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Book Review

The major inhibitor of the cysteine class of proteinases found in human body fluids, such as spinal fluid, milk, and seminal plasma, is cystatin C. In this study we show that human bronchoalveolar fluid also contains cystatin C and examine cystatin C expression by alveolar macrophages in vitro. Immunoprecipitation of extracts of metabolically labeled cells and immunoblotting of cellular extracts a

An integrated thermal biosensor array was designed and fabricated for the simultaneous determination of glucose, urea and penicillin. The sensor contains six thin-film thermistors which were fabricated on quartz chip by micromachining and semiconductor technology. This sensor allows the determination of three different analytes nearly simultaneously by serially partitioning a single microchan

An integrated thermal biosensor array was designed and fabricated for the simultaneous determination of glucose, urea and penicillin. The sensor contains ten thin-film thermistors which were fabricated on quartz chip by micromachining and semiconductor technologies. This sensor allows to determine maximum five different analytes nearly simultaneously by serially dividing the single microchannel in

Cystatin C, a 13 kDa-protein, is produced by most nucleated cells and is catabolized by the renal tubular cells after passing the glomerular filter. It belongs to the family 2 of the cystatin superfamily of proteins. The function of cystatin C is to regulate the activity of cysteine proteinases and cystatin C seems to be the main cysteine proteinase inhibitor of most investigated human biological

Lantbruket rankas konsekvent som en av de mest riskfyllda sektorerna i Sverige såväl som i många andra delar av världen. Förutom lidande för den enskilde beräknas dödliga och icke dödliga skador i svenskt lantbruk kosta samhället 2 – 3 miljarder kr per år. I Sverige inträffade det cirka 5 000 olyckor på jordbruksföretag 2004. Detta innebar att minst en olycka inträffade på 8% av svenska gårdar som

This paper describes the functional development of the ClimApp tool (available for free on iOS and Android devices), which combines current and 24 h weather forecasting with individual information to offer personalised guidance related to thermal exposure. Heat and cold stress assessments are based on ISO standards and thermal models where environmental settings and personal factors are integrated

Aim: Studies have suggested that there is a difference in risk of local recurrence(LR) with circumferential resection margins (CRM) less than 1.0 mm. We aimed toexamine how exact resection margins affect LR risk.Method: Data from the Swedish Colorectal Cancer Registry (SCRCR) were usedfor retrospective analysis of resected rectal cancers between 2005 and 2013. Primaryendpoint was LR.Results: 12146

This paper is focused on the analysis of two documents (the Council of Europe's Bioethics Convention and the Additional Cloning Protocol) inasmuch as they refer to the relationship between human dignity and human genetic engineering. After presenting the stipulations of the abovementioned documents, I will review various proposed meanings of human dignity and will try to identify which of these se

BACKGROUND: There is no consensus on best content, set-up, category of involved healthcare professionals or duration of rehabilitation-programs for patients with chronic musculoskeletal pain, and outcomes show varying results. Individual care regimes for sub-groups of patients have been proposed.AIM: To describe the type of interventions used in a physiotherapist-led, rehabilitation-program for pa

We propose a multivariate log-normal distribution to jointly model received power, mean delay, and root mean square (rms) delay spread of wideband radio channels, referred to as the standardized temporal moments. The model is validated using experimental data collected from five different measurement campaigns (four indoor scenarios and one outdoor scenario). We observe that the received power, th

Degrowth thought and strategies suffer from a tension between viewing the state as incapable of initiating transformational change and making a political appeal to it to do precisely this via targeted eco-social policies. While a small number of academic papers has theoretically addressed this tension, there is a lack in research on the strategic implications arising from conceptualizations of the

Purpose: Hypoxia (low oxygen) is a common feature of solid tumors that has been intensely studied for more than six decades. Here we review the importance of hypoxia to radiotherapy with a particular focus on the contribution of hypoxia to immune responses, metastatic potential and FLASH radiotherapy, active areas of research by leading women in the field. Conclusion: Although hypoxia-driven metas

Study region: The Kaidu River Basin (KRB) is located on the central southern slope of the Tianshan Mountain in Northwest China. Study focus: This work aimed to assess changes and main drivers of snowmelt-driven runoff in KRB associated with three future climate scenarios. Six versions of the “Cemaneige” snowmelt module embedded in the hydrological model “GR4J” were calibrated and evaluated. The bi

Implementing energy efficiency measures in historic buildings is a challenging task and require knowledge in a number of different disciplines. The measures to reduce energy use must create a good indoor environment without jeopardizing the loss of important cultural historical values or entailing damages to building materials or load-bearing structures. Building antiquarian-, building biological-

AimsPatients with advanced heart failure (AdHF) who are ineligible for heart transplantation (HTx) can become candidates for treatment with a left ventricular assist device (LVAD) in some countries, but not others. This reflects the lack of a systematic analysis of the usefulness of LVAD systems in this context, and of their benefits, limitations and cost-effectiveness. The SWEdish evaluation of l

Anthropomorphic phantoms are models of real or virtual parts of the body, organ or tissue, represented by tissue-equivalent materials that aim to provide a realistic and accurate representation of their anatomy and properties. The aim of this study is to evaluate experimentally the suitability of 3D printed materials in the production of both, physical breast phantoms and abnormalities, to be used