game app which all connect to a central server. The feedback is designed to be inclusive - designs are multimodal, and the setup is flexible and can easily be adapted. We describe the system and repor

Navigating Health Applications Realms : Consent Challenges and User Empowerment in European Law

This study delves into the landscape of health applications within online markets. These applications, offering health-related functionalities, have become integral to the lives of European citizens. The transformation of healthcare delivery, accelerated by the pace of modern life and accentuated by the COVID-19 pandemic, has elevated health applications from conveniences to essential tools capabl

Statistical Data Analysis of Inspection Outcomes of Post-Tensioned Concrete Bridges in Italy

Corrosion of cables can result in brittle and unexpected failures and represents a critical concern for prestressed concrete bridges with post-tensioned (PT) tendons. In these structures, corrosion is typically facilitated by inadequate grout injection and/or the use of poor-quality mortar during construction. Such deficiencies create favorable conditions for corrosion initiation and propagation.

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xpTVSM-4012 (2025-03) BACHELOR’S DISSERTATION AT STRUCTURAL MECHANICS EXAMENSARBETE I HÖGSKOLEINGENJÖRSUTBILDNINGEN VID LTH, CAMPUS HELSINGBORG DIVISION OF STRUCTURAL MECHANICS Faculty of Engineering LTH, Lund University, Box 118, SE-221 00 Lund, Sweden • Tel: + 46 (0)46-222 73 70 • Fax: + 46 (0)46-222 44 20 • www.byggmek.lth.se STORLEKSEFFEKT OCH BROTTMEKANISKA EGENSKAPER VID DRAGBELASTNING VINKE

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/education/bachelorprojects_THID/descriptions/xpTVSM4012.pdf - 2026-05-28

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Populärvetenskaplig sammanfattning till examensarbetet "Computational method for bulging in insulating glass units" Daniel Svensson Isolerglas består normalt av två eller tre separerade glasrutor. Mellan dessa skapas en kavitet som består av en fyllnadsgas för att öka den isolerande förmågan hos enheten. Kaviteten måste vara försluten för att gasen inte ska sippra ut och för att förhindra att fukt

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/education/masterprojects/popular_science/Popvet_5206.pdf - 2026-05-28