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Vanuatu is one of the most hazard prone nations in the world and frequently tops the World Risk Report as the nation with the highest overall disaster risk. The devastation wrought by category 5 cyclone Pam (2015), the El Niño drought (2015/16), and volcanic eruptions in Ambae (2018), are but a few recent examples of disasters which have disrupted livelihoods and curtailed development. The Vanuatu
A recent genome-wide association study reported five loci for which there was strong, but sub-genome-wide significant evidence for association with multiple sclerosis risk. The aim of this study was to evaluate the role of these potential risk loci in a large and independent data set of ≈ 20,000 subjects. We tested five single nucleotide polymorphisms rs228614 (MANBA), rs630923 (CXCR5), rs2744148
BACKGROUND: Preterm infants are susceptible to hyperglycemia and hypoglycemia, conditions which may lead to adverse neurodevelopment. The use of continuous glucose monitoring devices (CGM) might help keeping glucose levels in the normal range, and reduce the need for blood sampling. However, the use of CGM might be associated with harms in the preterm infant. OBJECTIVES: Objective one: to assess t
The simulation model which examines the dynamic behavior of real structures needs to address the impact of uncertainty in both geometry and material parameters. This article investigates three-dimensional finite element models for structural dynamics problems with respect to both model and parameter uncertainties. The parameter uncertainties are determined via laboratory measurements on several be
Background: Dizziness is common among patients with first time stroke. It affects self-perceived health and is a risk factor for falls. Vestibular rehabilitation (VR) is effective for treating dizziness among various conditions, but the effect of dizziness with origin in the central nervous system is poorly studied. This pilot study of a randomized controlled trial aimed at investigating a vestibu
Lunds universitet fick i uppdrag av Kemikalieinspektionen att kartlägga och beskriva ansatser till metoder som bedömer indirekta effekter av växtskyddsmedel på individer och populationer och studier som utvärderar om nuvarande riskbedömningsmetoder är tillräckliga för att bedöma direkta effekter av växtskyddsmedel på biologisk mångfald. Uppdraget utfördes i två delar. För det första inventerade viLund University was commissioned by the Swedish Chemicals Agency to map and describe emerging methodologies that assess the indirect impact of plant protection products on nontarget organism individuals and populations, and studies that evaluates if current risk assessment methodologies are sufficient to assess direct effects of plant protection products on biodiversity. The commission was perform
Effective and efficient governance is driven by policies that prevail in urban contexts. Policies are usually the result of knowledge co-production, but the efficacy of the process of translating knowledge into policy is still not well defined in the Kenyan context. One example of this is the city of Kisumu, which has been the focus of knowledge co-production by researchers from Kisumu and Gothenb
We present a range of numerical tests comparing the dynamical cores of the operationally used numerical weather prediction (NWP) model COSMO and the university code Dune, focusing on their efficiency and accuracy for solving benchmark test cases for NWP. The dynamical core of COSMO is based on a finite difference method whereas the Dune core is based on a Discontinuous Galerkin method. Both dynami
Synaptic pathology is a central event in Alzheimer’s disease (AD) and other neurodegenerative conditions, and investigation of synaptic proteins can provide valuable tools to follow synaptic dysfunction and loss in these diseases. Neuroligin-1 (Nlgn1) is a postsynaptic cell adhesion protein, important for synapse stabilization and formation. Nlgn1 has been connected to cognitive disorders, and spe
Background: Commercially available software for cardiovascular image analysis often has limited functionality and frequently lacks the careful validation that is required for clinical studies. We have already implemented a cardiovascular image analysis software package and released it as freeware for the research community. However, it was distributed as a stand-alone application and other researc
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess and compare the effects and complication rates of licensed bioengineered nerve conduits or wraps for surgical repair of traumatic peripheral nerve injuries of the upper limb. To compare effects and complications against the current gold surgical standard (nerve autograft).
Two patients with idiopathic Parkinson's disease (Patients 3 and 4 in our series) were followed up to 3 years after grafting of human embryonic dopamine-rich mesencephalic tissue unilaterally into the putamen. During the first postoperative year both patients showed significant amelioration of parkinsonian symptoms and increased 6-L-[18F]-fluorodopa uptake in the grafted putamen, as assessed with
Oxygenic photoautotrophs require mechanisms for rapidly matching the level of chlorophyll excited states from light harvesting with the rate of electron transport from water to carbon dioxide. These photoprotective reactions prevent formation of reactive excited states and photoinhibition. The fastest response to excess illumination is the so-called non-photochemical quenching which, in higher pla
Visual abilities of the honey bee have been studied for more than 100 years, recently revealing unexpectedly sophisticated cognitive skills rivalling those of vertebrates. However, the physiological limits of the honey bee eye have been largely unaddressed and only studied in an unnatural, dark state. Using a bright display and intracellular recordings, we here systematically investigated the angu
