Filtyp
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the effects of caffeine compared to aminophylline or theophylline in preterm infants at risk of apnea, with apnea, or in the peri-extubation phase.
Treatment of chronic osteomyelitis by radical debridement and filling of the dead space with antibiotic containing calcium sulphate/hydroxyapatite (CaS/HA) bone substitute has shown excellent long-term outcomes. However, in extensive infections, sessile bacteria may remain in bone cells or soft tissues protected by biofilm leading to recurrences. The primary aim of this study was to evaluate if sy
Universities are increasingly being seen as a positive vehicle for territorial development and regional transformation, with an important role in enhancing Social, Economic and Sustainable Development of territories. The world’s sustainability challenges are listed in the United Nation’s Agenda 2030, that includes Higher Education Institutions (HEIs) as actors that can work in partnership with oth
Aims: The aim of this study was to investigate associations between having visited the theatre/cinema and an arts exhibition during the past year and all-cause, cardiovascular disease (CVD), cancer and other-cause mortality. Methods: The 2008 public health postal survey in Scania, Sweden, was distributed to a stratified random sample of the adult population (18–80 years old). The participation rat
The advent and popularity of shared electric scooters in many urban areas worldwide offer new opportunities and challenges to be addressed by the research community, especially as far as safety and accessibility issues are concerned. This paper proposes a methodology, based on geofencing technology (i.e., virtual geographic boundaries) to define in which urban areas the speed of shared electric sc
Background. We investigated how varying the treatment margin and applying hippocampal sparing and proton therapy impact the risk of neurocognitive impairment in pediatric medulloblastoma patients compared with current standard 3D conformal radiotherapy. Methods. We included 17 pediatric medulloblastoma patients to represent the variability in tumor location relative to the hippocampal region. Trea
This study investigated the dosimetric impact of uncompensated motion and motion compensation with dynamic multileaf collimator (DMLC) tracking for prostate intensity modulated arc therapy. Two treatment approaches were investigated; a conventional approach with a uniform radiation dose to the target volume and an intraprostatic lesion (IPL) boosted approach with an increased dose to a subvolume o
Responsible internationalization has become an increasingly used term to promote relationship building in a world which is increasingly shaped by the growing impact of global challenges and geopolitical competition. Amidst these changing global conditions researchers and universities have started to learn that they need to adhere to an expanded set of norms related to the research endeavor. Today
PurposeTo evaluate the long-term effect of laser trabeculoplasty (LTP) in patients randomized to multi-treatment in the Glaucoma Intensive Treatment Study (GITS).MethodsPatients with untreated newly diagnosed open-angle glaucoma were treated with three intraocular pressure (IOP)-lowering substances for 1 week and then 360° argon or selective LTP was performed. IOP was measured just before LTP and
Tumor antigens can emerge through multiple mechanisms, including translation of noncoding genomic regions. This noncanonical category of tumor antigens has recently gained attention; however, our understanding of how they recur within and between cancer types is still in its infancy. Therefore, we developed a proteogenomic pipeline based on deep learning de novo mass spectrometry (MS) to enable th
The sixth volume in the Interdisciplinary European Studies assesses the changes that are taking place in the EU’s policies, institutions, and political structures. On the eve of a new chapter of European integration in the dark shadow of the war in Ukraine, it is high time to assess the changes that have taken place in recent time and consider whether current developments are taking the EU on the
The majority of spatial data users are inexperienced in spatial information science. This group of users cannot analyze spatial data and produce the required information. Therefore, the availability of mechanisms and applications for automatic and interoperable spatial data processing and information extraction is necessary. Generalization is one of the main geoprocesses, which is widely used. The
Diffusion MRI is a non-invasive imaging technique used to study the microstructural properties of biological tissues by observing the self-diffusion of water molecules. Traditional diffusion MRI methods, based on the pulsed gradient spin-echo sequence, employ magnetic field gradients to encode information about translational motion. However, this approach combines various aspects of diffusion, suc
This study addresses the critical need to report original and current findings on the global food system's ability to meet the growing natural resource demands of an estimated 9?billion global population. The objective is to provide guidance for researchers in developing strategies to reduce climate change risks in the food and beverage supply. To achieve this, we propose integrating innovative in
BackgroundComplement activation in atypical hemolytic uremic syndrome (aHUS), C3 glomerulonephropathy (C3G) and immune complex-mediated membranoproliferative glomerulonephritis (IC-MPGN) may be associated with rare genetic variants. Here we describe gene variants in the Swedish and Norwegian populations.MethodsPatients with these diagnoses (N=141) were referred for genetic screening. Sanger or nex
In vivo magnetic resonance spectroscopy (MRS) is a powerful tool for biomedical research and clinical diagnostics, allowing for non-invasive measurement and analysis of small molecules from living tissues. However, currently available MRS processing and analytical software tools are limited in their potential for in-depth quality management, access to details of the processing stream, and user fri
Accurate density matrix simulation of nuclear spin systems is critical for quantifying magnetic resonance spectroscopy (MRS) data, as well as for simulation studies designed to optimize acquisition parameters. Although a variety of packages exist to achieve this result, no currently available software is capable of computing a large number of spatial points in a reasonable time frame. Here we pres
